Dr Klein promox patients! Read if you need help.

[Jazz1]

Thanks for the response Jazz.....

Currently I am on:

dut 0.5 twice a week and propecia 1mg all other days
I also alternate between rogaine foam 5% and minoxidil 5% liquid once daily.
Shampoo: Niz 2%/ T-sal each once a week

I am Ok with my anti DHT regimen.

What I am struggling with is possible inflammation and itching with the rogaine/minoxidil. I have tried different combos (I have been on them for over a year), different timing (twice daily vs once daily), different shampoos...but I think they are just too harsh for me and I don't think skin irritation is helpful. Having said that, while I didn't regrow with minoxidil/rogaine, but it may have helped thicken the exisiting hair I had.

So basically I am looking for a different preparation and hoping its not as rough on me.


Maybe I am allergic to PG, that's my guess. Maybe I should go with the glycerin base.

Then again, what do you think of the importance of DMI? I guess the question is are a PG/DMI base much more effective at delivering the ingredients than just the glycerin base? Anyone have any thoughts on this? Seems like the website now does not allow for a glycerin/DMI base anymore.



And yeah.... I am wondering if I should go with a separate cream like u for hydrocortisone (and apply it 1% once weekly)..... my worry is the hydrocort might make Susans mixture too thick like some people may have reported? What do you think? If I go with a separate hydrocort only once weekly, do I still add tretinoin to susans mixture?





Keep up the good work, you are a great resource for this community.

That is a good regime you have going on, are you looking to regrow some hair? How are your temples?

Hey as mentioned by Plan C I would drop the liquid minoxidol and carry on with the foam, as the liquid version also gave me itchy annoying scalp. When did you add the liquid and foam? Were they added the same time? Also have you considered Regenpeure Dr and Nt, great shampoo to add with great ingredients to help keep your scalp environment clean and healthy.

DMI (Dimethyl Isosorbide) is a very good compound, if your looking to gain some regrowth than I would also add tretinoin. The only downside with tretinoin is it may cause minor irritation at the start, this normally subsides after 1/2 months. The more ingredients you add it will be more beneficial as they are all proven to work synergistically than alone. I personally would add hydorcortisone to the mixture as its all included in the one price, so no extra charge to add all the ingredients

Again I never had any irritation on Susan's mixture apart from the tretinoin at the start and slight head rush due to 15% minoxidol. All the side effects I experienced have now disappeared and I seem to have gained more positive results when I switched over to her lotion, temple vellus hairs are growing longer.

Yes you are correct from my understanding people who added hydorcortisone to the mixture have had a slightly thicker lotion/cream. But saying that it is still very effective as the liquid lotion, as a guy has been updating me on his hairloss via watts app and is very happy he uses the Hydocortisone mixture. I'm sure Susan could try her best in making it more liquid like mine, best to phone her before your lotion/cream mixture is made. If your worried about irritation I would best give Susan a call, she is very helpfull and more knowledgable than me regarding vehicle irritation .

Thank you for the kind words, I'm only trying to keep up with my promise I made to GOD, I was helped 5 years back by the hairloss forum community so I'm just repaying my promise to help others , no need to thank me thank the forum members.

[Plan C]

Thanks Plan C!

I definitely appreciate your input. And will look into trying that approach. I have Cerave cream here in the US, which is pretty darn good. We don't have E45 unfortunately.

Do you feel like there was any drop off in results when you switched entirely to foam? I need to convince myself that there isn't. lol.


How are things going with susans lotion?

Do you think its less irritating? Do you think it goes on better than liquid minox (esp in terms of drying/grease factor)? Did you ask for the lotion or the cream?


And finally what made you switch away from regular minox?

If liquid minox is better than the foam, it's barely noticeable. The fact that foam a) doesn't irritate my skin and b) dries so much faster makes it definitely worth using.

Susan's formula is the first thing I've used that has managed to make vellus hairs at my temples grow in length. Whether or not they'll become terminal remains to be seen. On the other hand, the main reason I started using it was because I hoped applying finasteride topically would prevent more hairloss (wasn't aiming for regrowth), which I'm not sure it has.

I got her formula in lotion form. On the first day of using it, I applied far too much and, due to the tretinoin content, it made my skin raw and painful. 3 months on, however, and I can apply as much as I want without any irritation. As Jazz mentioned, your body adjusts.

[Jazz1]

Hey Plan C quick question did your lotions arrive thick white cream? I just got my new package and all bottles seem to be thick and white in texture. I don't know if this is down to the freezing cold weather conditions from when being shipped to the uk.

The good part as my order was more 6 bottles due to adding another 3 bottles of Acetyl Glutsthione, I never got hit by customs this time .

What's your regime again?

[Jazz1]

Also, in what conditions do you store your bottles of susan's formula? I ask because mine started very thick but have gradually become runny.

