Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[UK_]

Nope they are not praising HST they only say whats up right now. And i agree with Gho supporters because those people also push the envelope because this is a signal for surgeons to investigate further into regenerative processes.

While traditional FUT mills live from people like this SPanishDude who always waters every thread down with pokemon dummy research stuff

Fair enough - but everyone writes off UK Intercytex, their researchers still make comments about it being viable:

Intercytex worked on methods to take a biopsy from the back of the head, isolate the dermal papilla cells and expand them in culture, and then inject them into the balding areas of the scalp. The goal is to grow enough cells in vitro to freeze for later booster treatments. A phase 2 study in the UK showed some efficacy, but difficulties growing cells limited the commercial viability. Thanks in part to a souring economy, Intercytex sold the project in 2010 to Aderans Research Institute, based in Marietta, Georgia, which was working on a similar therapy.

“Everybody agrees that it's doable,” Kemp says. “The issue is getting the cells into the right location to talk to the keratinocytes and getting the keratinocytes into the right mood to listen.”

Source: Raising Hairs (2011)

They agree it can work... there are just issues that need ironing out...

[stillinHS1994]

Even if Histogen solves it(or solves it well enough) I still think the ones heading to Asia for treatment will be limited to the rich and the desperate. The others will save the money and wait for it to come closer to home. If it means I can stop Propecia sooner rather than later I'll gladly board an airplane though. I feel fine on it but I really hate using something that alters my hormones.

That said I might be underestimating our kind and we'll see new airline companies for the follicly challenge starting up with some clever slogan about shuttling us off to hairier life. On-flight movies limited to action flicks with Bruce Willis and Jason Statham on the way there, Brad Pitt and George Clooney romantic comedies on the way back. Oh sweet dreams.
Good night.

Haha frickin hilarious....I would agree with fin though...the stuff just creeps me out for some reason

[RichardDawkins]

Uk i cant say anything about trichoscience because i simply dont know anything about them and i didnt focus my research on them sorry.

[Thinning@30]

I know I'm beginning to sound like a broken record, but I really wish Histogen would come out and confirm that they have indeed started the trials, or at least provide us with updated timeline. My hair is looking pretty bad these days

I don't understand the radio silence. Even a few months ago they seemed to be demonstrating a refreshing and admirable level of openness and transparency. Why can't they tell us whether the next phase of their trials has started as planned?

[UK_]

Dont worry about sounding like a broken record... We would love an update!!! lol

[Curlybill99]

An update about anything on histogen would be great.. Or maybe another interview with spencer nd Doc ziering lol.

[UK_]

130,000 people have viewed this thread alone - how many of those would pay even 30k for this technology?

[UK_]

We report here that serially cultured adult papilla cells can induce the growth of hair when implanted into follicles which otherwise would not grow hairs. This finding presents an opportunity to characterize properties distinguishing the papilla cell population from other skin fibroblasts, and, more specifically, those which control hair growth. The eventual application of this work to human hair replacement techniques can also be envisaged.

That was in 1984... why has it taken so long to even try to see if it works?

[stillinHS1994]

130,000 people have viewed this thread alone - how many of those would pay even 30k for this technology?

I will be a broke college student just getting a degree when this stuff is supposed to come out but I will definitely find a way to pay for stuff like this...having hair wen I'm 30 would be worth it

[Losing_It]

Nobody should go through University worrying about hair loss. University is a great place, with so many things to experience. I was lucky enough to make it to 30 with all my hair. I use to to think bald men were lucky, since they didn't have to worry about maintenance. I guess I was wrong.

I am certain Histogen will be able to reproduce their pre-clinical results:

Lets look at the results:
1. 85 % of those treated showed hair growth
2. growth radiated 2mm from the injection point, so its well controlled
3. the new hair was maintained at the two year follow up suggesting that it should last at least one cycle.
4. existing hair were healthier than they were originally.
5. No adverse reaction even at the two year mark.

What I am wondering though is why 15% of the patients didn't respond to the treatment. Could it be that a higher dosage would be the key for those patients? Histogen knows that they sitting on a gold mine and that revenue in hair restoration would fund their more important cancer research.

Its all about reproducing their pre-clinical trials. If they achieve that, then we are all set.

[CAlex]

I remember reading or hearing Gail Naughton stating she was some ridiculously high percent (95%) or something that sure they can reproduce the pre clinical results.

I think so many people rag on the whole 5 years away heard that before thing because of so much past disappointments. I feel their pain. The difference between now and then was that was all over-hyped cure b.s. promises from rogaine and fin which we all know know is not even close to the case. All the other 5 year predictions were based off very early science that never panned out.

Histogen on the other hand has already created NEW hairs from scratch. Histogen may end up not even getting to market or working as good as many of us are hoping but AT least this is real science yielding real results so far. NOT just theory and 5 year predictions.

[Losing_It]

I completely agree with you Calex. This is a company that publishes in peer review journals. I think we can all agree that this is not Histogen's field, but merely trying to generate revenue for their other research. I have already accepted my fate in life, that i will loose my hair, so if HSC doesn't work out, oh well at least they tried. As long as I know that there are companies out there willing to pursue non-invasive techniques. I tried Propecia but after two months I couldn't deal with the sides anymore.

I am fairly confident though that Histogen will be able to reproduce their results. The fact that their are at least four companies pursuing similar techniques, means that we are really close to something big. Just a matter of who gets to market first to reap the rewards.

[Cory]

Really hope that Histogen comes 2014 together with Follica and Replicel and puts end to baldness.

[stillinHS1994]

Really hope that Histogen comes 2014 together with Follica and Replicel and puts end to baldness.

Haha I think its safe to say we all hope for that

[MrRyan]

So i have read this thread through and it seems as though we can expect at least 50 hairs cm2 (if it works ) from Histogen, now i just looked at my scalp out of interest, i'm in the very early stages of hair loss and only i can notice it at this point although i'm not sure how much longer i will get away with it for. Anyway i took a rough count of my hair count and it doesn't seem like there are that many hairs per cm2, now a lot of you say that 200 cm2 is the normal amount on the scalp that seems like a hell of a lot to me am i missing something here or can you only count hairs properly with certain equipment.

And i know it's not very scientific, but i just drew a cm2 filled it with 200 dots and the thing was nearly coloured in, that would equate to a very very dense head of hair, even 50 seemed to fill in very nicely, please correct me if i'm way off i'm just interested thats's all.