Replicel

[Artista]

The basic point is " to confirm treatment" meaning its EFFICACY.
You cannot snap photos to post to the public midway through a full blown medical STUDY.

[stilted]

dude i can almost see this stock crashing, would love to profit from this, but dont know how!

It's called buying a put option on REPCF, although I doubt you can find a place to do it on a penny stock.

[UK_]

http://www.cnsx.ca/Page.asp?PageID=2013&AA_RecordID=462

Heres the company on the Canadian Stock Exchange.

[UK_]

Forgot to add:

http://www.investmentpitch.com/video/0_7p0c1ed8/Replicel-CNSX-RP-Video-News-Alert

[Dan26]

Thanks for the info. I didn't see the Rodman and Renshaw presentation.

They definitely did list their original timepoints as 6, 12 and 24. They've obviously changed it - which seems bizarre. Maybe they want to focus all their efforts on the Phase IIb. But it's a big loss IMO.



Not quite. 5AR inhibitors inhibit the production of DHT. But they aren't really anti-androgens in the true sense of the word, they anti-5AR drugs. True anti-androgens do stop androgens binding to the androgen receptor in the hair follicle, usually by competing antagonistically (ie blocking the receptor without activating it). A true anti-androgen will work on both T and DHT.

Unfortunately, stopping it binding to the hair follicle doesn't cure it like you suggested. It will stop hair loss progressing if you use it early enough, but regrowth will be limited, and we now think that is because the PGD2 remains even after the androgens are blocked.

Yea man that's what I was saying. My point was that fin is not necessary to regrow hair. You need anti androgen to stop, growth factor to repair, and PGD2 to create an environment in which you will actually grow hair.

[UK_]

Yea man that's what I was saying. My point was that fin is not necessary to regrow hair. You need anti androgen to stop, growth factor to repair, and PGD2 to create an environment in which you will actually grow hair.

I dont even think we need to go through all those stages, the answer to hair loss is stuck on the back of all our heads. All we need to do is create a therapy like replicels in which we can replicate the immune hairs on the back of the head, combine it with a HT and there you have it.... NW7 to NW1.

[Conpecia]

I dont even think we need to go through all those stages, the answer to hair loss is stuck on the back of all our heads. All we need to do is create a therapy like replicels in which we can replicate the immune hairs on the back of the head, combine it with a HT and there you have it.... NW7 to NW1.

Not sure if you know the answer to this, but do donor area hairs behave the same way as the original hairs? I seem to remember something about how they fall differently and feel different, also distinctly remember Scissorboy saying that in his video on Gho. That's my biggest hesitation when it comes to HTs.

[UK_]

Not sure if you know the answer to this, but do donor area hairs behave the same way as the original hairs? I seem to remember something about how they fall differently and feel different, also distinctly remember Scissorboy saying that in his video on Gho. That's my biggest hesitation when it comes to HTs.

The difference is slight - and in all honesty - id choose a full head of donor hair over baldness any day of the week. From looking at how people are able to style their hair after a HT, the only issues preventing them from looking completely natural IMHO are either awful jobs on the side of the surgeon or simply rubbish coverage (eg poor survival rate of grafts).

I just wish we could get to a stage where we could get a HT done, say 3000 grafts, then go in a week later for injections until we're happy with the density/coverage. For decades surgeons and patients have understood the prime problem with treating hair loss is limited donor, the 'type' of hair hasnt been a major factor preventing them from proceeding to address this central issue.

Then again, we'd all love to walk into a chemist, get a tub of "NeverBald" and wake up as a NW1. I just prefer to take interest in what seems more realistically plausible.

[Dan26]

I was actually going to add what you just said at the end of my comment. I rather just get a full coverage HT then have to deal with a bunch of different topical s or injections. It would be annoying and constantly draining your pockets. With cloning of donor hair a full coverage HT should not be THAT expensive, compared to extracting thousands of grafts.

[UK_]

Yeh exactly - & its much easier to get through trials compared to a new drug that needs over 150 million in investments & a ten year study.

[hellouser]

Just got an email from the Replicel newsletter:

Phase II Dose Ranging Trial on its Hair Cell Replication Technology Expected to Commence Mid-2013 VANCOUVER, BC – November 7, 2012 – RepliCel Life Sciences Inc. (the “Company” or “RepliCel”) (OTCBB: REPCF) is pleased to report on its pre-filing scientific meeting with the German Competent Authority responsible for cellular therapies – the Paul Ehrlich Institute [...]

That seems like a long time between end of Phase I and beginning of Phase II. They should have started by now.

[hellouser]

Just got an email from the Replicel newsletter:

Phase II Dose Ranging Trial on its Hair Cell Replication Technology Expected to Commence Mid-2013 VANCOUVER, BC – November 7, 2012 – RepliCel Life Sciences Inc. (the “Company” or “RepliCel”) (OTCBB: REPCF) is pleased to report on its pre-filing scientific meeting with the German Competent Authority responsible for cellular therapies – the Paul Ehrlich Institute [...]

That seems like a long time between end of Phase I and beginning of Phase II. They should have started by now.

[Pate]

So that pushes Replicel out til mid-2014 to complete Phase II. They'd want to have some much more decent results than they got in Phase I by that time or they won't get funding for Phase III.

[The Alchemist]

So that pushes Replicel out til mid-2014 to complete Phase II. They'd want to have some much more decent results than they got in Phase I by that time or they won't get funding for Phase III.

Yup. And that's just for a dose ranging study. They'd probably need even another phase II efficacy study once they have the dose dialed in.

These guys are 5+ years out. And that's assuming they even have something that works, which i have some serious doubts about. I'm taking them off my radar. Put them in the bin with follica and acell.

[Person]

Dates available if all goes well...

Aderans = crap
Acell = crap
Histogen = 2018
Replicel = 2017
Allergan Bimatoprost = 2017

The End