Replicel

[yeahyeahyeah]

So it's basically like Minoxidil, Finasteride? How effective is it compared to aforementioned treatments? Just another thing we can add to the arsenal? Now it will be the big 4 instead of big 3 or what?

Yes, WITHOUT the sides!

[oracle]

We need to see the data stratified by sex before getting down on the numbers. 9 of the 19 subjects were female. It seems to me that this treatment would more effective in men due to the quality cells in the male donor area. I don't think women have this stable donor area to pull cells from which, which could compromise their results.

[Thinning@30]

At first glance, these results while positive, don't seem that impressive. I wonder if this will be like Histogen though, where greater efficacy was seen at the one year mark. Will the phase I subjects continue to be monitored? Also, it is not clear yet if the treatment is compoundable or if the injections could "immunize" follicles against further loss.

Also, remember that the Replicel injections were to the subjects' temples, which are considered much more difficult to treat than the crown. It could be more effective in other parts of the scalp, we just don't know yet. Maybe in the future we'll get stem cell treatments and a conventional FUE transplant for the hairline.

Like so many of you, I was hoping Replicel would demonstrate greater than 20.0% increase in terminal hairs, and we'd be seeing pictures of thick patches of hair where before there was only slick bald skin, but I still think there is room for some cautious optimism. I'm looking forward to Replicel's interview with Spencer.

Also, completely off-topic, the Project Norma researchers were supposed to put out a newsletter last week regarding the status of their Astressin-b trial, has anyone heard from them?

[uninformed]

It worries me that 37% of the placebo group showed an increase in hair density. That shows me that those who were measuring the results wanted to see an increase. Even in a double blind situation they wanted positive results.
If someone understands this differently from me I'd be keen to hear your interpretation.

How can you be biased when all you are doing is counting hair?

[NotDyingBald]

I know how much we want to hear 500% regrowth guys.

But we need to interpretate the numbers released. We are not talking about regrowth after the use of Minox, Fin, or whatever, where the follicles producing hair are already there, hair strucutures are already formed. Don´t forget that this is introduncing new cells into the scalp, so it takes time for the body to establish them, evolve and finally start working(producing hair)

So, if from Minox we need at least 6 months to start seeing(if they are) results, and 1 year or more, from Fin, i think that having hair growth from new structures only 6 months after injection(and in phase 1), its definitely good news.

Oh, and with that little tiny detail: without having to take the chances of having your dick dead.

[oracle]

How can you be biased when all you are doing is counting hair?

Since females were also present in the placebo group, I'm not overly concerned that some placebo subjects showed improvement. These high level results aren't very meaningful when male and female are grouped together since hairloss in males and females acts differently.

[uninformed]

Since females were also present in the placebo group, I'm not overly concerned that some placebo subjects showed improvement. These high level results aren't very meaningful when male and female are grouped together since hairloss in males and females acts differently.

Yeh i am not concerned at all. It's just that some people here thinks that you can some how "make" the results more positive and that the improvements in the placebo group is an indication of the researcher's desire for positive results

[NeedHairASAP]

what kind of placebo did they use?


I dont get how the placebo was better than the actual thing?

[NeedHairASAP]

So it's basically like Minoxidil, Finasteride? How effective is it compared to aforementioned treatments? Just another thing we can add to the arsenal? Now it will be the big 4 instead of big 3 or what?

it's like minox, but not as effective


which is..... laughable


So...

1. dont give a release date for results
2. give vague date, and miss it
3. dont get the results of 16 patients out in time for annual report
4. hire stock pumper then realease sketchy stock disclaimer
5. finally release shitty results

conclusion: a complete success

[uninformed]

it's like minox, but not as effective


which is..... laughable


So...

1. dont give a release date for results
2. give vague date, and miss it
3. dont get the results of 16 patients out in time for annual report
4. higher stock pumper then realease sketchy stock disclaimer
5. finally release shitty results

conclusion: a complete success?

Tell me what would they've gained from stock pump?

[NeedHairASAP]

Tell me what would they've gained from stock pump?

a phase 2


and who knows what else. ask the SEC


if there was nothing to gain why'd they hire PR? and a stock pumper PR guy at that...

[The Alchemist]

The placebo groups recieved injections. The wounding process incurred from the injection may be responsible for some the results seen in the placebo group.

[uninformed]

a phase 2


and who knows what else. ask the SEC


if there was nothing to gain why'd they hire PR? and a stock pumper PR guy at that...

YEP cos they needed the pump for more cash for phase 2.....

Oh wait, they don't gain additional equity from the secondary market AND they've already secured their funding for phase 2 through private investors BEFORE the "pump".

Please stop talking if you don't have anything useful to contribute.

[clandestine]

All in all I find these results rather disappointing. Just my impression, though.

[kaandereli]

12% increase in vellus hair.seemingly bad but hope it will compund in 12 and 24 months follow ups.