Replicel Trial Update

[Bronson]

Now go outside, smell a rose, drink a cold beer and try to think of something else until March...

That's the smartest thing I've read on this forum yet

[PatientlyWaiting]

So Replicel is an injection?

If it is, that's what I like to hear. I'm tired of all of these surgeries.

[CVAZBAR]

According to the blogpost from Biotuesdays.com it was 10% to match Rogaine and 10-15% to match Propecia but that might have been the site mentioned screwing around with the numbers. I wish people would have read my post and realized the point was that the 20% number was not a prediction but a goal for the clinical trial and that nobody should hang their heads because of it. David Hall also said he believes this could be the cure for male pattern baldness; +20% is not the holy grail they're looking for, it is simply what they would consider a great result from the first phase of their clinical trials.

By the way, for those who don't know, this is not the trial phase where you attempt to optimize efficacy. It's the trial phase where you're really just trying to provide numbers that proves your concept and its safety. Even if it's 20%
by the first trial phase it could be 50% by the time it hits the market.

Now go outside, smell a rose, drink a cold beer and try to think of something else until March...

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

[uninformed]

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

In a sense yes, because they are injecting a dose many times larger than what they estimate to be an appropriate dose in phase 1 to test for safety.

However, they are not trying different mediums, different ways of injections and what not.

I think at the very least they will try and see if there's compoundable benefits in phase 2. Don't worry mate as Spencer said they are giving a very modest estimate because they don't want to oversell their product. Like many others here I have great confidence in them.

Bring on March!

[Jundam]

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.

[uninformed]

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.

They are partnered with a well known hospital in southern china, my nephew was born there earlier this year actually.

[CVAZBAR]

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.

I see what you're saying. That's a good point!

[headlikeafuckingorange]

Interesting. Does anyone know a ball park figure of how much this would cost? Is it a regular treatment like propecia or more of a one-off like a HT.

Just wanting to know whether I should start saving now...

[eqvist]

Interesting. Does anyone know a ball park figure of how much this would cost? Is it a regular treatment like propecia or more of a one-off like a HT.

Just wanting to know whether I should start saving now...

Saving isnīt bad however =)


Is it a crime to talk about the results if you are in a trail?

[uninformed]

Saving isnīt bad however =)


Is it a crime to talk about the results if you are in a trail?

yeh cos you have to sign a nondisclosure contract. the trial is supposed to be double blind,which i assume event replicel don,t know exact results till review day. Furthermore the area is probs so small its hard to see at first without camera

[Morgan137]

Eh, 2015 i think is quitely far for me. So, as one man told before "patience, patience, patience".