Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[RichardDawkins]

A "cure" is well pretty simple. There are two ways or lets say two and a half ways.

1) Surgical : Hair multiplication in vivo (etract some stem cell tissue and let it regenerate in the donor area)

2) Injection : Get the stem cells to work together again

3) Plucked hairs : are a mox between the two of them

4) grow complete follicles in a petri dish and transplant them

The magic pill will never come, you should say goodbye to this. There wont be a pill which reverses your hair loss completely

[CVAZBAR]

Speaking of possible cures, what's the deal with that dude that Spencer was going to interview? I can't remember who this guy is but he's been saying that he was going to interview this guy and I think it was something about cloning. I may be wrong but does anyone know or remember this?

[ResearchNeverfails]

MPB cured Read my post

Read my post science already backs it they just didn't know the trigger i found the trigger.

[CVAZBAR]

Read my post science already backs it they just didn't know the trigger i found the trigger.

What the hell are you talking about?

[Follicle Death Row]

Don't know how I didn't see this before but here's another talk from Ken Washenik albeit from this time last year. The promising thing is the FDA phase 3 stage seems like it will only be 18-24months!!! On the market at the beginning of 2014 supposedly. It's nice that Histogen and Aderans are in a race.

http://www.aderansresearch.com/presentation/

[CVAZBAR]

Don't know how I didn't see this before but here's another talk from Ken Washenik albeit from this time last year. The promising thing is the FDA phase 3 stage seems like it will only be 18-24months!!! On the market at the beginning of 2014 supposedly. It's nice that Histogen and Aderans are in a race.

http://www.aderansresearch.com/presentation/

That's great news. 2 and half years away! Is Aderans growing new hairs or just reawakening dormant follicles? This is non surgical right or is there scarring also?

[UK_]

http://www.hairway.org/show.aspx?id=670&cid=79

Website has a nice biopsy pic.

[Follicle Death Row]

That's great news. 2 and half years away! Is Aderans growing new hairs or just reawakening dormant follicles? This is non surgical right or is there scarring also?

Non surgical as far as I know. Tiny needle to extract the required dermal and epidermal cells. Well that's what I got from it anyway though I might be wrong. They did their proof of concept thing ages ago and the timeline seems to be sound and they're not just winging it like I fear Histogen are. I think it looks like they're reawakening dormant follicles but I again that's just what I thought from the presentation. Still don't know what the cosmetic end result is going to be like. No one yet knows what this technology can and can't do. I think it might run a bit behind.. Yeah, 2 and a half years, forgot about the last year to be cleared by the FDA after phase 3, but yeah beginning of 2014. I had been thinking end of the decade myself (That's what Dr. Bernstein had been touting) but I didn't actually know that they were deep in phase 2. I had assumed they'd be another 3 years at phase 2, followed by a 5 year phase 3, if they got that far. I wonder are they feeling as boisterous a year on from that presentation. Hopefully Spencer does another interview with Ken Washenik in the near future for a progress report.

[Follicle Death Row]

http://www.hairway.org/show.aspx?id=670&cid=79

Website has a nice biopsy pic.

Nice find. I think my expectations for Histogen are that it's still a long way off but that it's going to be key for those that are just beginning to miniturise and lose some hair. This stuff could potentially hold it off forever but I think I might be pretty damn bald when it does come to market.

I'd like to think that in the future Histogen will be the medical treatment so to speak and Aderans will be the transplantation but the lines are blurred. Maybe they can be used synergistically. Kids today won't have to worry about going bald that's for sure.

[CVAZBAR]

Nice find. I think my expectations for Histogen are that it's still a long way off but that it's going to be key for those that are just beginning to miniturise and lose some hair. This stuff could potentially hold it off forever but I think I might be pretty damn bald when it does come to market.

I'd like to think that in the future Histogen will be the medical treatment so to speak and Aderans will be the transplantation but the lines are blurred. Maybe they can be used synergistically. Kids today won't have to worry about going bald that's

The way Spencer speaks, it seems that he actually has more faith in Histogen than anything else. To bad none of this is near.

[CVAZBAR]

Nice find. I think my expectations for Histogen are that it's still a long way off but that it's going to be key for those that are just beginning to miniturise and lose some hair. This stuff could potentially hold it off forever but I think I might be pretty damn bald when it does come to market.

I'd like to think that in the future Histogen will be the medical treatment so to speak and Aderans will be the transplantation but the lines are blurred. Maybe they can be used synergistically. Kids today won't have to worry about going bald that's for sure.

[QUOTE=Follicle Death Row;30734]

The way Spencer speaks, it seems that he actually has more faith in Histogen than anything else. To bad none of this is near.

[Follicle Death Row]

I was thinking about the 57 hairs in 1cm2 Dr. Ziering mentioned. At 2.2 hairs per follicular unit that's almost 26FU/cm2. Now I'm sure that wasn't on a completely bald scalp but anyway let's suppose initially Aderans can do something similiar.

If one of those treatments could give you 25FU/cm2 over an area of 240cm2 (norwood 6) you could then add 6,000 by FUE (that would thin the donor by about 30&#37. Those 6,000 all over 240cm2 would give an additional 25FU/cm2 resulting in a combined total of 50/cm2. Let's suppose you weight those 6,000 grafts and in the crown which is 100cm2, you go for 40FU/cm2. Now if you chop the mid scalp and front into 80cm2 and 60cm2 sections respectively (100+80+60) you could have 50FU/cm2 in the mid scalp and almost 67FU/cm2 in the frontal section. I think that in the early days of Histogen and Aderans this might be the best form of attack for those that are heading towards norwood 6 territory. You could do 3 2000 FUE sessions in a calender year. That would be beat the snot out of any 9,000FU for 3 strips and a stupid smiley on the back of your head which is currently the standard today.

Of course as hair cloning/multiplication advances and becomes cheaper you can go for top ups to add more density. Perhaps the Acell autcloning/plucking thing might be up and running. Looks like we'll have some decent options in 5 or 6 years. A synergistic use of treatments will probably give the best results until they have this thing cracked once and for all.

[CVAZBAR]

I'm really hoping for Histogen to stop progression. That will set up everything else. Sooner or later you will get your hair back.

[HairTalk]

Kids today won't have to worry about going bald that's for sure.

That might be a bit too optimistic, at this point.

[UK_]

Yeah we should get our expectations in check, I can't see this growing hair on completely bald scalps tbh might work well if transplanted hairs are dipped in HSC, then planted to increase density, survival and possibly grow new surrounding hairs from the stimulation of the transplanted stem cells.