Is this the secret PGD2 Inhibitor that Cotsarelis was referring to?

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • Westonci
    Senior Member
    • Feb 2010
    • 251

    Is this the secret PGD2 Inhibitor that Cotsarelis was referring to?

    Heres the companies website, with their upcoming drugs in clinical trials.

    The drug is called "OC000459"

  • TravisB
    Senior Member
    • May 2012
    • 188

    #2
    It's being developed for asthma and in oral form. They don't plan making topical for hairloss, and I doubt taking it orally would be safe or effective against hairloss.

    It's probably 2-3 years away

    Comment

    • Desmond84
      Senior Member
      • Oct 2012
      • 987

      #3
      Originally posted by Westonci
      Heres the companies website, with their upcoming drugs in clinical trials.

      The drug is called "OC000459"

      http://www.oxagen.co.uk/index.htm
      Holy sh##! It is TOO

      According to clinicaltrials.gov all their Phase 2 studies have now completed! Here's the link:



      Assuming they start Phase 3 by March 2013, we should have this product FDA-approved by September 2014!

      The future's looking very bright and looks like Costraelis was right about it being available in the next 2 years!!!

      P.S. Its actually great how it is in oral form NOT an inhaler. Hopefully if it has the right physiocochemical properties we can find a way to make it into a topical preparation

      Comment

      • Desmond84
        Senior Member
        • Oct 2012
        • 987

        #4
        Here's some interesting facts about Oxagen's OC000459:

        1) Phase 2b is finished and the results are published. Here's a small outline of what they found in their latest trial (Phase 2b):



        2) This is where they stand at the moment:

        "The company is in the process of moving its OC000459 programme forward to position it for Phase III pivotal trials"

        Very happy right now

        Comment

        • Desmond84
          Senior Member
          • Oct 2012
          • 987

          #5
          Bahahahhahaha

          These guys are already selling it! What the hell....



          Man I'd rather wait 18 months and make sure its safe than to risk my health on a completely experimental treatment that may not even work!

          Comment

          • bananana
            Inactive
            • Feb 2012
            • 524

            #6
            holy...
            damn, someone should buy it and try it

            I suppose it cant do any damage, but the price is whoooah. More than $300 for 1 gram. What should one dilute it down to? 1% mix?

            But we're just guessing now. I hope it will be even more successful than cetirizine.

            Comment

            • Dazza
              Senior Member
              • Jun 2012
              • 264

              #7
              The folks over at HLH have been using this for awhile now, so far the results are roughly the same as the people trying cet. They are having trouble making a vehicle with the OC as its not dissolving fully.

              Comment

              • rdawg
                Senior Member
                • Jun 2012
                • 996

                #8
                Those trials are for asthma though right? Wouldnt it be done differently for baldness?

                Comment

                • Cob984
                  Senior Member
                  • Sep 2012
                  • 526

                  #9
                  who if anyone is on the inhibitor over at m p b treatments.com, its currently sold out but wonder if anyone is using that on any forum?

                  Comment

                  • neversaynever
                    Senior Member
                    • Dec 2011
                    • 640

                    #10
                    Is old news, and a number of people are already trying but noone knows what the correct vehicle and dose are.

                    Comment

                    • bigentries
                      Senior Member
                      • Dec 2011
                      • 465

                      #11
                      Yes no need to get depressed because a bunch of amateurs (with a dubious source) are not getting results

                      Just need to take in consideration that these things take time, it will be a while until we get any news at all

                      Comment

                      • rdawg
                        Senior Member
                        • Jun 2012
                        • 996

                        #12
                        Originally posted by bigentries
                        Yes no need to get depressed because a bunch of amateurs (with a dubious source) are not getting results

                        Just need to take in consideration that these things take time, it will be a while until we get any news at all
                        Pretty much this. We can all try our hand in the grey market stuff, but for all we know it works perfectly well and we're just injected it/using it completely wrong.

                        PGD2 hasn't been proven wrong or right, but it's a 3rd generation product IMO, meaning it's years away if it is worth using(2nd generation is Aderans, Bim and Histogen.)

                        Bim or Aderans is next guys, followed by Histogen soon after. 2 years away it seems!

                        Comment

                        • john2399
                          Senior Member
                          • Jan 2012
                          • 521

                          #13
                          Could this be the end for propecia ? I hope pdg2 works!

                          Comment

                          • bigentries
                            Senior Member
                            • Dec 2011
                            • 465

                            #14
                            Originally posted by rdawg
                            Pretty much this. We can all try our hand in the grey market stuff, but for all we know it works perfectly well and we're just injected it/using it completely wrong.

                            PGD2 hasn't been proven wrong or right, but it's a 3rd generation product IMO, meaning it's years away if it is worth using(2nd generation is Aderans, Bim and Histogen.)

                            Bim or Aderans is next guys, followed by Histogen soon after. 2 years away it seems!
                            To be fair, if said bunch of amateurs got results from a dubious source, it would be great since we would be assured it works in some way

                            Right now we are still in a limbo

                            Comment

                            • BaldinLikeBaldwin
                              Senior Member
                              • Apr 2012
                              • 223

                              #15
                              there's a lot of complaining and whining going on BTT. "when do we get new treatments?" "why do we only have devil drug poison propecia?" and so on..

                              all very well but there are people at the forefront of experimental treatments
                              contributing to the common cause and trying to find better treatments. to bash these people while at the same time doing nothing oneself to move the movement forward looks very bad in my eyes..

                              as things stand prostaglandins are only a part of the puzzle and targeting them might not be enough since it's further down the MPB pathway in comparison to anti androgen treatment which hits it at the bottleneck

                              Comment

                              Working...