Replicel
Collapse
X
-
This study conducted earlier this year shows that DP cells (NOT DSC CELLS) when transplanted through cell therapy work very well with heightened wnt signalling through GSK-3β inhibition, I wonder if Intercytex did it this way?....
The real treatment will come as a combination of the best possibilities:
Abstract:
It is well known that dermal papilla cells (DPCs) play crucial roles in hair follicle induction. In this study, we examined whether Wnt/β-catenin activation results in maintenance of the hair-inducing ability of human DPCs. Expression of DPC marker genes was maintained under Wnt/β-catenin signalling stimulation by GSK-3β inhibition. Furthermore, human DPCs showed constant hair induction when transplanted with murine epidermal cell fraction. Alu-positive human DPCs were essentially detected adjacent to the reconstructing epidermal structure positive for P-cadherin immunoreactivity. The transplanted human DPCs were abundant in the surrounding dermal sheath portion of the fully regenerated hair follicles. These results support the importance of Wnt/β-catenin signalling in hair follicle induction. This study may provide valuable information to establish a culture method of human DPCs for cell-based therapy.Comment
-
Ha I feel you man. I hated it so much I learned how to cut my own hair, pretty sad, but Ive gotten pretty good at itComment
-
Also good as that, is having some information about 12 months results. Last patient completed his 6 months follow up on Jan 12, so we´ve reached 12month mark for all patients.
Already e-mailed them asking if they´re going to release some of this results and when.Comment
-
Just got to remember you're not the only one, does that even help? I'm not even sure of that.
So, back to thread, back to Replicel...!Comment
-
The only problem I see with Replicel is, weather they are going to be able to compete against Aderans. The two Ji-Gami complexes Aderans has been testing, are working really well. The third one they are testing now may even work better. Unless Replicel is going to reach bigger growth rates, I doubt their succeed. I don't doubt their method works. It does, they showed that in Phase I. These low growth rates are absolutely normal for a Phase I study, or I better say, they don't matter. So I guess no one will be in need of Replicel, as soon as Aderans hits the market.
People on forums get discouraged for stupid reasons. The biggest reason is that depressed hairloss-suffering, self proclaimed scientists are sharing stupid rumors like "Replicel is dead" because they didnt see high hair growth rates on their first one study or because that little Trichoscan result didnt look like a bearskin. It's ridiculous.
They (people like that self-staging weird Ironman) from Hairsite (please avoid this site) are quoting scientific parts of articles/studies, talk rubbish about is, without noticing, that their own arguments are contradictory, because they don't know what their talking about, making other members of forums unsecure and believe their nonsense.
People who've been suffering from hair loss a long time tend to take out their aggressions on the companies, like that Joe some shows ago. It's not right and it's not helping anyone.
Aderans is in sight, so is Histogen. They will be very good treatments, as will be Replicel. The only question is, if Replicel is going to be better, because Replicel lays behind.
Be reasonable.
Greetings.Comment
Comment