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To keep a Dieffenbachia healthy, wipe its leaves regularly to remove dust and improve light absorption. Rotate the pot every few weeks so the plant grows evenly on all sides. Trim off yellow or damaged leaves to encourage fresh growth and inspect the foliage for pests such as spider mites or mealybugs. Because the plant's sap can irritate the skin and is toxic if swallowed, wear gloves when pruning and place it safely out of reach of children and pets.