Study by Dr. Cole about Acell/PRP and Donor Regeneration. Very good results!

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  • joachim
    Senior Member
    • May 2014
    • 559

    #16
    i think dr. cole is totally right with his diameter/follicle bisecting statement. it was already raised in another thread that bisected follicles, even if both halves start to grow, the diameter was finer. and all in all, with bisecting follicles the chance for surviving follicles is smaller, and you would end up in less than one total follicle, like dr. cole mentioned.
    thus, only if dr. wesley can show donor regeneration with the same diameter than before, then it can be success, otherwise it's doomed to fail. to me, the only advantage of pilofocus is that you don't see any white dots.
    but if dr. cole achieves similar results and much better healing properties with acell, then it's a good deal and there's no need to adopt a new surgical instrument. all in all, i don't really have much hopes for pilofocus. the marketing was good though. it was hyped up by some users here so that everybody got excited.

    however, i'm looking forward to the donor regeneration test of dr. cole.
    if that fails as well, then i think we can all agree that donor regeneration will never ever happen. too many tried and failed already.

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    • hairlosskills
      Member
      • Sep 2014
      • 51

      #17
      Dr cole do you offer prp to patients who had surgery else where as a means of maintaining hair loss...and or promoting hair growth for the top of the scalp AND in the DONOR?
      -thanks in advance

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      • hairlosskills
        Member
        • Sep 2014
        • 51

        #18
        To clarify what i said above, im experiencing some sort of telogen efflivium or diffusing in the donor as well as on the sides and my sideburns . Have you used your prp with this type of loss?

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        • John P. Cole, MD
          Senior Member
          • Dec 2008
          • 401

          #19
          We've had pretty good success with PRP. We measure the cross sectional trichometry before the procedure and after. We recently had a woman who increased from a 60 to about 98 on her cross sectional trichometry with PRP one year later. That was a pretty good response. I think that not all respond probably due to epigenetics. There are questions that remain to be answered such as the optimal needle, the optimal depth to inject, the optimal way to activate the PRP, how often to inject, and the optimal hematorcrit. Everyone seems to be all over the place in terms of what they are doing. I like a 5X concentration, a 25 to 27 gauge needles, a 2% hematocrit, injection every 6 to 12 months, and injection in the dermis. i think the current recommendations in Europe are to repeat in one month and then every 3 months. i think this might be a little much, but maybe. Maybe we should repeat in one month and then every 6 months. It needs to be studied.

          I think we are way off in terms of a panacea with Acell. That's why I'm looking at the smaller particles from Amniotic membrane. I'm hoping. I worry that some of the Acell leaks out of the extraction sites. I wonder if injecting would improve the results.

          Maybe Acell will help the hair diameters from the bisecting that Dr. Wesley recommends. As usual, there are more questions than answers.

          I do think PRP can help the sides of the head too. I've seen donor areas improve with PRP perhaps because the PRP drains due to gravity. I typically measure the cross sectional trichometry in the front, top, crown, and donor areas. Sometimes i measure the CST above the ears. When there is a strip scar, I measure both above and below the scar. We see some interesting responses to medical therapy and surgery. It's a great test. More physicians should use it. It's the most sensitive way to see if there has been a positive change.

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          • willy
            Member
            • Feb 2012
            • 31

            #20
            I can't wait for Dr. Cole's regeneration test on Agahi. If this happens it will be, in my opinion, the most exciting subject on this forum.

            Sorry if this has already been answered but will the test also measure the quality of the extracted follicles as well as the regenerated ones? Does that make sense? For example, HASCI clinic would show impressive regeneration but it's because they only take out partial follicles and the recipient quality is that of a "half hair".

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            • FearTheLoss
              Senior Member
              • Dec 2012
              • 1581

              #21
              So have you set this up dr cole? We don't want to let this pass.

              FTL

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              • James Bond
                Junior Member
                • Oct 2014
                • 2

                #22
                Originally posted by John P. Cole, MD
                One must follow a minimal depth extraction protocol in order to get follicle regeneration.
                Hi Dr. Cole. I'm not surprised about the need to leave as much tissue behind in the donor as possible while still taking enough to support the growth of the extracted follicles. I'm interested in whether the new hairs that grow in the donor initially emerge from the skin with a thin tapered tip or if they emerge with a full thickness clipped tip.

                Thank you

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                • bananana
                  Inactive
                  • Feb 2012
                  • 524

                  #23
                  Hi everybody,

                  any update on this? I'm highly interested in this subject.

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                  • ss1980
                    Member
                    • Apr 2011
                    • 67

                    #24
                    This will be interesting to see how it turns out. Dr Cole is the one a I have trust in, I like his pragmatic approach to the subject of follicle regeneration.

                    Taking out all follicle from 1x1 cm area would be ultimate test and in case nothing grows you can always cover that spot by extracting 40-50 grafts from other donor areas and it will look fine. Hence, bald square wont be permanent.

                    There has been so many claims of donor regeneration over the past couple of years but somehow no one could prove anything which I find strange. Maybe its marketing trick designed to generate publicity, any publicity is good publicity


                    Do have any updates on this case, guy who volunteered?

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                    • willy
                      Member
                      • Feb 2012
                      • 31

                      #25
                      Any updates on this 1X1cm test ? Agahi? Dr. Cole?

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