Hellouser's RU Log (with Minox, CB Nizoral and Saw Palmetto)

[inbrugge]

This is out of the blue, but are there any studies on RU? Was it discovered accidentally or what?

I know the story about CB a bit, and I'm aware there has been research and trials going on. But nothing about RU?

I'm against most antiandrogens, especially oral ones. I'm more inclined towards RU because it's topical. But I'm still skeptical about side effects (and pricing).

Really, can anyone tell me why RU is safer than Fin/Dut apart from it being topical?

[lilpauly]

Simba, I'm using about .9 grams a day. I might start using .75 a day. I used rogaine 5% for a year, and I lost easily at LEAST 100 strands whenever I would apply it and I would apply it twice a day. I never thickened any existing hair or grew back any lost hair outside of some long and super-thin strands (very, very few). RU58841 really does seem to be working, at least based on the first hair cut I had. Hopefully, when I cut my hair this time, I'll notice a bigger difference.

I am also curious as to the proof that shedding is good.

This is out of the blue, but are there any studies on RU? Was it discovered accidentally or what?

I know the story about CB a bit, and I'm aware there has been research and trials going on. But nothing about RU?

I'm against most antiandrogens, especially oral ones. I'm more inclined towards RU because it's topical. But I'm still skeptical about side effects (and pricing).

Really, can anyone tell me why RU is safer than Fin/Dut apart from it being topical?

Bro it's a experimental drug . Elder posted studied on hlh I will find them about ru . Cb is safter but we don't have a vehicle . Asc j9 is another anti androgen without a vehicle . Both are in trials now

[doke]

This is out of the blue, but are there any studies on RU? Was it discovered accidentally or what?

I know the story about CB a bit, and I'm aware there has been research and trials going on. But nothing about RU?

I'm against most antiandrogens, especially oral ones. I'm more inclined towards RU because it's topical. But I'm still skeptical about side effects (and pricing).

Really, can anyone tell me why RU is safer than Fin/Dut apart from it being topical?

RU58841 was discovered by french rousell drug company and although it had trials for alopecia and was said to be none systemic and safe did not come to anything i think it was also said it was 100% dht blocker like topical flutamide but without the systemic side effects.
I remember on one forum it was called the mother of all antiandrogens but i think that the mix and the half life of ru is the problem some batches worked and some did not and due to that and of course another company postraken took over ru which i think is based in scotland they dropped the trials and no one knows why was it money or there just not interested in alopecia.

[Atum]

So is it safe to say that Rogaine doesn't work, but that it actually makes your hair worse?
I've read multiple bad posts regarding Rogaine and i am using it on and off, cause i'm not sure about it.

[win200]

So is it safe to say that Rogaine doesn't work, but that it actually makes your hair worse?
I've read multiple bad posts regarding Rogaine and i am using it on and off, cause i'm not sure about it.

Not safe to say that. Rogaine works for a majority of users. Some people get only marginal benefits from it, but most people see SOME positive results. It's very unusual for Rogaine to make you worse off than you were before you started using it.

Also, DON'T use it off and on. It only works if you use it on a consistent, steady basis. Off-and-on use could exacerbate your problem; Rogaine usually causes a shed when you first start using it, as the weaker hairs fall out and grow back stronger. If you're going back and forth, you could be causing the weak hairs to fall out without providing them the nourishment needed to grow back stronger. Use it or don't use it, but make a firm decision.

[Imalmostbald]

RU works great for me and at 200mg it really thicked up my hair to where aga all started. It is really a beast of a treatment.

[nliyan25]

200 mg?

RU works great for me and at 200mg it really thicked up my hair to where aga all started. It is really a beast of a treatment.

Imalmostbald, is it safe to go above 100 mg? In Hellouser's guide, he suggests never to go above 100 mg, I thought.

[Imalmostbald]

Imalmostbald, is it safe to go above 100 mg? In Hellouser's guide, he suggests never to go above 100 mg, I thought.

Evaluate such things for yourself. I myself did up to 250-300 mg. I think hellouser mentioned not going above 100mg because it is not probably more favourable than doing 200mg. You surely do increase anti androgenic side effects with a bigger dosage your going. Another guy from a forum did upwards 400mg if im not mistaken, but said it did not differ that much from 100mg.

I got long hair so thats why i also use more to ensure a minimum of 100mg gets in contact with my scalp.

[Atum]

Not safe to say that. Rogaine works for a majority of users. Some people get only marginal benefits from it, but most people see SOME positive results. It's very unusual for Rogaine to make you worse off than you were before you started using it.

