Cetirizine

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  • Campbell22
    Member
    • Feb 2013
    • 42

    Originally posted by Conpecia
    Vehicle is just Cet and water. Really simple. Anyone who's on Minox should consider adding it if the good news keeps coming.
    Thanks. That's exactly what I will do as I already have everything.

    Comment

    • Conpecia
      Senior Member
      • Sep 2011
      • 904

      Originally posted by Campbell22
      Thanks. That's exactly what I will do as I already have everything.
      Me too. But let me caution you: one guy said he burned a whole NW off his hairline using Cet that didn't grow back (not sure if he was using the right vehicle, nor do I think he stayed with it long enough to recover what he shed). But seeing as how you're on some other stuff, I'd wait until we get some more positive reports before adding it, honestly. One or two dudes claiming regrowth is great news, but it's by no means conclusive. We need like 20 people with pics over a year long period. I'd stick with your current regimen until we get more good news. Just lookin out for you man.

      Comment

      • eqvist
        Member
        • Aug 2011
        • 96

        It would be interesting if we had people on fin and minox adding this!

        Comment

        • Conpecia
          Senior Member
          • Sep 2011
          • 904

          I'm bumping this because someone brought up PGD2 blockers (which CET is) on ************ forums and four or five guys immediately responded that CET has stopped their hairloss. These guys have been on CET for something like 8-9 months by now, I remember when they first started way back in October/November of last year. The PGD2 theory seems more and more legitimate. Also, for those worried about indo/chromo sides, CET may be a safer alternative. And it's MUCH cheaper.

          The thread:

          http://www.****************/interact...-pdg2-blockers

          Comment

          • thechamp
            Senior Member
            • Jan 2011
            • 1763

            So we just bang a few Zyrtec tablets in to minoxdil?, also does everyone get a shed on cet?

            Comment

            • KO1
              Senior Member
              • Jan 2012
              • 805

              I don't think CET is a PGD2 blocker.

              Comment

              • KO1
                Senior Member
                • Jan 2012
                • 805

                What has been disappointing to me is the lack of good results reported by Ramatroban users. As you know, it is a CRTH2 antagonist, so it should be better than Indo/Cromo...but people are reporting "stops shedding" on Indo but nothing on Rambo...

                Comment

                • Pentarou
                  Senior Member
                  • Apr 2013
                  • 482

                  The lack of success with CRTH2 blockers has been a real downer, IMO. There must be a huge vital piece in the puzzle missing. Or Cotsatelis was trolling us.

                  Comment

                  • walrus
                    Senior Member
                    • Feb 2012
                    • 298

                    Originally posted by KO1
                    I don't think CET is a PGD2 blocker.
                    A new H1 antihistamine, cetirizine, was studied to determine its effects on mediators and cellular infiltration during the cutaneous late-phase response (LPR). Ten ragweed-allergic subjects, who had previously demonstrated a cutaneous LPR, were examined in a double-blind, crossover study. Either cet …


                    Histamine release was not altered by cetirizine treatment, but prostaglandin D2 (PGD2) production, which peaked at 3 to 5 hours, was clearly reduced by cetirizine treatment, being lower at all time points during the reaction
                    and http://www.ncbi.nlm.nih.gov/pubmed/7741033

                    Cetirizine (0.1-10 micrograms/ml) enhanced PGE2 release by resting human monocytes

                    Comment

                    • KO1
                      Senior Member
                      • Jan 2012
                      • 805

                      ^Fascinating, I take that back then.

                      Comment

                      • thechamp
                        Senior Member
                        • Jan 2011
                        • 1763

                        How are people getting results with cet ??

                        Comment

                        • justeone
                          Member
                          • Nov 2011
                          • 54

                          is this treatment working at all?

                          Comment

                          • thechamp
                            Senior Member
                            • Jan 2011
                            • 1763

                            Apparently people have results mixing cet with minoxidil

                            Comment

                            • rdawg
                              Senior Member
                              • Jun 2012
                              • 996

                              Because CET is so cheap and seemingly so safe, I'm actually gonna hop on the bandwagon.

                              Ive been on Min for years now and just hit one year on FIN with simply maintanence, so i'm down to try out something new!

                              10mg for every 1ml right?

                              Comment

                              • KO1
                                Senior Member
                                • Jan 2012
                                • 805

                                I wish we could know which is the better pathway - inhibit production of prostaglandins with Cet, or inhibit the specific receptor with Rambo.

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