RU is working wonders on Hairloss Help

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  • Troy
    Member
    • Aug 2012
    • 73

    I answered this a few days ago in this thread...

    Not an anti androgen and much more than a growth stimulant.

    It works on bone morphogenic protein (BMP). As stated, not only does it increase BMP2 (hair growth) and decrease BMP4 (hair loss) but it also inhibits the way the immune system attacks the hair follicle during MPB (anti-inflammatory properties) and inhibits cell apotosis (cell death) in the follicle. Aside from inhibiting proteasomal activity it also decreases the activity of the transcription factor NF-.kappa.B.
    The most exciting part about this treatment is that it works in a totally unique fashion. “Topical administration of OSH101 strongly stimulates dormant hair follicles, increases hair follicle thickness, and overall hair growth” So it’s not going to just affect existing hair like Minox does, it affects DORMANT follicles as well. In the trials, there was a 5% increase in total hair count in JUST 28 days of treatment

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    • Jazz1
      Inactive
      • Aug 2012
      • 1598

      How much is PSI and how is it mixed or used etc?

      Comment

      • clandestine
        Senior Member
        • Aug 2011
        • 2002

        Originally posted by lilpauly
        PSI IS NOW available!
        For 400$/g

        Comment

        • Jairus
          Senior Member
          • Feb 2012
          • 191

          I see on mpbtreatments that they have RU in a cream. Is this just applied normally out of the tin? Any dissolving needed? Seems to be easier to apply topically.

          Can anyone comment on this?

          Comment

          • Troy
            Member
            • Aug 2012
            • 73

            Originally posted by Jairus
            I see on mpbtreatments that they have RU in a cream. Is this just applied normally out of the tin? Any dissolving needed? Seems to be easier to apply topically.

            Can anyone comment on this?
            You apply the cream directly to the scalp...No need to dissolve it in anything!

            If you have shaved/buzzed hair it's good to apply...I have a bit long hair, so it's a nightmare, unless you only apply to the hairline.

            Comment

            • Troy
              Member
              • Aug 2012
              • 73

              Originally posted by Jazz1
              How much is PSI and how is it mixed or used etc?
              The concentrations used in the trials were 0.5%, 1%, 2% and i think they even used 5%!

              The vehicle is very simple: ethanol, PG, distilled water

              Comment

              • Jairus
                Senior Member
                • Feb 2012
                • 191

                Originally posted by Troy
                You apply the cream directly to the scalp...No need to dissolve it in anything!

                If you have shaved/buzzed hair it's good to apply...I have a bit long hair, so it's a nightmare, unless you only apply to the hairline.
                Cheers Troy

                Do u use it yourself? In terms of applications would it be once a day?

                Is the cream stronger than the liquid RU?

                I know its a topical anti androgen, but since it seems to penetrate the scalp more, could there be sides?

                Comment

                • Troy
                  Member
                  • Aug 2012
                  • 73

                  Originally posted by Amino
                  Hi Gents,

                  I'm finding the 5% solution from MPB too strong for me (i was also very sensitive to Dut).

                  Rather than waste it, anyone have any thoughts on dilluting it to the equivilent of 1% solution? Can I just mix it with something? Any thoughts?

                  Thanks.
                  This question got me thinking...

                  So in the patents of K&B solution, the solutions of 5% and 2% are:

                  Kraemer & Bohn’s 5% RU58841 solution (KB5)
                  - 27% Demineralized water
                  - 63% Ethanol (96%)
                  - 2.5% BASF Cremophor RH 410
                  - 2.5% BASF Luviquat FC 550
                  - 5% RU58841
                  Kraemer & Bohn’s 2% RU58841 solution (KB2)
                  - 54% Demineralized water
                  - 40% Ethanol (96%)
                  - 2% BASF Cremophor RH 410
                  - 2% BASF Luviquat FC 550
                  - 2% RU58841
                  So let's say we want to transform your 5% into 2%, and what you can easily get is distilled water and ethanol.

                  The ratios change mainly in these two.

                  60ml 5% solution contain 27% water (something like 16.20 ml) and 63% ethanol (something like 37.80 ml)

                  You have to start with yours 60ml, let's assume you'll make the double of this - 120 ml - wich will get you a little more than 2% of RU concentration, and we can try to base our math in the Kraemer & Bohn’s 2% RU58841 solution.

                  120ml 2% solution contain 54% water (something like 64.80 ml) and 40% ethanol (something like 48.00 ml)

                  Based on the diferential of water between 5% (60ml) and 2% (120ml) (16.20ml / 64.80ml) I guess you can try to add something like 48ml of distilled water.

                  Based on the diferential of ethanol between 5% (60ml) and 2% (120ml) (37.80ml / 48.00ml) I guess you can try to add something like 12ml of ethanol (96%).


