It's more complicated than that. The real worry would be observing the problem from a neuromuscular standpoint. Reducing serum DHT by 65-70% is not the best idea as it will have an impact on neurosteroids and central nervous system signalling. To what degree? Who knows. Could very well depend on the individual.
Here's one small article I thought was interesting:
Anways it doesn't matter about 5AR1 or 2 being in muscle or not as DHT is deactivated by an enzyme called 3alpha-hydroxysteroid reductase. In other words T is always the active androgen in muscle. However it's neurological adaptions in exercise where DHT plays a big role. Neural output can be compromised.
Here's one small article I thought was interesting:
Anways it doesn't matter about 5AR1 or 2 being in muscle or not as DHT is deactivated by an enzyme called 3alpha-hydroxysteroid reductase. In other words T is always the active androgen in muscle. However it's neurological adaptions in exercise where DHT plays a big role. Neural output can be compromised.
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