Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

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  • CVAZBAR
    Senior Member
    • Dec 2010
    • 443

    Originally posted by UK_
    Well the treatment would fail clinical trial if it created scar tissue, so you wouldn't even have the chance to use it. I doubt we can just write it off on the basis of our 'clinical knowledge'.

    Follica are a highly secretive company, I doubt anyone could even come close to mimicking the process they have spent all this time working on, I do believe they have something.
    That's the problem with Follica. They don't say shit, so it's really hard to know anything. They release bits of news and nothing more. I wasn't able to listen to the whole shit but they are using
    a compound and according to Joe, they did not want to say what it is, for obvious reasons. Nobody is saying they have the cure, this is just info for the public. It's always good to hear anything that comes out of them, since they stay quiet. We are so used to ****ing promises and companies talking loud but never bring shit. Follica has made some valuable discoveries so we know they are not playing. They might have something like you say but Who knows how close they are to something big.

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    • UK_
      Senior Member
      • Feb 2011
      • 2691

      Originally posted by CVAZBAR
      That's the problem with Follica. They don't say shit, so it's really hard to know anything. They release bits of news and nothing more. I wasn't able to listen to the whole shit but they are using
      a compound and according to Joe, they did not want to say what it is, for obvious reasons. Nobody is saying they have the cure, this is just info for the public. It's always good to hear anything that comes out of them, since they stay quiet. We are so used to ****ing promises and companies talking loud but never bring shit. Follica has made some valuable discoveries so we know they are not playing. They might have something like you say but Who knows how close they are to something big.
      Are there any Phase I results? I know they're v secretive but we're sure to see the results of the impending Phase II half-way point right?

      If they really had something remarkable then you'd expect them to voice their results to potential investors. How would information for investors differ to that of the information they provide for potential consumers?

      Comment

      • Losing_It
        Member
        • Jun 2011
        • 88

        Well i don't understand the secrecy. You would imagine if they had successful Phase 1 results they would have announced it. However, the fact that they are in the Phase 2 remains promising, lets just hope they make it through this Phase as there will be a 70% chance that Phase 3 will be successful.

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        • UK_
          Senior Member
          • Feb 2011
          • 2691

          Originally posted by Losing_It
          Well i don't understand the secrecy. You would imagine if they had successful Phase 1 results they would have announced it. However, the fact that they are in the Phase 2 remains promising, lets just hope they make it through this Phase as there will be a 70% chance that Phase 3 will be successful.
          I know... if they've been so successful then where are Phase I results?

          Surely if someone wanted to invest [at this point] they'd need to see current progress, without it you can't sell added share value and raise capital to progress research.

          Comment

          • Losing_It
            Member
            • Jun 2011
            • 88

            So we can safely assume then that the Phase 1 results were not that impressive. The lack of information probably means that its a dud.

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            • LarryDavid
              Member
              • Feb 2011
              • 41

              Jesus, did you even read the histogen page?

              "The Company is scheduled to begin a Phase I/II clinical trial of its Hair Stimulating Complex (HSC) in Singapore in Spring 2011"

              They started phase I and II this month. On the histogen page you can see the results from the preclinical trials which are impressive.

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              • Sogeking
                Senior Member
                • Feb 2011
                • 494

                Originally posted by LarryDavid
                Jesus, did you even read the histogen page?

                "The Company is scheduled to begin a Phase I/II clinical trial of its Hair Stimulating Complex (HSC) in Singapore in Spring 2011"

                They started phase I and II this month. On the histogen page you can see the results from the preclinical trials which are impressive.
                Larry we are talking about Follica. I know its not the right thread or topic but the conversation just went there.
                UK they have passed Phase 1 but maybe they are going through with Phase 2 just to justify projcet costs and inital investments. Maybe the results are minimalistic but they still want to milk some money out if it.
                But this is just inexcusable speculation from my part. However I am a pessimist.

                Comment

                • LarryDavid
                  Member
                  • Feb 2011
                  • 41

                  ah ok sorry!

