Aderans - clinical trials

[Sogeking]

You got something mixed up. I think Replicel got 50% density of hair regrowth in all of mice. Meaning 100% succes of 50% regrowth in mice.
Which, if by some wonder translates to humans would be unbelivable and would probably solve all of our problems. However we will see about that.

[Reece]

Have we ever been this "close" before? I am fairly new to the hair loss community (26 NW 2.5 and moving fast). I don't know if this is the kind of hype that propecia brought about or if it was always advertised as "10% growth". Some of these companies have been working on these formulas for over a decade, I just don't know if they ever hyped trial results as they are now.

I am trying to be careful to not get too excited and anticipate the best case scenarios. It seems that if these results only show very minimal progress than we may be back to the drawing board and another waiting game. Trying to stay optimistic though.

[uninformed]

Have we ever been this "close" before? I am fairly new to the hair loss community (26 NW 2.5 and moving fast). I don't know if this is the kind of hype that propecia brought about or if it was always advertised as "10% growth". Some of these companies have been working on these formulas for over a decade, I just don't know if they ever hyped trial results as they are now.

I am trying to be careful to not get too excited and anticipate the best case scenarios. It seems that if these results only show very minimal progress than we may be back to the drawing board and another waiting game. Trying to stay optimistic though.

not sure how you can hype trial results when companies are either waiting on results or show exiating data. results are pics and numbers for everyone to see you cant 'hype' them

[RichardDawkins]

Uninformed your nick speaks volumes, Just shut it there comes nothing of value from guys like you except bickering nd crying

[uninformed]

Uninformed your nick speaks volumes, Just shut it there comes nothing of value from guys like you except bickering nd crying

Just when I thought you are starting to recover from your fall from grace, the dorkins within is back.

I am just saying companies can't afford to create expectations they can't meet and I am apparently bickering and crying trololololol. Maybe you should clean up your own acts before you speak.

[Reece]

Didnt mean to stir up any bickering and I suppose i should of clarified that the hype for "potential" results is primarily from the hair loss community.

My question was more have ever been this "seemingly" close? I realize that there is no official human evidence yet but I am wrong to be a bit excited about the potential?

[RichardDawkins]

Well thats debatable but to be honest i think that they already tested a lot of stuff on human.

In one interview with SK there was one Replicel guy who had one minor thing slipped over his tongue

"The results on humans... ahhh mice were good so far"

Its like this 9/11 thing " Well yeah when a missile hits the Pentagon i mean an airplane"

[Jundam]

It would definitely not surprise me if they tried it on humans before they began clinical trials. After all, if they can determine if it works or not off the records they either know it's not going to work and can scrap the project and save a lot of time and money, or they know it's got a lot of potential and can move forward with confidence.

[uninformed]

Didnt mean to stir up any bickering and I suppose i should of clarified that the hype for "potential" results is primarily from the hair loss community.

My question was more have ever been this "seemingly" close? I realize that there is no official human evidence yet but I am wrong to be a bit excited about the potential?

yeh sorry if it sounded like i was being harsh. We are all in the same boat here and I think we all hope for the best. They are probably pretty sure in terms of whether it works on humans, since ARI threw more than 100 million dollars into it =P

[Losing_It]

Didnt mean to stir up any bickering and I suppose i should of clarified that the hype for "potential" results is primarily from the hair loss community.

My question was more have ever been this "seemingly" close? I realize that there is no official human evidence yet but I am wrong to be a bit excited about the potential?

No worries, Dawkins tend to go wild some time. There are some real stuff coming down pipeline. Lets just say if Spencer is confident then I am also confident

[RichardDawkins]

Btw didnt spencer promise to give us an IHRS update? :-)

[UK Boy]

Aderans Info

I know this is a couple of weeks old but I didn't see anyone post it on here so thought it might be of some interest.

Atlanta, GA (PRWEB) October 20, 2011

Aderans Research reached a major milestone in its hair restoration studies recently when the company enrolled its 300th subject in Phase 2 of its clinical trial. With a goal of at least 350 subjects, Aderans is well on its way to expanding industry knowledge about cell-based engineering solutions for pattern hair loss.

“We will continue to evaluate various combinations of the Ji Gami™ cell family in clinical treatment regimens,” said Chief Executive Officer Ken Washenik, M.D., Ph.D.

