RepliCel News - Shiseido & RepliCel Announce Agreement

[TravisB]

To be honest I have a hard time believing it will be something very effective, based on their May 2012 Phase I/IIa results, which can be found here - http://www.replicel.com/wp-content/u...im-Results.pdf

[KO1]

60% response seems to be the magic number. ARI gets 60% response, Replicel gets 63%, Nigam is getting 50-70%. I wonder why.

[TravisB]

What's troubling is that subjects who received PLACEBO also got increase in hair density (37% of subjects as opposed to 63% treated with DSC cells), ROFL. What's going on?

[moore]

New article...were they pushed to release this informations because of the recent articles about Jahoda/Christiano discovers?

http://www.vancouversun.com/health/Stem+cell+technology+work+search+hair+treatments/9086893/story.html

[Artha]

New article...were they pushed to release this informations because of the recent articles about Jahoda/Christiano discovers?
http://www.vancouversun.com/health/S...893/story.html

Yeah... I think the race for a cure is ON!!

[Thinning87]

thanks for posting, although the article doesn't say anything new

[Artha]

What that Jahoda/Christiano discovers that we didn't know already?

[Jazz1]

What ever these geeks are doing I hope something comes out soon!!!

[Artha]

The Vancouver Sun article is new and legit as posted on the official Replicel twitter account!

https://twitter.com/RepliCel

[Artha]

Replicel explain their procedure in this new panel.

[Sogeking]

The problem lies in the 6th step. They are anticipating that this cells will migrate to the dormant ones. And even if they do, there are no growth factors like fibroblasts to kickstart basically to induce this cells to start growing the new hair. Cells on their own, without us knowing which gen can induce their development into a hair follicle, won't start producing new hair. Well at least not in any significant amount.

[moore]

thanks for posting, although the article doesn't say anything new

What that Jahoda/Christiano discovers that we didn't know already?

Yeah sorry I wrote in a hurry. My point was, I thought Replicel representatives felt like they had to say something after this article.

The problem lies in the 6th step. They are anticipating that this cells will migrate to the dormant ones. And even if they do, there are no growth factors like fibroblasts to kickstart basically to induce this cells to start growing the new hair. Cells on their own, without us knowing which gen can induce their development into a hair follicle, won't start producing new hair. Well at least not in any significant amount.

Well I used to be quite positive about the Replicel method.
Now I wonder about 6th step myself. And my big question remains the same:
->How is something injected in the scalp, apparently in a random spot, supposed to know where to go? How is it supposed to reach exactly certain tissues?<-
And, even more:
How is the same compound supposed to be able to both stimulate old follicles as well as instigate the creation of new ones? (folliculogenesis?)
Maybe I'm just talking of stuff I don't know anything about. Some people spend years just to be able to use the right scientific terminology. I did not, and still I try to elaborate on matters which defied research for decades.

[TheSwingingGate]

How is the same compound supposed to be able to both stimulate old follicles as well as instigate the creation of new ones?

http://www.faqs.org/patents/app/20130204238

This Follica patent describes a similar process of stimulating and creating new follicles. Interesting.

[crafter]

This on Replicel's website

http://www.replicel.com/a-cure-for-baldness-stem-cell-researchers-race-to-regenerate-follicles-from-hair-resistant-to-loss/

This quote is interesting -

"But RepliCel’s plan isn’t to bring its cell cloning all the way to market, Hall says. Rather, it wants to prove the effectiveness of the technology in the hopes it will be purchased by another company."

[Thinning87]

How is that interesting