Spironolactone, Revivogen, and other Anti-Androgens

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  • DepressedByHairLoss
    Senior Member
    • Feb 2011
    • 854

    Spironolactone, Revivogen, and other Anti-Androgens

    I'm getting off of Propecia due to side effects and I was wondering if Spironolactone cream and Revivogen were effective anti-androgens and alternatives to Propecia. Anyone who used these two products, your input would be greatly appreciated. Thanks!
  • PatientlyWaiting
    Senior Member
    • Jan 2011
    • 1637

    #2
    Spiro cream is the alternative to Finasteride. I heard it's less effective though, but it does not causes any sides. Never tried it though.

    I've read good things about Tricomin which uses copper peptides but I have never used any of these so I can't tell you how effective they are. It's an alternative to Minoxidil.

    You can also try Saw-Palmetto and Beta-Sitosterol.

    Those are the only alternatives I know of. You should read customer reviews on Revivogen and Tricomin and see from there.

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    • Follicle Death Row
      Senior Member
      • May 2011
      • 1058

      #3
      If you're not already using Nizoral shampoo 3 times a week you might consider that. Ketoconazole is the active anti androgen in it so it does do some good.

      Comment

      • lost.hair.lost.youth
        Junior Member
        • Feb 2011
        • 12

        #4
        Originally posted by Follicle Death Row
        If you're not already using Nizoral shampoo 3 times a week you might consider that. Ketoconazole is the active anti androgen in it so it does do some good.
        Are you sure about that?

        From http://en.wikipedia.org/wiki/Ketocon...nism_of_action
        As an antiandrogen, ketoconazole operates through at least two mechanisms of action. First, and most notably, high oral doses of ketoconazole (e.g. 400 mg 3x/day) block both testicular and adrenal androgen biosynthesis, leading to a reduction in circulating testosterone levels.[17] Ketoconazole produces this effect through inhibition of cytochrome P450 and 17,20-lyase, which are involved in the synthesis and degradation of steroids, including the precursors of testosterone. Due to its efficacy at reducing systemic androgen levels, ketoconazole has been used as a treatment for androgen-dependent prostate cancer.[18] Second, ketoconazole is an androgen receptor antagonist, competing with androgens such as testosterone and DHT for androgen receptor binding. This effect is thought to be quite weak, even with high oral doses of ketoconazole.[19]
        I'm also very interested in anti-androgens used at the topical level.

        Comment

        • Thunderbass
          Junior Member
          • Jul 2011
          • 25

          #5
          Topical Spiro did nothing except make my head smell bad. It has an unpleasant odor.

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