Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[CVAZBAR]

No, I haven't. But it's always something that should be considered when the "before" pictures have a fair amount of hair in them to begin with:

You should ask. That would be a good question because Doc z seems to have a lot of faith in this product. I wanted to ask you a question G. What do you believe in? I mean do you have faith in any product? You are very active in this site but you rarely show optimism in anything.

[UK_]

Hint: A hair follicle cycling from telogen to anagen phase isn't really "new" hair. And nearly all (normal) hairs produced as the follicle transitions from telogen to anagen last at least two years.

But how do you know if that is happening? The literature regarding the mechanism behind WNT 7A unfortunately does not support the hypothesis you are proposing, you also have no objective basis upon which to make such an assertion, a hypothesis should atleast have some justification. If the researchers believe this product is signalling stem cells already in the scalp to produce new hairs per follicular unit, then that is a contention I would prefer to support as researchers only make such assertions if they are theoretically plausible whence referring to the literature, which is exactly what Histogen do.

WNT 7A has been shown in animal models to GROW TOTALLY NEW HAIRS IN BALD MICE - (LITERALLY MICE WITH NO HAIRS). It did not achieve this through ANY of the mechanisms you are proposing here, I suggest you do a little research on what WNT proteins really are, and the power behind them, these arnt your run-of-the-mill compounds believe me.

[UK_]

No, I haven't. But it's always something that should be considered when the "before" pictures have a fair amount of hair in them to begin with:

So what? The study was conducted on patients right up to NW6, who did responded to treatment, so if this product does come through, we could have a potential treatment for ALL stages of hair loss. What you see in those pictures is not of importance, your eyes will never tell a clearer story than the statistical measurements/results that form the real substance of the success of this study.

If this is the method you are using to subvert the results of HSC, then please exit this thread and visit:

http://www.alibaba.com/product-gs/300802745/Quick_hair_regain_only_7_days.html

According to your logic, this product has more viability than HSC.

[RichardDawkins]

@gmonasco : Its easy, those hairs have been "dead" before so it would be highly unlikely that a small injection could get them to actually start their cycling again (considering HSC would fail as you put it)

And the other thing is, even with regards to your concearns, to me it seems that the worst case would be hair, which succumbs to DHT again after the initial amount of years, it took this hair to succumb in the first place.

But this life span would be also expanded becaus DHT concentration decreases over years.

[GBB]

@gmonasco : Its easy, those hairs have been "dead" before so it would be highly unlikely that a small injection could get them to actually start their cycling again (considering HSC would fail as you put it)

And the other thing is, even with regards to your concearns, to me it seems that the worst case would be hair, which succumbs to DHT again after the initial amount of years, it took this hair to succumb in the first place.

But this life span would be also expanded becaus DHT concentration decreases over years.

Amidst all this happy talk (and I sincerely do believe Histogen has the pieces to the puzzle), I am really worried that there has been no news about the Singapore trials till date. I read somewhere that it starts in May now. The Web site still says spring though. Isn't May summer? The trials have already been pushed back twice, and we really don't know whats going on.
I had received a prompt reply from Histogen when I had written to them earlier, of late though, information is a little hard to get.

Also, as someone pointed out earlier, a roughly 40% increase in hair count happened to the best responder. If the average increase in absolute hair count was around 15%(according to the graph), what was the increase in the number of terminal hairs? Do people with more advanced stages of hair loss respond any better or worse?

[Sogeking]

Actually May is in spring. Spring has started yesterday and will end on 21st of June. Well that is by calendar, astronomical spring started on Mar 20 @2321 UTC. And meterological on 1st of March .
However they were constantly saying early spring. For me that is end of March and April... And now we hear it is May?

Anyways I'm concerned about this silence myself.
So basically I just want them to start with the clinical trials. I guess we'll have to wait for May...

The next clinical trial of HSC is currently in planning stages, and is scheduled to begin in Singapore in early 2011, with plans for pan-Asian approval in 2014. Estimated U.S. market introduction of the injectable for hair regrowth in the treatment of male pattern baldness is 2015, with potential for earlier introduction in certain identified countries.

[GBB]

Well, actually sometime last year they had said Feb 2011 in an email.
Anyway, Doc Z has also dissapeared from this thread..

[CVAZBAR]

Well, actually sometime last year they had said Feb 2011 in an email.
Anyway, Doc Z has also dissapeared from this thread..

Well hopefully he is lagging because he has the cure and doesn't have the words to express his joy haha. Honestly, I don't have a good feeling about this. Im hoping someone will come out with the cure out of nowhere. Follica seems to be very quiet and rarely share anything. Aderans as well. Histogen is putting pressure on everyone, so it seems logical to think everyone else might be right behind or ahead, who knows. Maybe not. Im just tired.

[HairTalk]

I do think Dr. Ziering should come on to share information with us, even if nothing new is available (at least tell us that's the case). It's unfortunate everyone's sitting around in uncomfortable expectation, as it was announced something would be shared by this time.

[UK_]

I havn't got a good feeling about this either lol.

[Mojo Risin]

It's pretty obvious that nothing is going to be announced.

Hey guys, guess what, we're still 5 years away !

So tired of all that bullshit.

[CVAZBAR]

We need Spencer to find out what's cracking since he has the connects.

[GBB]

We need Spencer to find out what's cracking since he has the connects.

Absolutely. Any news whether good or bad will be appreciated.

[gmonasco]

Maybe the test subjects sprouted so many new hairs that it's taking them an extra-long time to count them all ...

[UK_]

Or maybe it was so successful it hit market on monday and the doctors are rushed off their feet curing hundreds of bald singaporean nationals.

I was thinking of going to sleep for five years, atleast I wouldn't have to be consciously aware of all this hit/hope n miss all the time and it would seem like no time has past, its the fastest route to knowing.