Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[Purple Glow]

Concealers are pretty awesome. I use nanogen. It takes about 30 seconds in the morning to apply, and it looks perfect. No side effects. My barber is amazed as how well it works. That's why I consider a minimum guarantee of no bald spots and just diffuse growth a cure.

[CAlex]

@ DASANI

I dont mean to scare you but your expectations are completely ridiculous about getting 200 hairs cm/2 by any of the current treatments in the pipeline. You may have only begun to thin but histogen isnt due out for at least 4-5 years. You may have progressed to a NW 5 by that time for all you know.

your posts make you sound very young and unaware of how many times a cure has been just around the corner and never reached market.

right now none of the histogen, follica, and aderans are all in their infancy so dont go planning your afro party until they at least get through Phase 2 trials and show their results work on larger areas of scalp and completely bald skin.

A MAJOR part of trials is also dialing the "product" to cost the consumer the most amount of money and make it a needed repeat purchase. Almost of product on the market today(medical/technological) is designed and tweaked to a lower level of quality then was reached in the lab/factory.

Its called Planned obsolescence and histogen will undoubtedly fall into this practice

[DepressedByHairLoss]

I dunno, I think that Histogen's HSC complex will be available sooner than later, maybe just worldwide and not in the U.S. But that doesn't matter to me; I'll travel to the end of the earth to regrow my hair. It will probably take a while to get FDA approval (hell, the FDA is even complaining now about Latisse being used for hair loss!), but at least they're conducting trials in the Far East so that should speed things up. Right now they're in a combined Phase I/Phase II trial to prove that the complex is safe. If they get done with that by this year or next, then its on to Phase III to prove its effectiveness. That's when we'll hopefully really see some good stuff happen. I have more confidence in Histogen than any other company out there right now. Man, if we had more Histogens out there, my confidence for an effective treatment for hair loss would be very high.

[Dasani]

True there has been announcements of a 'cure' before that didn't pan out, but Histogen is the first company to come along with 'real' results. The numbers are there, 57 hairs per cm2 -- from an injection designed to test safety. But of course the only way to know for sure is to wait for the second round of clinical trials. I just hope this stuff compounds, because if it does that's the end of male pattern baldness forever.

[Dasani]

And I disagree about there being a need for dialing the product to make it a repeat purchase. I think this practice will be very much like orthodontics, something most people have done once in their lives and then after completing payments they're done for life with perfect teeth. I think hair restoration will have a similar model

[CVAZBAR]

i stick with what dr cole said about Ari and Histogen, so dont hold your hopes up

Im not expecting Histogen to turn a NW7 into a NW1. I'm hoping for Histogen to help out with halting hair loss and if it can do more, great! We can then combine this with every other option we have. You said this yourself. Dr Cole seems to believe that everyone is expecting complete transformation. As much as I respect the guy, we know how fast he can change his mind.

[UK_]

True there has been announcements of a 'cure' before that didn't pan out, but Histogen is the first company to come along with 'real' results. The numbers are there, 57 hairs per cm2 -- from an injection designed to test safety. But of course the only way to know for sure is to wait for the second round of clinical trials. I just hope this stuff compounds, because if it does that's the end of male pattern baldness forever.

Not exactly - there have been results with similar procedures but they turned out to be unsafe.

If Histogen can prove safety, then I see no reason why we cannot go beyond the current rates of growth seen through the use of repeated treatments/stronger doses; I am more worried about proving this product safe than anything else.

[Kiwi]

Not exactly - there have been results with similar procedures but they turned out to be unsafe.

If Histogen can prove safety, then I see no reason why we cannot go beyond the current rates of growth seen through the use of repeated treatments/stronger doses; I am more worried about proving this product safe than anything else.

I don't care if they can improve graft count or not - what they have now is good enough for me... they should launch that and not be greedy with their first product.

Launch something safe that is better then minox and propecia. Then while they are making millions of dollars launch a better product later on.