Did the same bottle become runny?

[Plan C]

Hey Plan C quick question did your lotions arrive thick white cream? I just got my new package and all bottles seem to be thick and white in texture. I don't know if this is down to the freezing cold weather conditions from when being shipped to the uk.

The good part as my order was more 6 bottles due to adding another 3 bottles of Acetyl Glutsthione, I never got hit by customs this time .

What's your regime again?

Hi Jazz,

The lotion in both bottles I ordered was originally thick and white, in fact I remember expressing concerns about their viscosity a number of months ago in this very thread. Fortunately, they do become more runny over time.

My regime is:
100mg RU in ethanol/pg ED
Avodart EOD
Regaine foam once ED
Susan's lotion once ED
Revita + Jason Thin to Thick shampoo once ED

[Jazz1]

Hi Jazz,

The lotion in both bottles I ordered was originally thick and white, in fact I remember expressing concerns about their viscosity a number of months ago in this very thread. Fortunately, they do become more runny over time.

My regime is:
100mg RU in ethanol/pg ED
Avodart EOD
Regaine foam once ED
Susan's lotion once ED
Revita + Jason Thin to Thick shampoo once ED

Ok would you say the lotion works? As my new bottles arrived thick white cream texture, where as last time was lotion watery.

[Plan C]

Ok would you say the lotion works? As my new bottles arrived thick white cream texture, where as last time was lotion watery.

As mentioned earlier, I think it's adding length to vellus hairs at my temples.

[Jazz1]

As mentioned earlier, I think it's adding length to vellus hairs at my temples.

Thanks for the reply as I'm less panicky now due to the thickness of the mixture hope it works the same as my before lotion.

Oh has your hair stopped receeding? Your from the uk right? Good news I never got hit by customs this time and my order was more at cost.

[Plan C]

Thanks for the reply as I'm less panicky now due to the thickness of the mixture hope it works the same as my before lotion.

Oh has your hair stopped receeding? Your from the uk right? Good news I never got hit by customs this time and my order was more at cost.

Hi, I am from the UK and that's great news. I got a hefty customs charge last time.

I got my hair cut the other day and it's pretty clear the receding hasn't stopped. As a result, I started using ethanol/pg as my vehicle for RU, rather than Neogenic. Interestingly, I might be getting sides for the first time as a result. I've suffered from bad brainfog since making the switch, which isn't useful because I'm currently trying to write a uni assignment! On the other hand, it might mean that I've at last found a treatment that has some effect on me.

[Jazz1]

Yes tell me about it last time they charged me £18 by parcel force, Great sides mean less hair fall.

How do you apply your cream lotion? Seems like I have to start again as I was happy with the lotion watery mixture. I hope mine turns more watery as it was easier to use.

[Jazz1]

Right guys just an update from me and for anyone else finding it hard to measure the lotions who has a thicker white texture cream.

I had a 0.50ml measuring spoon at home, so 3 squirts from the pump will make 0.50ml, I'm going to be sticking with 4 squirts as that's enough to cover my temples and last me .

So to sum things up for the people who can not be bothered to measure the lotion etc and prefer to use the pump;

3 squirts will make 0.50ml
6 squirts will make 1ml.

[Plan C]

Yes tell me about it last time they charged me £18 by parcel force, Great sides mean less hair fall.

How do you apply your cream lotion? Seems like I have to start again as I was happy with the lotion watery mixture. I hope mine turns more watery as it was easier to use.

I basically just applied it directly to my temples and waited for it to dry. Even though it's really thick, it didn't tend to leave residue on my scalp so I recon it gets absorbed regardless.

And yeah, I agree that getting sides is sort of a good sign, especially because nothing else has seemed to affect me. But this brainfog is pretty bad so I hope it fades with time.

[Jazz1]

Hey the sides should fade over time as I had the same issue at the start, on the other hand does your temples suffer from the dreaded MPB itch?

Right guys i had Susan formulate me this mixture with added vitamin C so I could trial on myself, I'm using it on my temples to see if I notice any effect on my vellus hairs.

This article drew me into adding vitmain C, as Acetyl glutathione and vitamin E have huge impact on Hairloss from my research. I pray maybe one day I come across a cure to Help us all, that's my mission I'm constantly researching I believe one day a topical Mixture will block our genes allowing us to grow hair and be happy.

You have more than likely heard for many years about the benefits of having enough vitamin C in your diet, but did you know that this vitamin can also promote healthy hair growth and actually stimulate regrowth after hair loss?

Losing hair does not have to be a permanent thing, and there are many natural treatments for premature balding, including using vitamin C.

What is Vitamin C?
Vitamin C or ascorbic acid is an essential nutrient for humans. Its active form is L-ascorbate or L-ascorbic acid.

While Vitamin C is synthesized in almost all plants and animals, certain mammals including humans cannot synthesize the vitamin. Therefore, Vitamin C must be ingested in humans either through diet or supplements.