Also, DON'T use it off and on. It only works if you use it on a consistent, steady basis. Off-and-on use could exacerbate your problem; Rogaine usually causes a shed when you first start using it, as the weaker hairs fall out and grow back stronger. If you're going back and forth, you could be causing the weak hairs to fall out without providing them the nourishment needed to grow back stronger. Use it or don't use it, but make a firm decision.

I only used it on the spot where some vellus hair is popping out, in the hope it starts growing again. Never used it on my 'normal' hair before, for the reason that i don't want a shed on the front.

[nliyan25]

Increased shedding

Evaluate such things for yourself. I myself did up to 250-300 mg. I think hellouser mentioned not going above 100mg because it is not probably more favourable than doing 200mg. You surely do increase anti androgenic side effects with a bigger dosage your going. Another guy from a forum did upwards 400mg if im not mistaken, but said it did not differ that much from 100mg.

I got long hair so thats why i also use more to ensure a minimum of 100mg gets in contact with my scalp.

Imalmostbald, is it normal to have an increase in shedding if you increase the mg of RU used? I moved up from 80 mg to 150 mg and I think I noticed an increase in shedding.

[doke]

Many of you have seen me post and boast about RU and many of you have also inquired about my progress... well, here is my log.

I noticed my hair going bad.. I mean really bad back in around March of 2011. I didn't notice it thin out or anything, but rather my hair line go waaaay back than what it used to be. I noticed this after I was at a club with friends and had some pictures of myself taken. The lighting on my face was rather harsh and it exposed a lot of scalp behind the hairline which made the hairline look higher than it actually is. This is where my life started going downhill..... its when I realized I looked ****ing weird and it was my hair. By this time I was already an NW2-3, but I never really took much notice into my hairline.. I didn't care about it before, I thought I looked normal (I mean I still do, but society is full of shithead assholes so no, by their standards I dont look normal).

February, 2011 - Before Regimen
So I started reading about things that can be done. I learned about Saw Palmetto, Nizoral, Finasteride, hair transplants and Replicel. I read about Finasteride castrating men and giving many side effects and it was a complete write off. It still is and its a dangerous drug which no man should take. I'm not saying I'd take it away from those who are already on it with results, but Finasteride is pure bullshit. My first line of defense? Saw Palmetto, and even with that I was hesitant as I ready about mild effects. But the bad breathe issue was the worst problem. It subsided eventually though.

Here's what my hair looked like then (these are from a club, so apologies for the crappy quality). Mind you, I used to use a good but 'wet' product called Bedhead by Tigi. This makes hair look quite thin as it climps hair real close together, hence it looking thin below.







So here's where I start fighting this disease that nobody cares about;

April, 2011
I start taking saw palmetto. Did my research, relatively small sides if any, much safer than finasteride, 1 pill a day (eventually moved up to 2 pills a day, 160mg each). Also started using Nizoral.

June, 2011
I start taking Kirkland's Minoxidil 2%, twice a day. I suppose in the pics below I shed a bit however I don't remember freaking out about hairs in the tub or on my pillow.





October, 2011
Ordered 5grams of RU from Ontario Chemicals and start using in 1ml application of 0.7ml isopropyl (wrong vehicle) and 0.3ml of PG. Concentration of RU was probably about 10mg. USELESS. At this dosage, almost impossible to get side effects more so since I was using isopropyl.
RU is now applied once daily, Minoxidil once daily as well.

March, 2012
In the picture below I am 5 months into using 1ml of RU with about 1-2% concentration (10-20mg) with about 1ml of Minoxidil at 2%. I should mention that while I'm on this regimen, I often used only 0.5ml total per day which all went into my hairline. The rest of my pathetic head I battled with Minox.



September, 2012
Ran out of 5g of RU (yeah, after 11 months). Order 10g of RU from Ontario Chemicals again, still using Isopropyl but upped the dosage of RU to 5% concentration per 1ml (so 50mg per 1ml) and used once daily. Still on Minoxidil 2% once daily, still on Saw Palmetto and Nizoral.

No further loss, no shedding still but no regrowth either.

October, 2012
Below we can see I've had regrowth!





December, 2012
Ran out of 2% Minoxidil from Kirklands, changed it to Kirklands 5%.

MASSIVE SHEDDING (therefor, major loss in density).

Hair got thinner immediately in the following weeks.
Still on RU at 5% in 1ml, Saw Palmetto and Nizoral.