Heck thats how the world works now with most things - its business 101. Launch! Get something out the door!!

[UK_]

Kiwi, I totally feel you but safety is something that never really leaves the scope of any stage of clinical trial.

[Kiwi]

yeah don't get me wrong - i'm just saying that if they could make it more powerful don't do it at the risk of delaying a launch and more stringent FDA approval...

in other news I hate my hair today - total downer. i wish my first two transplants worked out better

[Dasani]

I'm sure we're all dying to see what the results are of their phase 2 trials. I'm hoping this treatment compounds. I can't imagine why more doses wouldn't produce more results but we'll have to see.

hypothetical scenario: this treatment is proven to be 100% safe, but doesn't get any more than 57 hairs per cm2 (I don't expect this to be the case but we just don't know for sure until they test it) - do you guys think there would be a market of people who just have naturally thin hair that would be interesting in increasing their hair density with this product? I can't see why not.

[CAlex]

Im not sure why everyone is so sure that the results are compoundable. There is NO way to KNOW that without trials. All I honestly care about is seeing if it stays safe through phase 2 and works on larger areas. ie 5 injections grows the same 57 new hair over 5cm giving 285 new hair. Any compounding effect that will produce further density is OBVIOUSLY of great importance to us but lets just see if it works over larger areas first lol. we can get greedy after that.

If this compound is proven to work over a larger area and is released to market it would be a "cure" for all future young men and women who were headed to future hair loss.

AS soon as they began to notice any hair loss they could just go get a few injections and it would strengthen all the effected hairs. This treatment could be used for all future people just beginning to notice hairloss until a " better" genetic or whatever treatment would be discovered.

anyone being born today wont have to battle hairloss as we have had to do. the hardest part of fighting hairloss is reversing it. in 20 years preventative medicine based on earlier work(todays histogens and follicas) will have hairloss beaten.

[Dasani]

Im not sure why everyone is so sure that the results are compoundable. There is NO way to KNOW that without trials. All I honestly care about is seeing if it stays safe through phase 2 and works on larger areas. ie 5 injections grows the same 57 new hair over 5cm giving 285 new hair. Any compounding effect that will produce further density is OBVIOUSLY of great importance to us but lets just see if it works over larger areas first lol. we can get greedy after that.

If this compound is proven to work over a larger area and is released to market it would be a "cure" for all future young men and women who were headed to future hair loss.

AS soon as they began to notice any hair loss they could just go get a few injections and it would strengthen all the effected hairs. This treatment could be used for all future people just beginning to notice hairloss until a " better" genetic or whatever treatment would be discovered.

anyone being born today wont have to battle hairloss as we have had to do. the hardest part of fighting hairloss is reversing it. in 20 years preventative medicine based on earlier work(todays histogens and follicas) will have hairloss beaten.

Didn't mean to say I was 100% positive this will compound or it will work over larger areas. Yes I agree we should be cautiously optimistic, but optimistic nonetheless. In the clinical trials the HSC injections caused hair regrowth in both the back and the front regions of the head. That's a good sign.

[Dasani]

I'm very much looking forward to their phase 2 results. This upcoming fall/winter is a very exciting time. We're going to see results from Histogen's phase 2 clinical trails, replicel's first phase of clinical trails, and probably Aderans latest findings.

[CAlex]

I hope you are not losing sight of the still very real possibility that none of the current big hopes(histogen, follica ,aderans, replicel) will ever make it to market. Be it because safety concerns that could arise or the results are not consistent enough.

It just always worries me when I see too much enthusiasm from young posters. Im sure everyone on here is looking forward to phase 2 results but It could go from exciting to heartbreak overnight. All Im saying is be cautious with your hopes.

Ive just run into a few younger guys on forums get their expectations way out of whack and then spiral into pretty bad states of depression when new drugs/companies went belly up.

All that being said histogen keeps us decently informed and their results so far are very promising.