                  Regarding Follica: In case they have enough money (i dont know that) why would they publish their phase 1 results?

                  Comment

                  • UK_
                    Senior Member
                    • Feb 2011
                    • 2691

                    They always state in interviews "for business reasons we can't go into too much detail" - I suppose releasing data on trials successful or not is going pretty heavy into detail. I mean look at how much Histogen revealed about their process just by releasing trial data from Phase I.

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                    • RichardDawkins
                      Inactive
                      • Jan 2011
                      • 895

                      well sorry but i would be more shocked if they would release stuff all the time. The worst companies in the past were those who gave away too much.

                      Comment

                      • Flowers
                        Senior Member
                        • Feb 2011
                        • 254

                        Yeah maybe follica just doesn't wanna constanty update because when companies do that you have reactions like histogen has. Too much pressure to follow up a phase/ trial that people find insignificant or too promising. Follica probably just wanna get the work done (if they're really onto something) and then make the announcement that they have it. Then they'll get all the attention and more that announcing trial results for years could give them.

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                        • RichardDawkins
                          Inactive
                          • Jan 2011
                          • 895

                          Same goes for Histogen. I doubt that we will hear anything in the near future except when they finish certain key points

                          But one thing is for sure here, all of them have shown regrowth and sustaining hair :-) but the only bad thing is the waiting time. But the relief will be great

                          Comment

                          • CVAZBAR
                            Senior Member
                            • Dec 2010
                            • 443

                            Originally posted by UK_
                            Are there any Phase I results? I know they're v secretive but we're sure to see the results of the impending Phase II half-way point right?

                            If they really had something remarkable then you'd expect them to voice their results to potential investors. How would information for investors differ to that of the information they provide for potential consumers?
                            Like I said, they didn't speak about trials. Don't expect to hear
                            much from them. It's all "business" with them and secrecy due to investors. Spencer can't even get interviews with them. Spencer constantly says that if any news would come, he would hear about it first. I guess that's why they reported this on the show. Regardless, we don't know if it's minor or major but we know they got something going on.

                            Comment

                            • CVAZBAR
                              Senior Member
                              • Dec 2010
                              • 443

                              It would be nice if Joe could post his news here. Tell us exactly what he heard. Joe is the main reason why I listen to the show. His weekly news. Help us out Joe!

                              Comment

                              • UK Boy
                                Senior Member
                                • Apr 2011
                                • 240

                                Scientists find a 'cure' for grey hair
                                By Ceri Roberts, Jun 17, 2011

                                If you're fed up with dyeing your hair to hide those grey roots, we've got some good news.

                                Scientists have identified a protein called 'wnt' that's responsible for the production of colour in each of our strands of hair.

                                In a series of experiments they discovered that this protein is key to hair retaining its colour and it also stimulates hair growth and produces new hair follicles.

                                As a result, we could look forward to the development of drugs, lotions and shampoos that raise levels of wnt - and restore white or grey hair to its original colour.

                                And as the same protein is responsible for hair growth, boosting levels of wnt could also help to prevent the thinning that often occurs with age.

                                Writing in the journal Cell, the researchers from New York University's Lagone Medical Centre explain that the protein wnt kickstarts a chain of reactions that lead to stem cells in the scalp maturing and producing the pigment that gives hair its colour.

                                They have yet to discover whether it's a fault in this system that causes us to go grey.

                                Most Britons notice their first grey hair at around the age of 25.

                                It's thought that genetics determine if and when a person will go grey, but stress, smoking, alcohol, poor diet and even dyeing your hair blonde are all thought to speed up the process.

                                I posted this on it's own thread but thought I'd also add it on to here because it seems to me to back up the science behind Histogens procedure.

                                These researchers are confirming that WNT is involved in stimulating hair growth and the production of new follicles. It's good to see that it will also help with greying of hair. I also think it's great to know other researchers are working with WNT in regards to hair issues and they talk about bringing out a product that will increase WNT levels. One product that could basically deal with the two main problems people suffer with regarding hair (greying and hair loss) would be a huge deal.

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