Histogen?s HSC Complex - An In Depth Discussion

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  • tbtadmin
    Administrator
    • Sep 2008
    • 982

    Histogen?s HSC Complex - An In Depth Discussion

    The hair loss world is buzzing about Histogenís small, but impressive pilot clinical trial. Despite some much talked about setbacks, it looks like itís “all systems go” for the San Diego based startup.Last year Histogen was forced to layoff thirty six of itís employees after itís fundraising efforts were stifled when a rival company located [...]

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  • KeepTheHair
    Senior Member
    • Mar 2010
    • 1215

    #2
    Great, segments!


    I am listening to this right now. Thanks!

    Comment

    • KeepTheHair
      Senior Member
      • Mar 2010
      • 1215

      #3
      Never too much discussion, ey?

      Great stuff. You guys seem hyped up... I can't wait for the future.

      I will have to just, keepthehair

      Comment

      • KeepTheHair
        Senior Member
        • Mar 2010
        • 1215

        #4
        Wow, just when the conversation got interesting it cuts out! lol

        6 months? or anything soon? That would be amazing. Think of that!


        I guess its just a dream. Damn, you overexcited me lol

        Comment

        • Fixed by 35
          Senior Member
          • Mar 2010
          • 618

          #5
          I'd love to become actively involved with this company. Don't suppose they need a corporate secretary who'll take a pay cut in return for share options and a try of the formula?

          Comment

          • KeepTheHair
            Senior Member
            • Mar 2010
            • 1215

            #6
            I would scrape their floors and polish their shoos for years if I could get that treatment :P

            Comment

            • TanCas
              Junior Member
              • Apr 2010
              • 7

              #7
              I have a few questions about Histogen:

              1. How many injections were administered (2009 trial, on 25 subjects)?

              2. Could the drug be used successfully in areas that have received hair transplantation?

              3. Would the directions of new hairs need to be controlled? If so, how would this be accomplished?

              4. Would newly-developed hairs risk "interfering" with existing follicles (i.e., crowding the space and altering the natural directions of prior hairs)?

              5. If one injection covers even a reasonable amount of area (i.e., greater than of a few tightly-packed follicular units), how would one prevent hair from growing where it's not wanted (e.g., on the forehead, if the drug is used near the anterior scalp)?

              6. Would the drug produce hair anywhere it were administered, even if the area never grew hair, previously (e.g., palms)?

              Thank you.

              Comment

              • Fixed by 35
                Senior Member
                • Mar 2010
                • 618

                #8
                They claimed to have one injection in the year.

                As far as I've heard, Histogen reactivates dormant cells. That should answer 3-6.

                I'm not sure about the second question, that would be interesting to know.

                Comment

                • KeepTheHair
                  Senior Member
                  • Mar 2010
                  • 1215

                  #9
                  It also stimulates growth of entirely new cells.

                  Comment

                  • TanCas
                    Junior Member
                    • Apr 2010
                    • 7

                    #10
                    Right, this idea of stimulating the growth of hair where previously there was none, is what confuses me to how the process would be controlled — its effects strictly contained to where they are desired, prevented from affected areas in which one wants no growth.

                    Also, I'm concerned new hairs might push around existed ones such the overall appearance is cosmetically unpleasant.

                    Even if Histogen's product works, I think at least these two points must be addressed if one is to be hopeful of its practical utility.

                    Comment

                    • Fixed by 35
                      Senior Member
                      • Mar 2010
                      • 618

                      #11
                      I think Histogen just provides wnt signalling to create new hair. I don't think new cells are created, that's another company.

                      Comment

                      • KeepTheHair
                        Senior Member
                        • Mar 2010
                        • 1215

                        #12
                        Well I meant new hair. Hair consists of cells :P

                        Comment

                        • Fixed by 35
                          Senior Member
                          • Mar 2010
                          • 618

                          #13
                          Sorry, I meant I think it re-activates the follicles you had from stem cells, it doesn't create brand new ones.

                          Comment

                          • KeepTheHair
                            Senior Member
                            • Mar 2010
                            • 1215

                            #14
                            Ah I see. Well who knows. I think it might be making a completely new follicle from nothing perhaps. Since a dead follicle is probably.....gone.

                            We will see.

                            Comment

                            • Fixed by 35
                              Senior Member
                              • Mar 2010
                              • 618

                              #15
                              I thought Histogen re-activated the dead follicle, effectively creating 'new hair' from the stem cell.

                              The only concern about the treatment I do have is the possibility that it could be too good. I mean, I want my hair back, but I'm not sure I want a juvenile hair line!

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