Histogen update from the ISHRS 2012

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  • ammin
    Member
    • Sep 2012
    • 74

    #31
    @desmond 84

    Not only will we have Histogen come to market in 2016, but CB will most likely come to market that year as well, as is manifest by Chris Tanner's response to my email that I posted in the CB thread

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    • ammin
      Member
      • Sep 2012
      • 74

      #32
      and **** 2020. He is a pseudo scientist that comes across as bright when you first read his posts but upon gleaning some knowledge myself I have lost all respect for him. In some of his posts, he was struggling with basic arithmetic.

      Ignore him. Look at the pictures Histogen's released and come to your own conclusions. Reading his meritless ill-conceived theories can discourage the uninitiated but not anyone else who is steeped in hair loss science in the slightest.

      Comment

      • 2020
        Senior Member
        • Jan 2012
        • 1513

        #33
        You must be in a minority who think these were good results. Histogen not being transparent doesn't help either.

        Comment

        • ammin
          Member
          • Sep 2012
          • 74

          #34
          Money talks bro. You are operating anonymously from behind a computer screen conceiving junk theories and admittedly can't afford a hair loss regimen that costs more than $80 whereas Histogen is collaborating with accomphlished dermatologists and scientists while raising millions of dollars to take their research endeavors to the next level.

          This is America. Markets are efficient as much as they can be on the planet. If Histogen did not offer a ground-breaking solution to our hair loss problems , they wouldn't be able to raise money for their expensive "science experiments"
          .

          The projects would be abandoned and the parties involved would go pursue other endeavors.

          Comment

          • ammin
            Member
            • Sep 2012
            • 74

            #35
            Heres an exercise for you to undertake- Propose one of your Sh***y hair loss cures as the basis for a dermatological start up, get a team together and see if you can raise an iota of interest from Venture Capitalists .

            I will guarantee you wouldn't raise a cent because there's only so much you are intellectually capable of besides taking a sh*t. I will happily transfer a $1000 to Spencer Kobren which you can keep if you can prove to me your ability to raise capital from investors to make my guarantee more credible.

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            • 2020
              Senior Member
              • Jan 2012
              • 1513

              #36
              Originally posted by ammin
              Money talks bro. You are operating anonymously from behind a computer screen conceiving junk theories and admittedly can't afford a hair loss regimen that costs more than $80
              is that a joke? That is my regimen and I am taking it.

              Originally posted by ammin
              whereas Histogen is collaborating with accomphlished dermatologists and scientists while raising millions of dollars to take their research endeavors to the next level.
              ??? plenty of companies who raised a lot of money fail eventually.

              Originally posted by ammin
              This is America. Markets are efficient as much as they can be on the planet. If Histogen did not offer a ground-breaking solution to our hair loss problems , they wouldn't be able to raise money for their expensive "science experiments"
              .

              The projects would be abandoned and the parties involved would go pursue other endeavors.
              yes, that's why they're doing their trials in Singapore... Replicel raised money too. Are you happy with their results?

              I want them to succeed but their recent results have been disappointing and it's not just me. I'm just being realistic.

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              • rdawg
                Senior Member
                • Jun 2012
                • 996

                #37
                Originally posted by 2020

                I want them to succeed but their recent results have been disappointing and it's not just me. I'm just being realistic.
                No you're not, you're being pessimistic. Realistically Histogen has caused some growth, minor in some patients and better in others.

                There are multiple avenues histogen could go down and we could end up with better results(what happens as more time goes by, what happens if they add more injections later? etc.)

                You make it sound like this is terrible, useless stuff that won't help anyone, it's not AMAZING, it's not a full-cure(at least currently), but it is better than anything on the market, it's shown results and it's still early in the trials(we're talking about a product 3-4 years away with at least a couple years of trials/testing left).

                We dont even know if this will react even better with say a DHT inhibitor(RU, Fin, etc.) or with PGD2, or with minoxidil or with Bitamoprost. Man just mentioning that stuff we have so many options coming up I dont know how anyone can be negative right now.

                Comment

                • 2020
                  Senior Member
                  • Jan 2012
                  • 1513

                  #38
                  and I've asked you that: what other variables could they possibly change? More injections? How many injections could they possibly make? 1000?

                  not interested in wrinkles from minoxidil or eye color change from bimatoprost. It's all or nothing from HSC.

                  Comment

                  • Dan26
                    Senior Member
                    • Jul 2012
                    • 1270

                    #39
                    2020

                    1) Reduce inflammation, reduce histamine response, inhibit pgd2 and increase pge2.

                    +

                    2) Histogen (or something similar to it)

                    +

                    3) Androgen Control *

                    =

                    Halt hair loss AND regrow.

                    If you disagree, explain why please. I don't share a similar view in your expectations of histogen, not because I'm impressed by what histogen has showed us, but because what a few people who used something similar told me.

