Nitric Oxide Gel for Promoting Hair Growth

[Thinning@30]

According to wikipedia, minoxidil contains nitric oxide, and this is conjectured to part of its mechanism of action.

Since these are official clinical trials, I'm not going to denounce this off the bat as a scam. If it were an outright scam, the people selling this wouldn't bother with clinical trials, but would sell it to us anyway with no photographs, hair counts, or other measures of efficacy, but would claim it was some miracle treatment that was being suppresed by big pharma.

What I want to know is what would be the delivery mechanism, i.e. oral, topical, scalp injection, etc., and what is the expected efficacy?

Must be good living in the mouse world. There are probably no mice with MPB since every hair loss treatment works on them, even TRX2

I understand the frustration, but for the record, mice don't ever get MPB. Pattern baldness is limited to humans and a handful of other primates. This is why so many mouse cures don't work for us. The mechanisms behind human and mouse hair loss are different. The researchers really ought to skip mice trials and test their stuff on stump-tailed macaques.

[PatientlyWaiting]

According to wikipedia, minoxidil contains nitric oxide, and this is conjectured to part of its mechanism of action.

Since these are official clinical trials, I'm not going to denounce this off the bat as a scam. If it were an outright scam, the people selling this wouldn't bother with clinical trials, but would sell it to us anyway with no photographs, hair counts, or other measures of efficacy, but would claim it was some miracle treatment that was being suppresed by big pharma.

What I want to know is what would be the delivery mechanism, i.e. oral, topical, scalp injection, etc., and what is the expected efficacy?



I understand the frustration, but for the record, mice don't ever get MPB. Pattern baldness is limited to humans and a handful of other primates. This is why so many mouse cures don't work for us. The mechanisms behind human and mouse hair loss are different. The researchers really ought to skip mice trials and test their stuff on stump-tailed macaques.

Mice get MPB. It's called Mice Pattern Baldness.

[UK_]

Minox might contain elements of nitric oxide but this article is CLAIMING their compound grew new hair follicles - now either there is something we are missing regarding their formula or this trial was a load of bullshit.

[RichardDawkins]

I am open for everything if it has nothing to do with stop spanking the monkey :-)

[doke]

According to wikipedia, minoxidil contains nitric oxide, and this is conjectured to part of its mechanism of action.

Since these are official clinical trials, I'm not going to denounce this off the bat as a scam. If it were an outright scam, the people selling this wouldn't bother with clinical trials, but would sell it to us anyway with no photographs, hair counts, or other measures of efficacy, but would claim it was some miracle treatment that was being suppresed by big pharma.

What I want to know is what would be the delivery mechanism, i.e. oral, topical, scalp injection, etc., and what is the expected efficacy?



I understand the frustration, but for the record, mice don't ever get MPB. Pattern baldness is limited to humans and a handful of other primates. This is why so many mouse cures don't work for us. The mechanisms behind human and mouse hair loss are different. The researchers really ought to skip mice trials and test their stuff on stump-tailed macaques.

Hi the stump tail macaques and others in the monkey family suffer mpb,so thats what they should be testing on.
I think the Latisse topical was on stump tailed monkeys and it did regrow there hair?

[UK_]

I am open for everything if it has nothing to do with stop spanking the monkey :-)

Ahhhhh!!! That's it!!! The mice were not masturbating thats why it worked so well!!!

[doke]

there was a mouse where? there on the stairs there on the stairs right now,a little mouse with clogs on well i declare going cccclop on the stairs with a full head of hair hahaha

[RichardDawkins]

Uk you solved the puzzle. Stop the presses and stop research.

Uk please can you start a thread a new one with those incredible findings? Thanks in advance

[Mr. 4000]

Minox might contain elements of nitric oxide but this article is CLAIMING their compound grew new hair follicles - now either there is something we are missing regarding their formula or this trial was a load of bullshit.

place your bets!

[RichardDawkins]

I call it benefit of doubt with shift towards bullshit

[UK_]

I just hope they come out with some sort of explanation of how the hell they were able to grow new follicles - I mean we here all know what a daunting task that would be....

...I'd be relieved if they said their compound had some sort of mixture with other growth factors etc that targeted the wnt pathway... if that's the case then this gel may have applications for grey hair aswel.

[Thinning@30]

If the product is in phase 2 human trials, then there must have a phase 1 human trial that demonstrated some level of safety and efficacy. I understand everyone's cynicism, since we've been down this road so many times before, but AFAIK Nitric Oxide isn't being marketed specifically as a hair loss treatment. I see room for cautious optimism here. The fact that there is a clinical trial puts this one ahead of TRX2, Bioregenerative Sciences, and all the other crap treatments that are out there.

I am very curious about the follicle genesis part, since we know minoxidil doesn't do that.

[UK_]

I guess we will just have to wait until April - I am still shocked that they managed to use something as widely used as NOS to grow new hair follicles in mice and rats.

April is 10 months away, I guess time will fly between now and then.

[VictimOfDHT]

10 months away ? That can also mean a lot of hair lost. God damn, why is it always in the future when it comes to hair loss treatments?

[KeepTheHair]

10 months mean nothing dude. It will probably take much longer and maybe not work at all...most likely not work at all.


meh