2015 outlook.

[rdawg]

I know it's a rough time right now with not much news coming in. We are in the middle of trials for a lot of drugs, and waiting for other companies to start trials as well. It may seem as though there is nothing on the horizon, and in 2012 we thought we would have had Aderans and Histogen here by now for sure, but hey, such is life.


To keep your heads up, and look at this position rationally, we are the luckiest sufferers of AGA to date, in regards to research being done and improvements being made.

1. Transplant results are getting better and better, and within the next two years we will have a scarless, minimally invasive procedure, with better yield than we have ever seen and MAYBE regeneration. I personally believe we will see it to at least some extent (hopefully Dr. Wesley's changes to his instrument still have him focusing on it, because the science IS there.)

2. Bim, this product could be to the market REALLY soon. They just finished phase IIb trials, in which they were using dosages 10x higher than previous research used. Joe from stat, and Spencer both have heard that the results are promising and it could have people coming off propecia and minox. (that's just rumors though, wait to see results by the end of this year/beginning of next)

3. SM, this drug came out of NOWHERE. No one had a single clue that it was being tested in Australia and it is now in the middle of a phase II trial involving over 300 patients in the US. It's focusing on the WNT pathway, and they are only testing it on nw4+ patients.

4. CB, in the middle of phase II POC trials, testing at 5% twice daily and it is supposed to be a finasteride or better without side effects.

5. Replicel, has major backing and they are testing an improved formula on a number of patients, probably at least 3 years out though.

6. Histogen, they haven't come out and said it, but I personally believe they are dead because they were supposed to start phase IIb by now. Reality of it is, their results probably weren't good enough to get the money as investors see other drugs/treatments that have more potential... ex: you don't buy a 2015 ford f250 the day before the 2016 model, that has been redesigned, is going to be released

7. Kythera (setipiprant) cotseralis work going to be tested in trials. This drug is going straight into phase II testing and only needs phase II then Phase III to be released..so it has potential to make it out within 3 years if the results are promising. This will be a good indicator of if the pgd2 pathway is a major factor and will pretty much be the start/end of cots and his work.

8. PRP therapy. It's only getting better, as doctors are gaining more knowledge on growth factors and concentrations..etc. the treatment is improving. I have seen some amazing results in some patients, it just needs to become more consistent.

9. Follicept, may or may not be anything..but we will know in a few months.

10. research continues to advance on bioengineering follicles and finding a real cure. It may be 50 years, or it may be 5 years...but at the rate our knowledge on the subject is advancing..I think we will see a real cure sometime in the next 15 years. There are more research teams working on this than we know, and we are gaining knowledge faster and faster.

11. AA has been cured by accident. You never know what the next day brings..the same could happen for AGA.

Interesting looking back on this the progress we've made in only a few months, makes me even more excited for 2016!!

both SM and Histogen created new terminal hairs where there was none or very very little hair in that area. That alone is something we have not seen at all until 2015, some people may still have problems, but that is an incredible breakthrough in it's own right. Not full-out cures, but massive steps forward.

On top of that BIM showed higher efficacy than Minoxidil, which in it's own right is a great step forward beyond the archaic drugs, not an amazing product, but something that gives us an effective option for early-mid sufferers.

on top of that Replicel is finally moving forward with trial, CB and SETI will likely update us very soon!

Not only that but research towards a complete cure is definitely taking steps forward with them making breakthroughs with the culturing of cells(this stuff goes over my head), this stuff is likely 5-10 years away, but to know they are getting very close brings alot of hope.

All in all it's been a fantastic year, and we will likely get even more products next year, I expect alot of news in Q1, followed by a bit of the usual silence in the spring, but it's only going to get better from here!

[jamesst11]

Setipiprant > Pilofocus > Anything we have today.

expand this equation please and some rationale would be helpful... where exactly is histogen in this?