Link to Topical Finasteride

[DepressedByHairLoss]

Not sure how legit this is, but I found this: http://innovativemen.com/topical-fin...tment-seattle/

[rdawg]

a few questions:

1. How easy is this to make/get my hands on?

2. Would the benefits in theory at least be greater than regular oral fin due to it being more direct/localised?

[PatientlyWaiting]

The website looks well-made, unlike some hair loss products websites I have seen that look like they were made by a 6 year old with Microsoft Paint. But I rather wait a little while to see if a reputable company comes out with topical fin.

[TO YOUNG TO RETIRE]

why dont we contact them to buy some?maybe a group buy too?

[santos]

Ohh wow. This is right in my neighborhood. Thanks for the link. I may pay them a visit.

[TO YOUNG TO RETIRE]

santos can you ask if they can ship to europe and if its absorded systemycaly

[santos]

TO YOUNG TO RETIRE: Sure. Im just recently started to worry about hair loss and found this forum. So the reason I want to go in is to find out where im at.. get some info. I think im a NW3, not sure.

[TO YOUNG TO RETIRE]

i think we have the same nw santos

[santos]

Im kind of overwhelmed with all the info on this forum.. people trying one thing others trying something else.. its all good info. but I don't know which way to go with it.

[Cob984]

Im kind of overwhelmed with all the info on this forum.. people trying one thing others trying something else.. its all good info. but I don't know which way to go with it.

This, One day im like lets just continue with Kar, the 2nd day RU, the third topical Fin, the 4th some Spectral product. FML,
the worst part is inspite of all the combinations there is nothing that really helps my hair w/o sides, feel like im cursed

[clandestine]

Better than a lack of options..

[zephyrprime]

I made my own topical dutasteride solution by crushing some pills into a premade rogaine solution. It had no effect. However, finasteride has a lower molecular weight than dutasteride (372.55 vs 528.53 g/mol) so maybe it would work better .

[HARIRI]

Topical Finasteride is very interesting indeed, however I still need to see it to be sold officially in pharmacies and drugstores. By then I will give it a try as oral Finasteride gave me great results but a lot of sexual sides. I hope the topical formula will solve the libidio issue somehow.

[Arashi]

This was presented at the 7th world congress of hair research:


P040
Pharmacodynamic of P-3074 (finasteride 0.25% topical solution) in subjects with
androgenetic alopecia

M Caserini1, R Palmieri1, M Radicioni2 and E Terragni2 1Polichem S.A., Lugano, Switzerland and
2Cross Research S.A., Arzo, Switzerland

A new proprietary topical formulation, P-3074, containing finasteride 0.25% as active ingredient
and hydroxypropyl-chitosan (HPCH) as film-forming agent, was developed for androgenetic
alopecia. The present study was aimed at investigating the pharmacodynamic profile of
finasteride in terms of dihydrotestosterone (DHT) concentrations in the scalp and in serum after
multiple topical application of P-3074 or oral finasteride intake in subjects with androgenetic
alopecia. Eighteen healthy men were randomly allocated to P-3074 or oral treatment after
providing written informed consent. Twelve volunteers applied P-3074 topical solution for 7
days: six subjects once daily (o.d.) in the morning and the others twice daily (b.i.d.) in the morning
and in the evening. The third group of six volunteers was administered 1mg oral finasteride once
daily in the morning for 1 week. Scalp (vertex) biopsies were collected at baseline and 6 hours
after last dose administration, while serum samples were collected at baseline, before last
administration, and 6 and 12 hours after the last multiple dose.

A marked decrease in scalp DHT levels was observed:

by 47.22% with P-3074 b.i.d., from 1.91 (±0.54) to 1.01 ng ml1 (±0.39),
by 71.20% with P-3074 o.d., from 1.52 (±0.41) to 0.44 ng ml1 (±0.0, and
by 51.11% with the oral formulation, from 1.39 (±0.25) to 0.68 ng ml1 (±0.34).

Serum DHT was reduced by
69.3–74.0% with P-3074 b.i.d., 67.6–80.4% with P-3074 o.d., and
69.7–76.1% with the oral formulation.

These results showed a similar inhibition of serum DHT after 1 week of finasteride
administration with the three dose regimens and were consistent with the results obtained in a
previous P-3074 PK study. These findings show that DHT concentration in the scalp, after 7-day
treatment course of P-3074 o.d., was more reduced (about 40%) than after 1mg oral finasteride
administration for the same treatment period

[Pentarou]

Topical Finasteride is very interesting indeed, however I still need to see it to be sold officially in pharmacies and drugstores.

Same. I'd jump at the chance to switch to topical fin, for the additional effect on scalp DHT, but I'm not willing to try the DIY approach.