                    Comment

                    • Dan26
                      Senior Member
                      • Jul 2012
                      • 1270

                      #40
                      Originally posted by 2020
                      and I've asked you that: what other variables could they possibly change? More injections? How many injections could they possibly make? 1000?

                      not interested in wrinkles from minoxidil or eye color change from bimatoprost. It's all or nothing from HSC.
                      Why is it 'all or nothing' with HSC? Obviously HSC alone cannot fix the problem!!

                      Comment

                      • The Alchemist
                        Senior Member
                        • Mar 2011
                        • 261

                        #41
                        Originally posted by 2020
                        and I've asked you that: what other variables could they possibly change? More injections? How many injections could they possibly make? 1000.
                        The male patient in their photos appears to be quite old and has fairly advanced AA. They made 20 injections on him. The efficacy of the injections is known to reside within a tight radius of the injection site. Based on that alone i wouldn't expect to see massive hair regrowth. However, He has easily visible, terminal hairs regrowing within a 6 month time frame. That type of result is unparalled by any treatment we have to date. You take a 50 plus year old man with advanced alopecia and you can feed him propecia ad nauseum every day and you will not see anything even close to this in a 6 month time frame. The same with minoxidil.

                        20 injections is nothing. People get 10-20 freaking botox injections into the most sensitive portions of their faces multiple times per. So long as it's safe, there is absolutely no reason they can't do a 100-200-500 or a thousand or more injections. Whatever the %&^* it takes to get a result. Any pain associated with this type of approach (though it's probably no worse than dermarolling your head) could be handled with local anaesthetia.

                        I understand your critical approach. There's been enough garbage and over hype through the years to make even the most optimistic person cynical. But, these results are a big step forward. I only wish they were proceeding faster...i need the help now, not in 4 years.

                        Comment

                        • Dan26
                          Senior Member
                          • Jul 2012
                          • 1270

                          #42
                          Originally posted by The Alchemist
                          The male patient in their photos appears to be quite old and has fairly advanced AA. They made 20 injections on him. The efficacy of the injections is known to reside within a tight radius of the injection site. Based on that alone i wouldn't expect to see massive hair regrowth. However, He has easily visible, terminal hairs regrowing within a 6 month time frame. That type of result is unparalled by any treatment we have to date. You take a 50 plus year old man with advanced alopecia and you can feed him propecia ad nauseum every day and you will not see anything even close to this in a 6 month time frame. The same with minoxidil.

                          20 injections is nothing. People get 10-20 freaking botox injections into the most sensitive portions of their faces multiple times per. So long as it's safe, there is absolutely no reason they can't do a 100-200-500 or a thousand or more injections. Whatever the %&^* it takes to get a result. Any pain associated with this type of approach (though it's probably no worse than dermarolling your head) could be handled with local anaesthetia.

                          I understand your critical approach. There's been enough garbage and over hype through the years to make even the most optimistic person cynical. But, these results are a big step forward. I only wish they were proceeding faster...i need the help now, not in 4 years.
                          Do you know if they use traditional syringes to inject? I would think mesotherapy guns would be better?

                          I can't wait four years. I will infiltrate Histogen's headquarters and take their solution if I have to. I will call China, Korea, Russia; any lab that can replicate this hair stimulating complex for me. Stop at nothing bald brothers, stop at nothing.....

                          I think Highlanders' posts are starting to rub off on me.

                          Comment

                          • 2020
                            Senior Member
                            • Jan 2012
                            • 1513

                            #43
                            Originally posted by Dan26
                            Why is it 'all or nothing' with HSC? Obviously HSC alone cannot fix the problem!!
                            why not? As I said before: the difference between 20% hair growth and 20,000% growth is the number of injections.

                            Comment

                            • yeahyeahyeah
                              Senior Member
                              • Nov 2011
                              • 1776

                              #44
                              Originally posted by 2020
                              why not? As I said before: the difference between 20% hair growth and 20,000% growth is the number of injections.
                              Maybe you need to give them a chance, they are still in phase 1

                              Comment

                              • rdawg
                                Senior Member
                                • Jun 2012
                                • 996

                                #45
                                Originally posted by 2020
                                and I've asked you that: what other variables could they possibly change? More injections? How many injections could they possibly make? 1000?

                                not interested in wrinkles from minoxidil or eye color change from bimatoprost. It's all or nothing from HSC.
                                Pretty weird to expect all or nothing.

                                I mean using the big 3 NOW is good enough to gain a lot of hair for people, a solution like HSC will only add to the list of posibilities, the list of people who could be positively affected.

                                What other variables? I just told you and even Dan26 just mentioned, combining these products could produce awesome bald reversing results?

                                Are you ever going to be positive. And what's with the assumptions on Min and Bim, never heard of wrinkles from Minoxidil.

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