Replicel

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  • gutted
    Senior Member
    • Jan 2011
    • 1397

    Originally posted by UK_

    But as you say it probably won't be required because when a hair from donor is transplanted into slick bald the surrounding tissue thickens and behaves as it did when there was hair there before, so by planting cells the body will know what to do which is why replicel had successful phase 1.
    i guess we can only hope. We will know more when they do further trials.

    Comment

    • UK_
      Senior Member
      • Feb 2011
      • 2691

      This study conducted earlier this year shows that DP cells (NOT DSC CELLS) when transplanted through cell therapy work very well with heightened wnt signalling through GSK-3β inhibition, I wonder if Intercytex did it this way?....

      The real treatment will come as a combination of the best possibilities:

      Abstract: 

      It is well known that dermal papilla cells (DPCs) play crucial roles in hair follicle induction. In this study, we examined whether Wnt/β-catenin activation results in maintenance of the hair-inducing ability of human DPCs. Expression of DPC marker genes was maintained under Wnt/β-catenin signalling stimulation by GSK-3β inhibition. Furthermore, human DPCs showed constant hair induction when transplanted with murine epidermal cell fraction. Alu-positive human DPCs were essentially detected adjacent to the reconstructing epidermal structure positive for P-cadherin immunoreactivity. The transplanted human DPCs were abundant in the surrounding dermal sheath portion of the fully regenerated hair follicles. These results support the importance of Wnt/β-catenin signalling in hair follicle induction. This study may provide valuable information to establish a culture method of human DPCs for cell-based therapy.

      Comment

      • greatjob!
        Senior Member
        • Aug 2011
        • 909

        Originally posted by UK_
        I just got my hair cut - **** man.

        Does anyone else here have trouble looking at themselves in the mirror when getting their hair cut?

        I wish I had a hair line that was 2mm above my eyebrows

        fml.
        Ha I feel you man. I hated it so much I learned how to cut my own hair, pretty sad, but Ive gotten pretty good at it

        Comment

        • UK_
          Senior Member
          • Feb 2011
          • 2691

          I know I hope we get an update on when Phase 2 starts real soon.

          Comment

          • JDW
            Senior Member
            • Mar 2012
            • 105

            Originally posted by greatjob!
            Ha I feel you man. I hated it so much I learned how to cut my own hair, pretty sad, but Ive gotten pretty good at it
            same, home hair cutters FTW

            Comment

            • NotDyingBald
              Member
              • Jun 2011
              • 47

              Originally posted by UK_
              I know I hope we get an update on when Phase 2 starts real soon.
              Also good as that, is having some information about 12 months results. Last patient completed his 6 months follow up on Jan 12, so we´ve reached 12month mark for all patients.

              Already e-mailed them asking if they´re going to release some of this results and when.

              Comment

              • UK_
                Senior Member
                • Feb 2011
                • 2691

                Yeah id love to see those too!

                Comment

                • 67mph
                  Senior Member
                  • Mar 2010
                  • 216

                  Originally posted by UK_
                  I just got my hair cut - **** man.

                  Does anyone else here have trouble looking at themselves in the mirror when getting their hair cut?

                  I wish I had a hair line that was 2mm above my eyebrows

                  fml.
                  Every one of us here on this forum, every single one of us!!

                  Just got to remember you're not the only one, does that even help? I'm not even sure of that.

                  So, back to thread, back to Replicel...!

                  Comment

                  • UK_
                    Senior Member
                    • Feb 2011
                    • 2691

                    It is comforting to know that the person cutting my hair is also NW6.



                    This time next year I will be full blown NW6 at the moment I am NW 5.

                    Comment

                    • Kiwi
                      Senior Member
                      • Mar 2011
                      • 1087

                      Originally posted by UK_
                      It is comforting to know that the person cutting my hair is also NW6.



                      This time next year I will be full blown NW6 at the moment I am NW 5.
                      Do you have hopes for anything next year?

                      Comment

                      • 5000
                        Member
                        • May 2012
                        • 33

                        atleast in our prayers we should pray to GOD to help us get rid of this ****
                        forgive us for our sins which made us go bald
                        lets just be hopeful

                        Comment

                        • gutted
                          Senior Member
                          • Jan 2011
                          • 1397

                          Originally posted by 5000
                          atleast in our prayers we should pray to GOD to help us get rid of this ****
                          forgive us for our sins which made us go bald
                          lets just be hopeful
                          looool 2020????

                          Comment

                          • krewel
                            Senior Member
                            • Aug 2011
                            • 187

                            Originally posted by 5000
                            atleast in our prayers we should pray to GOD to help us get rid of this ****
                            forgive us for our sins which made us go bald
                            lets just be hopeful
                            I guess if people didn't spend so much time on praying, many problems would be fixed today. But let's not go there.

                            The only problem I see with Replicel is, weather they are going to be able to compete against Aderans. The two Ji-Gami complexes Aderans has been testing, are working really well. The third one they are testing now may even work better. Unless Replicel is going to reach bigger growth rates, I doubt their succeed. I don't doubt their method works. It does, they showed that in Phase I. These low growth rates are absolutely normal for a Phase I study, or I better say, they don't matter. So I guess no one will be in need of Replicel, as soon as Aderans hits the market.

                            People on forums get discouraged for stupid reasons. The biggest reason is that depressed hairloss-suffering, self proclaimed scientists are sharing stupid rumors like "Replicel is dead" because they didnt see high hair growth rates on their first one study or because that little Trichoscan result didnt look like a bearskin. It's ridiculous.
                            They (people like that self-staging weird Ironman) from Hairsite (please avoid this site) are quoting scientific parts of articles/studies, talk rubbish about is, without noticing, that their own arguments are contradictory, because they don't know what their talking about, making other members of forums unsecure and believe their nonsense.
                            People who've been suffering from hair loss a long time tend to take out their aggressions on the companies, like that Joe some shows ago. It's not right and it's not helping anyone.

                            Aderans is in sight, so is Histogen. They will be very good treatments, as will be Replicel. The only question is, if Replicel is going to be better, because Replicel lays behind.

                            Be reasonable.

                            Greetings.

                            Comment

                            • UK_
                              Senior Member
                              • Feb 2011
                              • 2691

                              Originally posted by Kiwi
                              Do you have hopes for anything next year?
                              Going on holiday in January?

                              Comment

                              • UK_
                                Senior Member
                                • Feb 2011
                                • 2691

                                Bernstein seemed to like the results, a shame you lot didnt.

                                Bernstein Medical offers expert hair restoration in New York, providing advanced treatments for men and women experiencing hair loss and thinning concerns.

                                Comment

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