Cetirizine

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  • Conpecia
    Senior Member
    • Sep 2011
    • 904

    #76
    Guyfromuk, I don't have too much faith in it, just clarifying that this is distinct from one man's minox regrowth.

    Pate, I'm also wary of the possible necessity of a Cet minox combo. Hopefully we can benefit without minox though.

    I contacted Casperz for a general update, here's what he had to say:

    "The dramatic difference right now is I've got no shedding at all. I normally see many hairs in my sink and bathroom counter and I'm not seeing any at all which is very unusual so that is a plus. I'm also seeing more and more small black hairs. It's hard to see any growth but they've only been visible for a couple of weeks now. I think I'm going to stop watching so close and let things happen.

    Right now there are no negatives. The insomnia I experience the first few weeks seems to be gone as well as the eye dryness. My scalp looks and feels healthier than it has in a long time. Bottom line is I'm waiting like everyone else."



    I've taken a huge hit on the hairline this year and I'm starting to get desperate for something to just freeze my loss until 2015. I'll be giving this a go as soon as I get a few more confirmations that this indeed is stopping sheds. It's far too simple not to make an effort.

    Comment

    • Conpecia
      Senior Member
      • Sep 2011
      • 904

      #77
      Originally posted by thechamp
      Well I'm going to buy generic Zyrtec, is there any point crushing them in minoxidil ? Or not?
      I would just make a separate topical for Zyrtec. But do your research, check out the other forums who are on to this. We're all a bit behind but catching up.

      Comment

      • thechamp
        Senior Member
        • Jan 2011
        • 1763

        #78
        Ok nice

        We will see what happens

        Comment

        • rdawg
          Senior Member
          • Jun 2012
          • 996

          #79
          Originally posted by Pate
          I don't think anybody is getting too excited. We're way too cynical by this stage for that, we've seen the snake oil cures come and just as quickly fade into oblivion.

          But this is a readily available product that's easy to prepare and apply, with at least some anecdotal evidence that it works and a strong theoretical backing for it working (PGD2 inhibition).

          The other big thing it has going for it is, nobody is trying to sell us anything, so that takes the whole commercial aspect out of it. No dodgy photos under different lights or website testimonials trying to get us to buy the product, these guys reporting their results don't make a dime because we buy Zyrtec from a pharmacy.

          Also, the guy on minox had been on it for 12 months before starting this treatment so any growth should have stabilised (also you very rarely if ever hear of terminal hairs growing at the hairline in slick bald areas with minox).

          The one thing I am worried about (since I gave up on minox) is that there is a theory that minox works as a sort of proxy PGE stimulator like bimatoprost - and if that is true, it may be that you need both cetirizine AND minox to get growth. Suppress PGD2 and stimulate PGE.

          That would be something else for me to try, if I could be arsed - one side just cetirizine and one side minox and cet. But I really can't be bothered with twice a day application of anything these days.
          I am interested in mixing it with Minoxidil(is this possible? not sure if it's been answered) for this reason. Inhibit whats causing the loss(theoretically) and promote/stimulate the follicles to grow.

          and I dont think I've ever seen minoxidil cause growth in slick bald areas(especially after using it for 12 months already.)

          this is an interesting product and I'll be monitoring other people's progress(for safety reasons).

          anyone got the approximate cost on say a month's supply to make this stuff?

          Comment

          • Pate
            Senior Member
            • Sep 2011
            • 417

            #80
            Extremely cheap. I found 50 Zyrtec pills online for $30 Australian and I bet it's cheaper in the US and UK because the Australian dollar is ridiculously high right now. Desmond seems to think one pill per day is a good start so that's a nearly 2mth supply.

            If you just put it in distilled water you basically just need to buy a big bottle of that from a hardware store or something it will last you ages.

            You could put it in minox but remember it dissolves in water so water would be better to extract it from the pills.

            Still hoping Desmond gets back to my previous questions, it's so handy having a pharmacist around!

            Comment

            • rdawg
              Senior Member
              • Jun 2012
              • 996

              #81
              http://www.amazon[dot]com/Zyrtec-Allergy-Relief-Tablets-Count/dp/B0034KYA36

              are those what I need. 70 for 15 bucks!?