The recommended daily intake allowance of Vitamin C is still in contention but experts agree that a range of 45 mg to 400 mg is required and considered safe. However, a daily dose of up to 2 g is permissible.

Although scurvy is the main symptom associated with Vitamin C deficiency, hair loss is also a derivative sign of this deficiency. A low blood level of the vitamin is strongly correlated with dry and splitting hairs which, of course, quickly fall off.

Because Vitamin C is important for the synthesis of collagen, a deficiency of the vitamin leads to scurvy which is a presentation of weakened collagen on the skin.

In a similar manner, the production of tyrosine is dependent on the vitamin, and tyrosine is important for the maintenance of the structural integrity of hair strands and the cells of hair follicles.

Another known property of Vitamin C which can contribute to its ability to encourage hair regrowth is its action as an antioxidant. This is important in promoting skin health and preventing oxidative damage to the cells of hair follicles.

Since it also boosts the immunity, Vitamin C is a general champion of good health.

Facts about Vitamin C
There are many reasons why vitamin C is so good for us, and why it can be used to treat hair loss.

For one thing, vitamin C is water-soluble, so the body does not store it and accumulate too much in your system.

Here are some more interesting facts about this vitamin:

Vitamin C is loaded with anti-oxidant properties, just like vitamin E and zinc. These anti-oxidants reduce the damage that is caused by free radicals that are formed when food is converted into energy by the body. These free radicals can do a lot of damage to your hair, which is one reason why we need to make sure that we have enough of this vitamin in our diets.
When you have enough vitamin C in your system, you will have the nutrients you need to help produce collagen, which is necessary for healthy skin, bones, ligaments, muscles and blood tissues.
Vitamin C can also help reduce scar tissues and promote the healing of wounds. It is essential for healthy teeth and bones, and of course, hair.
The DKK-1 Link
The blood level of circulating androgens is important to the mechanism of hair loss. For example, a high level of DHT (dihydrotestosterone), a product of testosterone has been identified as the chief cause of androgenic alopecia.

Male hormones and their metabolites such as DHT bind to certain receptors of an important group of cells in the skin, the papilla cells. Papilla cells are chiefly responsible for transporting nutrients to other cells in hair follicles.

These cells play a key role in the events leading to balding or alopecia. When they are blocked by male hormones, they cannot effectively feed the hair follicles; therefore, hair production slows down.

To test whether Vitamin C has any positive effect in the reversal of hair loss, a group of Korean researchers from Kyungpook National University took some papilla cells from the skin of balding men and exposed them to a derivative of Vitamin C.

The derivative used was Ascorbic acid 2-phosphate which is used in many topical cosmetic products and which is converted to Vitamin C in the cell.

The idea to try Vitamin C salt on actual hair cells was born out of a prior research in which the group of researchers demonstrated that ascorbic acid 2-phosphate boosts hair growth.

To explain their findings, the researchers drew attention to the fact that androgens such as DHT are known to activate the dickkopf-1 gene which in turn produces a protein called DKK-1. The DKK-1 is sometimes called the baldness protein since it is found mostly in skin cells in people undergoing hair loss.

The study showed that as the DKK-1 protein level rose, the papilla cell population dropped. Just as these papilla cells died, the cells responsible for synthesizing the outer root sheath of hair strands stopped functioning. This quickly led to a sharp drop in hair growth and more hair loss.

However, when the Vitamin C salt was added to the papilla cells taken from balding people, the production of the DKK-1 protein was inhibited.

There was, however, an additional benefit: the vitamin also led to an increase in the production of IGF-1, a growth factor, in the papilla cells. Both of these effects lead to a reversal of hair loss.

Still, further studies are needed to determine what form of Vitamin C will provide the most benefit for people experiencing hair loss and whether topical preparations or supplements will better serve them.

Meanwhile, an important proof has been established directly correlating Vitamin C as effective in inhibiting the actions of androgens in relation to hair loss. That, in itself, is a major milestone since androgens, especially DHT, are known to a major cause of hereditary alopecia and hair loss in steroid users.

[LeonardoD]

How do you guys get it through customs? Tretinoi is an RX drug even in UK. Please explain - I am looking to purchase, but I doubt it will get through customs.

[losthair85]

Hey Jazz

I lost a lot of ground when I quit all hair loss meds for about 1.5 years. So I am about NW 3/4.

Yeah, I am looking for regrowth. Susan's lotion sounds promising based on the synergistic ingredients as you mentioned. Thanks for the tips on the hydrocort, I will include it in the mixture. I think I will try the DMI/PG mixture and see what happens.

And yes, I was actually following your posts a lot recently, and noticed that you use the Regenepure shampoo, I am going to order that too.

If I can think of anymore questions, I will let u know......many thanks!