                  I don't know if this will work...I would appreciate also someone's thoughts on this...


                  Resuming: Add 48ml of distilled water and 12ml ethanol (96%), you will get 120ml with a much more diluted solution.

                  Comment

                  • Troy
                    Member
                    • Aug 2012
                    • 73

                    Originally posted by Jairus
                    Cheers Troy

                    Do u use it yourself? In terms of applications would it be once a day?

                    Is the cream stronger than the liquid RU?

                    I know its a topical anti androgen, but since it seems to penetrate the scalp more, could there be sides?
                    I'm expecting to use PSI very soon...Never tried it before.

                    In trials PSI was used in cycles like 14 days or 21 days. I'm thinking about using it for 21 days cycle then stop for like a month maybe...I'm not sure right now...

                    The cream is for RU58841-Myristate and the difference between this and regular RU58841 is that it has a myristate lipid tale attached. In trials it was shown to be more safe and more effective then the regular RU, having better targeting of the dermal papilla cells.

                    I think that people that tried this with the old cream formula didn't had results because the cream recipe was wrong...I also think that this cream is the new/correct formula...

                    I tried RUM before in a emu oil / PG vehicle but it was too much of a greasy mess for me...I wasn't consistent with it and dropped it...

                    Comment

                    • Jairus
                      Senior Member
                      • Feb 2012
                      • 191

                      Originally posted by Troy
                      I'm expecting to use PSI very soon...Never tried it before.

                      In trials PSI was used in cycles like 14 days or 21 days. I'm thinking about using it for 21 days cycle then stop for like a month maybe...I'm not sure right now...

                      The cream is for RU58841-Myristate and the difference between this and regular RU58841 is that it has a myristate lipid tale attached. In trials it was shown to be more safe and more effective then the regular RU, having better targeting of the dermal papilla cells.

                      I think that people that tried this with the old cream formula didn't had results because the cream recipe was wrong...I also think that this cream is the new/correct formula...

                      I tried RUM before in a emu oil / PG vehicle but it was too much of a greasy mess for me...I wasn't consistent with it and dropped it...
                      Sound thanks

                      Was RUM doing anything for you when u tried it? Does it work in the same way propecia does? Or a diff mechanism?

                      Comment

                      • Jazz1
                        Inactive
                        • Aug 2012
                        • 1598

                        Ok guys just had an email from MPBtreatments iv cancelled my dispute and accepted them to refund me when ever they can, as I don't want them spending more on delivery as it was an error and I guess I over reacted with anger, these guys are genuine after all and yes their products do work so hopefully I can carry on ordering from them. Email they sent,

                        "Hello, I would like to apologize for the delay in our response to your
                        question, we recently had some technical difficulties with our webmail
                        service. To answer your question- There must have been an error with our
                        shipping department if you only received one bottle, we will take care
                        of this at our expense, we apologize for our human error. Regarding your
                        concern over the amount of liquid in the bottle, as indicated on our
                        webshop each one of our RU solutions is sold in the amount of 2oz or 60
                        ml, I would like to implore you to measure the amount of liquid in your
                        bottle, you will see upon inspection that hte bottle contains 60mls as
                        indicated on the website; however, the bottles that we ship in are 80ml
                        bottles, this is why the bottle is not filled to the brim because the
                        bottle has an 80ml capacity not 60ml, however you are still receiving a
                        60ml solution which will last from one to two months depending on
                        whether you use one or two mls per day. please let me know what address
                        you would prefer us to send your extra bottle to."

                        Comment

                        • JJacobs152
                          Senior Member
                          • May 2011
                          • 293

                          I think it's hilarious, that not a single person has asked for purity papers. Don't you guys want to know what you ordered is 99.9% pure product, and doesn't have any impurities.

                          Why haven't those papers been posted?

                          Comment

                          • lilpauly
                            Senior Member
                            • Feb 2012
                            • 1084

                            People who are ordering from the group buy will have the Ru tested by a third party

                            Comment

                            • lilpauly
                              Senior Member
                              • Feb 2012
                              • 1084

                              group buy extended!
                              OFFICIAL GROUP BUYS:

                              Minoxidil Sulphate $27/100g
                              Adenosine $17/100g
                              Actual Valproic Acid (VPA) $17/100ml
                              GHK-Cu (Copper Peptide) $80/5g
                              AHK-Cu (Copper Peptide) $90/5g
                              Thymosin Beta 4 (TB-500) $285/80mg
                              RU-58841 $180/10g
                              K&B 5% Solution $46/250ml

                              we are currently testing the ru and tb

                              Comment

                              • dex89
                                Senior Member
                                • Jul 2012
                                • 808

                                GOOD, can't wait to buy RU and KB.

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