January, 2013
Below is a photo of my hair RIGHT after a lot of Minox was applied all over and we see a drastic change for the worse. The shedding from the switch to Minoxidil at 5% is evident and things look terrible. Mind you in the photos below I am using between 1.5-2ml of Minoxidil and these pictures are IMMEDIATELY after application hence my hair looks wet and thin.





February 6th, 2013
Photos below show whats going on:



February 15th, 2013
STILL SHEDDING and most likely due to going from 2% to 5% minoxidil. Shedding is common and usually a sign of efficacy. Ran out of RU, got 10g again of RU, but also purchased Everclear to fix the vehicle. Upped the dosage of RU to about 100mg per 1ml (thus 10% solution) once daily.



Below it is very VERY clear I've lost a lot of density.




March, 2013
Shedding slowing down significantly. No regrowth yet however small hairs have shown up around the hairline.

April 19th, 2013
Havent had a haircut since January/February so hair is quite long. Still shedding. But: LOTS of new hairs have sprouted around the hairline and the small hairs at hairline visible 1 month prior are now longer, but only visible when seen up close. I hope the same holds true for the vertex and crown to hold onto my hair until Aderans/Histogen is out.





April 20th, 2013
Day of haircut! Behold! Density is back!





Currently:
Today is May 1st, and I recently added CB once daily at 1% (1-1.5ml) thus the new regimen is now:

100mg RU in 1ml, once daily
10-15mg CB in 1ml or 1.5ml, once daily
Minoxidil 5% at about 1.5ml, once daily
Saw Palmetto (320mg - 550mg daily, depending on available pills)
Nizoral 2%

I'm also using some shampoos with Saw Palmetto and am planning on acquiring MiN New York hair products (a clay which contains saw palmetto and azelaic acid, probably useless but better than nothing).

I've also noticed THICK and DARK terminal hairs show up at the hairline! These are hairs I dont remember seeing from a while back and potentially havent been around in years! There aren't many, maybe about 20, but its a clear sign things are working.

Future treatment:

I recently acquired Lubrajel, the same vehicle used in the study for BNP-32 as a topical treatment for hair loss. You can read about this peptide here or my general summary here

I have quite a bit of cash saved up for a surgical treatment for Dr. Gho, but if the guys from other forums already experimenting with BNP-32 get results, I will be buying some BNP-32 myself and using my lubrajel to regrow the temples and entire scalp. If that fails, its Gho time (or someone else that can offer regeneration).

- - - - - - - - - - - - - - - - - - - - - - - - - - - -

I do want to say though that the last two years of my life have EASILY been the most depressing, most angry, most lacking. I'm trying to wait very patiently for a treatment from Histogen and Aderans.

If anyone is curious about how effective is CB? I don't know yet, its too soon to tell.

As for side effects? None from RU as far as I can tell. No brain fog, no limp-finasteride-dick however I have experienced many drops in Libido from Saw Palmetto. Whats weird is that sometimes my libido is RAGING high and I'll be getting random stiffies at work too. Though I suppose the reduced libido could also be due to physical inactivity and general depression.

I hope this helps. I'll post more in the future.

Also, if anyone wants to know how to acquire, mix, apply, etc RU, I've made a complete guide here; http://www.baldtruthtalk.com/showthread.php?p=120497

Hi hell i am guessing you are in your 30s and my hair loss was like yours and minoxidil+progestorone 4% seemed to help and after six months my hair was quite thick but not as much as i would like so i wonder if combining cb or ru with minox and progestorone would be a good thing to try.
I must say we must thankyou for your pics and info thats a great help to what may and maynot work the shedding at times seems the same as irish pride on the other forums he had on and off great results with minox ans ru but at times massive sheds and then totall regrowth its terrible this affliction and even though many know im in my 50s now im still seeking something to regrow my hair im lucky i still have some left but for me since my late 20s its been devistating.
Have you tried topical spironolactone with minox or tretinoin.

[Amercancer]

Ru mixed with rogaine

Is it ok to mix RU and rogaine all over top of scalp?

[Amercancer]

I just received my RU, and a bottle of ethanol 98%. I also ordered a bottle that's H20, Ethanol, Cremophor RH410, Luviquay FC 550. What should I go whith his and which and tell me if I need anything else. Please help me put this together in the best way. Thanx will appreciate it.

[doke]

by the way has anyone got an email from mpb treatments they are saying they are soon restarting there products again.

[strife91]

Is it ok to mix RU and rogaine all over top of scalp?

Yeah mixing ur ru with rogaine should be fine