New Italian DGLA poduct - due 2017

[burtandernie]

Yes I think all hope, but do we know equol really will work as well as fin at reducing DHT? Is there proof in humans it stops hair loss and lowers DHT as much as fin? It has to be as powerful and not have the sides fin does. That is a tall order for anything

"Equol=Fin, DGLA=minox"

[Hairbrain]

Yawn
How many of these type of threads already exist here?

[kuba197]

Until there is evidence it does anything at all its a bit silly honestly to even really discuss or pin anything on this. Tons and tons of things like this have come and gone whether good intentioned or not a lot flat out dont end up working. I hope it does, but realistically use what exists now and dont pin hopes on what could happen. 10 years ago they thought a better treatment/cure was just around the corner, and today there is nothing new

I understand your reasoning. However in this possible treatment, we can see s-equol which was never tried by any company as a topical. And the discvovery about pge1 is an accident just like minox( Dr. Brotzu also mentioned that this beat minox in terms of regrowth).
Hey, this is not cure but treatment without sides? Equol=Fin, DGLA=minox? I hope!

[burtandernie]

Until there is evidence it does anything at all its a bit silly honestly to even really discuss or pin anything on this. Tons and tons of things like this have come and gone whether good intentioned or not a lot flat out dont end up working. I hope it does, but realistically use what exists now and dont pin hopes on what could happen. 10 years ago they thought a better treatment/cure was just around the corner, and today there is nothing new

[vipalex]

What do you thiink about this product?

Hi Kuba, like all products a lot of good words but practically 0 facts.

Morris

[kuba197]

Hi guy, don`t trust Italian forum, they are 30 years behind.
P.S
I am italian and I use to check all forum like bellicapelli, ieason Harsite.
From now the best one is only the bald truth
Morris

What do you thiink about this product?

[vipalex]

Hi guy, don`t trust Italian forum, they are 30 years behind.
P.S
I am italian and I use to check all forum like bellicapelli, ieason Harsite.
From now the best one is only the bald truth
Morris

[kuba197]

http://www.ieson.com/topic.asp?TOPIC_ID=70401&whichpage=8

Group buy

[burtandernie]

Yeah that would be great, and certainly amazing to equal propecia. Also you would not need to pay a doctor/derm to go back every time for refills or see them periodically. That is why I have my doubts this will work, and its hard to see it equaling the effectiveness of propecia IMO. So many topicals have come and gone its getting pretty hard to actually think another one is going to be some magic bullet.

[kuba197]

If this lotion works as is told, it will be cure for me ( I am very thick nw1,5-2).
Finasteride without sides. And some regrowth would be a great addition.

[burtandernie]

A new mpb treatment isnt worth anything if it has no evidence it works. Not even worth posting until it has results showing it works. You can sit around all day playing theory craft on what could or should work for mpb, but a lot of it doesnt. Not worth even typing out more speculation on it. It probably wont work anyway

[rbrown]

They're trying to get a lab to mix the lotion! I'm only reading via Google translate. Is there someone speaking Italian that cann keep us up to date?

You are right.The Italian forum members are trying to group buy the ingredients for the lotions and then contact a lab or pharmacy that can make the lotion for them following the inventors patents. These are the inventors patents with the formulas inside:

The lotion containing pge1:

https://www.google.com/patents/WO2013171668A1?cl=en&hl=it&dq=brotzu

The process:
Example 1

Three solutions are prepared as follows: 1 m! of equal is diluted in 1 ml of ethanol and the solution is brought to 10 ml with water;

1 mg of PGE1 in 1 ml of ethanol brought to 10 ml with water;

2 g of carnitine in 10 ml of water.

The above three solutions are placed in a sonicator together with 10 g of phosphatidylcholine (Lipid S75 Human-grade) and sonicated for a sufficient time to obtain liposomes with diameter of less than 100 nm.

The liposome solution thus obtained is poured into an aqueous solution of polylysine 40 - 100 MW (0.01 mg/10 ml) and constantly stirred for 30 minutes. The solution thus obtained can be used directly on the scalp at least once daily The results of the hair loss cessation can already be observed after just 7 days and the first new hair regrowth results between 45 and 90 days.

Example 2

Three solutions are prepared as follows:

1 ml of equol is diluted in 1 ml of ethanol;

1 mg of PGE1 in 1 ml ethanol;

2 g of carnitine in 2 ml of ethanol;

The above three solutions are placed in a sonicator together with 10 g of phosphatidylcholine (Lipid S75 Human-grade) and sonicated for a sufficient time to obtain liposomes with a diameter of less than 100 nm.

The ethanol is completely evaporated and the liposomes obtained are placed in contact with 5 ml of a polylysine 40-100 MW (0.01 / 10 ml) solution. The liposome solution thus obtained is poured into an aqueous solution of polylysine 40 - 100 MW (0.01 mg/10 ml) and constantly stirred for 30 minutes then adding 5 ml of buffered water or of saline solution (NaCl 0:9/100 )

Characterisation of liposomes

The diameter of the liposomes was found to be 60 nm on average with polydispersity index equal to 0.2

The amount of PGE 1 in the liposomes following purification is in the range of 30- 50 pg/ml while the amount of carnitine is between 0.05 and 0.2 mg/ml.

The liposomes were characterised in terms of size, polydispersity index (PI) and zeta potential respectively by means of Photon Correlation Spectroscopy (PCS) (dimensions and PI) and M3-PALS (Phase Analysis Light Scattering), which measures the electrophoretic mobility of the particles in a thermostated cell, (zeta potential) using the Zetasizer nano (Malvern Instrument, UK).

The lotion containing dgla:

https://www.google.com/patents/WO2015170247

And this is the company that will market the lotion presumably by 2017:

http://www.fidiapharma.com/it/l-azienda/,66

Dr.Brotzu answers forum members questions(link in italian)

http://calvizie.net/documento.asp?args=27.1.1302

[tom4]

They're trying to get a lab to mix the lotion! I'm only reading via Google translate. Is there someone speaking Italian that cann keep us up to date?

[rbrown]

Did i get this right?So the PGE1 cream that Dr. Brotzu used can grow hair but he does not want to make the name of that cream public because he wants to make money with his own product that uses DGLA.

[kuba197]

http://www.ieson.com/topic.asp?TOPIC_ID=66178&whichpage=61

Rumour says it would be available in december.