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                #82
                Originally posted by rdawg
                http://www.amazon[dot]com/Zyrtec-Allergy-Relief-Tablets-Count/dp/B0034KYA36

                are those what I need. 70 for 15 bucks!?
                If this works better than RU, I'm going to save so much cash..... lol.

                Comment

                • rdawg
                  Senior Member
                  • Jun 2012
                  • 996

                  #83
                  Originally posted by hellouser
                  If this works better than RU, I'm going to save so much cash..... lol.
                  Gets even cheaper went on another amazon page and found 30 for 1.86$.

                  honestly might pick them up just to keep them handy.

                  I have a feeling zyrtec pills might get sold out all over the place if this somehow works and they'll have no idea why haha

                  Comment

                  • hellouser
                    Senior Member
                    • May 2012
                    • 4419

                    #84
                    Originally posted by rdawg
                    Gets even cheaper went on another amazon page and found 30 for 1.86$.

                    honestly might pick them up just to keep them handy.

                    I have a feeling zyrtec pills might get sold out all over the place if this somehow works and they'll have no idea why haha
                    Wouldnt it be best to find what 'ingredient' is responsible for blocking PGD2 and finding pills that contain MORE of said 'ingredient' making it most effective?

                    Comment

                    • rdawg
                      Senior Member
                      • Jun 2012
                      • 996

                      #85
                      Originally posted by hellouser
                      Wouldnt it be best to find what 'ingredient' is responsible for blocking PGD2 and finding pills that contain MORE of said 'ingredient' making it most effective?
                      If we're going by what desmond said and a couple others wouldn't TOO much dosage be bad?

                      although referring specifically to pgd2, what other pills contain that blocking PGD2 affect? let's go to work guys.

                      Comment

                      • hellouser
                        Senior Member
                        • May 2012
                        • 4419

                        #86
                        Originally posted by rdawg
                        If we're going by what desmond said and a couple others wouldn't TOO much dosage be bad?

                        although referring specifically to pgd2, what other pills contain that blocking PGD2 affect? let's go to work guys.
                        I have a friend whos a chemist, used to work for the military in biological development and defense. Gonna see if he can give me some input on the matter.

                        Comment

                        • JJacobs152
                          Senior Member
                          • May 2011
                          • 293

                          #87
                          Originally posted by rdawg
                          If we're going by what desmond said and a couple others wouldn't TOO much dosage be bad?

                          although referring specifically to pgd2, what other pills contain that blocking PGD2 affect? let's go to work guys.

                          Aspirin would actually be your best bet (SARCASM). However, not sure how this would pan out. Hopefully, the side effects would stay topically. Other drugs that would act at the top enzyme in the chart below include all the NSAID drugs such as ibuprofen.

                          However, I wouldn't use aspirin, just because you need the other prostaglandins to function properly. Also, increased intake of aspirin or any other non steroidal antiinflammatory increases the risk for gastric ulcers.

                          Comment

                          • thechamp
                            Senior Member
                            • Jan 2011
                            • 1763

                            #88
                            Aspirin

                            Some people where talking about aspirin on an๔ther forum come guys let's get mpb out of our lives

                            Comment

                            • rdawg
                              Senior Member
                              • Jun 2012
                              • 996

                              #89
                              Originally posted by thechamp
                              Some people where talking about aspirin on an๔ther forum come guys let's get mpb out of our lives
                              The person above said why you SHOULDNT use aspirin. However other alternatives may be out there that are better PGD2 inhibitors than zyrtec. I am no scientist though, So I dont want to start using things that are harmful.

                              Comment

                              • JJacobs152
                                Senior Member
                                • May 2011
                                • 293

                                #90
                                Originally posted by thechamp
                                Some people where talking about aspirin on an๔ther forum come guys let's get mpb out of our lives
                                You're best bet is going with a selective Cox-2 inhibitor. This will reduce the amount of PGD2 without having the harsh systemic effects of completely blocking out prostaglandin synthesis (ie vasoconstriction, renal failure, acute gastritis, etc etc). The drug on the market that is a selective cox-2 inhibitor is ka Celecoxib.

                                Paging Desmond & unk to share more insight on the pharm behind this. Honestly, if you can reduce PGD2 levels in the scalp, without affecting the levels elsewhere in the body - you'll be set.

                                Comment

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