Tsuji-lab (Team Tokyo)

[UK_]

I can shed some light:

Nothing has happened and we are still 10 years away.

[bananana]

I can shed some light:

Nothing has happened and we are still 10 years away.

Dont be a pessimist. We know nothing yet.

[clandestine]

I can shed some light:

Nothing has happened and we are still 10 years away.

C'mon, UK_, that attitude isn't going to get us anywhere. Try exuding some optimism! A lot of good things are happening, and very fast. Try to see that.

[StayThick]

C'mon, UK_, that attitude isn't going to get us anywhere. Try exuding some optimism! A lot of good things are happening, and very fast. Try to see that.

I like to be as optimistic as the next guy...I'm with UK here. Progress might be made, but progress for MPB is moving at a snails pace.

I don't care about treatments 10 years away. What's happening in the foreseeable future?? I want updates on treatments making serious progress for the now not the maybe 10 years out progress. I'm tired of it. I'm tired of balding NOW!

[UK_]

C'mon, UK_, that attitude isn't going to get us anywhere. Try exuding some optimism! A lot of good things are happening, and very fast. Try to see that.

I honestly cant see it - every damn year it's the same story: we're 5 years away... we're 5 years away... every other field seems to be steaming ahead and throwing out remarkable new treatments while we're still stuck in 1985 (minox & fin).

[ccmethinning]

I honestly cant see it - every damn year it's the same story: we're 5 years away... we're 5 years away... every other field seems to be steaming ahead and throwing out remarkable new treatments while we're still stuck in 1985 (minox & fin).

It seems all the researchers in the hair loss industry are either snake oil salesmen or all the people who weren't smart enough to research an "important" disease.

[PatientlyWaiting]

I think it has more to do with the funding, on why the hair loss field doesn't have a cure or at least some thing better than minoxidil, finasteride, and dutasteride.

The government will never help fund something like Male Pattern Balndess. That is why it's taking so long, and every 5 years there's another 5-10 years 'til the cure. It's as if they are giving us the run around.

The best I can do is just take my finasteride/dutasteride pills and put on my Rogaine, and cover myself up with Toppik. Maybe i'll get some thickening and regrowth, enough to move on for a little while.

[Desmond84]

Hey guys, just a thought:

"Tsuji lab created a hair germ and implanted it into the kidney of a mouse (subrenal capsule)...allowed it to mature. Took out the newly formed hair follicles and transplanted it on the back of the mouse using the FUT technique!"

Now, that is all good and well...but how are they going to grow the hair germs in a human study? They obviously can't implant it into our kidney cavities! Right?

So, that's where something really interesting came to my mind!

This is where Dr. Lauster's microchip technique comes in! Each chip contains six identical dynamic micro-bioreactors with three different micro-organoid culture segments (A liver, a brain cortex and a bone marrow micro-organoid segment) providing a feed supply and waste reservoirs.

With these chips, they might be able to grow them to full maturity!

I personally think Tsuji & Lauster are complementary scientific techniques, BOTH feeding off each other!

What do u guys reckon?

[Boldy]

Hey guys, just a thought:


I personally think Tsuji & Lauster are complementary scientific techniques, BOTH feeding off each other!

What do u guys reckon?

Indeed it is.

[young]

I don't see how funding would be a problem.

Those who bring out the cure will have an absolute tsunami of money coming in.

[Tomb10]

so if this is ever gonna be reality, it is possible to place, for example. 60000 grafts. and there's not longer a need to take meds

[Thinning87]

Hey guys, just a thought:

"Tsuji lab created a hair germ and implanted it into the kidney of a mouse (subrenal capsule)...allowed it to mature. Took out the newly formed hair follicles and transplanted it on the back of the mouse using the FUT technique!"

Now, that is all good and well...but how are they going to grow the hair germs in a human study? They obviously can't implant it into our kidney cavities! Right?

So, that's where something really interesting came to my mind!

This is where Dr. Lauster's microchip technique comes in! Each chip contains six identical dynamic micro-bioreactors with three different micro-organoid culture segments (A liver, a brain cortex and a bone marrow micro-organoid segment) providing a feed supply and waste reservoirs.

With these chips, they might be able to grow them to full maturity!

I personally think Tsuji & Lauster are complementary scientific techniques, BOTH feeding off each other!

What do u guys reckon?

definitely good stuff, there's nothing to say besides hoping that research comes along this path. But for right now, we're better off working hard and living our lives.

[Desmond84]

Japan OKs world’s first iPS stem cell clinical trial

OK guys, so finally scientists are becoming brave enough to test out induced pluripotent stem cells (iPS) on humans!

The first ever human trial using iPStem cells will be conducted on "semi-blind" patients suffering from Macular degenration. The place of trials is set in Japan and the first patient should get his/her first injection by June 2014!

Six patients have been selected for this trial and the study will go on for 4 years to see if any of the stem cells will turn cancerous!

__________________________________________________ _______________

So, how does this affect us and why is this in the Tsuji lab thread?

Well, for starters Tsuji lab will need to multiply your stem cells to make "hair germs". The easiest way to produce stem cells atm is by converting skin cells into stem cells! These newly formed stem cells are termed "induced pluripotent stem cells" and have all the characteristics of a stem cell!

So what's stopping us from using it till now?

We've known for sometime that cancer cells go through a very similar process known as 'undifferentiation' which is pretty much a normal cell (e.g. skin cell) turns into a stem cell-like body and then into a cancerous cell (e.g. melanoma).

Since we use a very similar method to produce a stem cell (iPS), we have no idea how safe they are or whether they have the potential to turn cancerous.

If this trial shows high level of safety, you can be more than certain that many trials will follow including those promised by Tsuji lab!

[StinkySmurf]

OK guys, so finally scientists are becoming brave enough to test out induced pluripotent stem cells (iPS) on humans!

The first ever human trial using iPStem cells will be conducted on "semi-blind" patients suffering from Macular degenration. The place of trials is set in Japan and the first patient should get his/her first injection by June 2014!

Six patients have been selected for this trial and the study will go on for 4 years to see if any of the stem cells will turn cancerous!

Hola Desmond!

iPS seems to be the big hope for Parkinson's research too. I just read the other day they were trying to get an iPS trial going for that as well.

Scientists to test iPS cells for Parkinson's disease therapy

[KO1]

Desmond, I agree that iPS is fascinating stuff, but let's tamp down expectations, it's a long way away, and given the serious safety concerns (cancer), it's unlikely to be used for a cosmetic condition so early.