I think Histogen is gonna be the answer .. Their definately going in the right direction. Results so far were promising compared to replicel. Can't wait til it hits the market. Just can't believe how histogen is being dogged here and they actually produced way more visual hair than replicel. Should be all praises especially when replicel disappointed so much but was highly defended here. Replicel would of killed (figure speech) for histogens results. And that was just safety trials. Lol . If exciting news is coming giving they previous release , I'm tuned in!!!!! More optimistic than last week and a little less skeptic. 51/49.
Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering
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I think Histogen is gonna be the answer .. Their definately going in the right direction. Results so far were promising compared to replicel. Can't wait til it hits the market. Just can't believe how histogen is being dogged here and they actually produced way more visual hair than replicel. Should be all praises especially when replicel disappointed so much but was highly defended here. Replicel would of killed (figure speech) for histogens results. And that was just safety trials. Lol . If exciting news is coming giving they previous release , I'm tuned in!!!!! More optimistic than last week and a little less skeptic. 51/49.Comment
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Funny thing that I noticed reading their published paper is that there were actually FOUR injections in each of the four treatment sites (ie sixteen injections total). They keep talking about 'a single injection' but they must mean from a time point of view (ie no follow-up injection).
That also explains why the area responding to treatment looked bigger than 2mm radius. It's because there were actually multiple injections in a square pattern.Comment
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I'm just concerned that the hairs that are thinning now will be damaged beyond repair by the time HSC is released.
What do you guys think?Comment
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I dont know enough about the biology of it, but I remember seeing pictures of follicles at different stages, including the dormant phase. All the necessary components were there, but it just looked shriveled up.
If some scientists claim that all thats needed is the signal to tell the stem cells to get working, then here's hoping HSC can delivery that! Assuming its wnt signals and not something else.
It takes a very long time for a follicle to become dormant. From terminal, to thin, to velus, peach fuzz, and then it continues but the hair doesnt come through the skin. <<<<< If HSC can wake all those up then I'm saved. For the people who have been shiney bald for 5 years or more....who knows. It would be pretty stupid to only be testing it out on thinning patients, so I'm sure histogen will have 'some' news soon enough. They still doing a 3 month update?Comment
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Biggest take-home message for me was:
"Phase I/II shows 46.5% greater increase in total hair count as compared to the Pilot HSC clinical trial at 12 weeks."
Great news!Comment
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Again, note that "increased hair growth" is not the same thing as "created new hairs." What's being referenced in the article is the stimulation of miniaturized and resting hairs, not the creation of new hair follicles. It helps hair you already have, but may not do anything to make up for lost hair.Comment
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But would creating new hair follicles be necessary if the issue is just genetic alopecia? Couldn't we just induce the existing follicles to grow hair?Comment
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