“The results are very encouraging thus far, and we’re on course to finish Phase 2 next year,” added Vern Liebmann, Chief Operating Officer.

Launched in November 2008, Phase 2 is being conducted across the United States and is open to select individuals who suffer from androgenetic alopecia. Aderans continues to recruit subjects; visit http://www.aderansresearch.com/ari_clinicupdates.html for current locations.

In another landmark, Aderans recently patented (U.S. # 7,985,537) and trademarked its proprietary laboratory test, Aderans HPA™, developed to discern and assess cell formulations in terms of their hair-forming ability. “This unique test can effectively detect cells that produce hair follicles,” said Kurt Stenn, MD, Vice President and Chief Scientific Officer. “It is a standard in the industry.”

It is ARI’s hope that its state-of-the-art cell engineering solutions will both positively impact those in the study and set an example for the industry as a whole.

Good to know that they appear to be progressing and that they state they are on track to finish phase II next year. It's also interesting to read about their lab test for assessing the hair forming ability of different formulations - sounds like a useful tool for the hair restoration community to have access to.

[melwou7245]

I know this is a couple of weeks old but I didn't see anyone post it on here so thought it might be of some interest.

Atlanta, GA (PRWEB) October 20, 2011

Aderans Research reached a major milestone in its hair restoration studies recently when the company enrolled its 300th subject in Phase 2 of its clinical trial. With a goal of at least 350 subjects, Aderans is well on its way to expanding industry knowledge about cell-based engineering solutions for pattern hair loss.

“We will continue to evaluate various combinations of the Ji Gami™ cell family in clinical treatment regimens,” said Chief Executive Officer Ken Washenik, M.D., Ph.D.

“The results are very encouraging thus far, and we’re on course to finish Phase 2 next year,” added Vern Liebmann, Chief Operating Officer.

Launched in November 2008, Phase 2 is being conducted across the United States and is open to select individuals who suffer from androgenetic alopecia. Aderans continues to recruit subjects; visit http://www.aderansresearch.com/ari_clinicupdates.html for current locations.

In another landmark, Aderans recently patented (U.S. # 7,985,537) and trademarked its proprietary laboratory test, Aderans HPA™, developed to discern and assess cell formulations in terms of their hair-forming ability. “This unique test can effectively detect cells that produce hair follicles,” said Kurt Stenn, MD, Vice President and Chief Scientific Officer. “It is a standard in the industry.”

It is ARI’s hope that its state-of-the-art cell engineering solutions will both positively impact those in the study and set an example for the industry as a whole.

Good to know that they appear to be progressing and that they state they are on track to finish phase II next year. It's also interesting to read about their lab test for assessing the hair forming ability of different formulations - sounds like a useful tool for the hair restoration community to have access to.

Just to confirm, this is the treatment where they take your own stem cells out of your own bone marrow, do a tequila mix, inject it back and your old dead hair follicles pull a zombie move and become active again?

So it's in phase II - how many phases are there going to be? Also any idea on the possible cost?

Also, even if they revive old dead hair follicles, won't the DHT just kill them again?

[Kampung101]

Just to confirm, this is the treatment where they take your own stem cells out of your own bone marrow, do a tequila mix, inject it back and your old dead hair follicles pull a zombie move and become active again?

So it's in phase II - how many phases are there going to be? Also any idea on the possible cost?

Also, even if they revive old dead hair follicles, won't the DHT just kill them again?

I'm not sure about the bone marrow, but they do something very similar to Replicel in that they take a small biopsy from the back of the head where the hair cells are resistant to DHT. The difference is that Aderans is taking the DP cells, whereas Replicel is taking the Dermal Cup cells.

And the revived old hair follicles should be permanent as the newly implanted DHT resistant cells are migrating to those follicles.

Thats at least my understanding of this.

[melwou7245]

I'm not sure about the bone marrow, but they do something very similar to Replicel in that they take a small biopsy from the back of the head where the hair cells are resistant to DHT. The difference is that Aderans is taking the DP cells, whereas Replicel is taking the Dermal Cup cells.

And the revived old hair follicles should be permanent as the newly implanted DHT resistant cells are migrating to those follicles.

Thats at least my understanding of this.

OK, that's pretty concise, thanks. My second question - these Dermal Cup cells and DP cells, where do they get them? From your body, or cooked up in a lab?