Sensory hair cells regenerated, hearing restored in mammal ear

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  • clandestine
    Senior Member
    • Aug 2011
    • 2002

    Sensory hair cells regenerated, hearing restored in mammal ear

    "Researchers demonstrate for the first time that hair cells can be regenerated in an adult mammalian ear by using a drug to stimulate resident cells to become new hair cells, resulting in partial recovery of hearing in mouse ears damaged by noise trauma.

    Hair cells are the primary receptor cells for sound and are responsible for the sense of hearing," explains senior author, Dr. Albert Edge, of Harvard Medical School and Mass. Eye and Ear. "We show that hair cells can be generated in a damaged cochlea and that hair cell replacement leads to an improvement in hearing.
    "

    Hearing loss is a significant public health problem affecting close to 50 million people in the United States alone. Sensorineural hearing loss is the most common form and is caused by the loss of sensory hair cells in the cochlea. Hair cell loss results from a variety of factors including noise exposure, aging, toxins, infections, and certain antibiotics and anti-cancer drugs. Although hearing aids and cochlear implants can ameliorate the symptoms somewhat, there are no known treatments to restore hearing, because auditory hair cells in mammals, unlike those in birds or fish, do not regenerate once lost. Auditory hair cell replacement holds great promise as a treatment that could restore hearing after loss of hair cells.
  • clandestine
    Senior Member
    • Aug 2011
    • 2002

    #2
    "This is the first demonstration of hair cell regeneration in an adult mammal. "We're excited about these results because they are a step forward in the biology of regeneration and prove that mammalian hair cells have the capacity to regenerate," Dr. Edge said."

    Mice, though. But still.

    Comment

    • hellouser
      Senior Member
      • May 2012
      • 4419

      #3
      Would be nice if they found a cure for Tinnitus...... I havent heard silence in a long time.

      Comment

      • garethbale
        Senior Member
        • Apr 2012
        • 603

        #4
        In a mouse?

        Oh great...

        Comment

        • clandestine
          Senior Member
          • Aug 2011
          • 2002

          #5
          Yeah, sorry. Pretty sure it's mice. But it's a new article and I felt it relevant.

          Comment

          • tonypizza
            Member
            • Jul 2011
            • 47

            #6

            Comment

            • garethbale
              Senior Member
              • Apr 2012
              • 603

              #7
              Originally posted by clandestine
              Yeah, sorry. Pretty sure it's mice. But it's a new article and I felt it relevant.
              haha, no need to apologise, just that nothing ever comes from these 'breakthroughs'

              Comment

              • fred970
                Senior Member
                • Nov 2009
                • 922

                #8
                Well, now they're going to cure deafness and blindness before baldness!

                Comment

                • DepressedByHairLoss
                  Senior Member
                  • Feb 2011
                  • 854

                  #9
                  Originally posted by fred970
                  Well, now they're going to cure deafness and blindness before baldness!
                  Actually, they probably won't cure a damn thing. Just like with hair loss discoveries, they'll test these things on mice a thousand times, but not do a damn thing to make it applicable to humans.

                  But thanks for bringing this article to my attention, clandestine. We need regenerative procedures like these to cure hair loss, and not these surgical procedures over and over again.

                  Comment

                  • clandestine
                    Senior Member
                    • Aug 2011
                    • 2002

                    #10
                    Originally posted by DepressedByHairLoss
                    But thanks for bringing this article to my attention, clandestine. We need regenerative procedures like these to cure hair loss, and not these surgical procedures over and over again.
                    No worries, dbhl. I know you're entirely interested in the whole regenerative, stem cell thing. I am as well, and am in agreeance that research and appropriate product development in this field could not come faster /sooner.

                    Comment

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