Thank you for the heads-up.
If anyone has any idea on which vehicle would work best for the permeation of scalp.
I know that antifungal medications are used as topical ointments on all outer surfaces of the body except for the nails and the scalp, for which tablets must be taken to provide the necessary delivery to target tissues. So sad that the scalp is apparently as tough as nails for medications to penetrate. TOUGH AS NAILS ...
I think I've hacked it
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Hi FGF11, this question is for you:
This is off-topic of antisense oligonucleatide injections but would you please give me an opinion about my trans-dermal delivery vehicle for Tofacitinib Citrate.
I am currently using 50% Ethanol, 20% water, 20% phosphatidylcholine micelles (liposomes) and 10% propylene glycol by volume.
I rub it all in pretty well, but believe that there is plenty of room for improvement of delivery.
How about perforating stratum corneum a little with 0.5-0.8 mm dermastamping once a week then hold off the application of Tofacitinib for a day after? How much do you think that increases the transdermal delivery in the couple of days following the perforation?
I would rather not use the dermastamper and just use a reliable vehicle of course.Leave a comment:
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He is not arrogant. He is young and learning. If a thousand PhD's can't figure AGA I doubt this guy can but hats off for making an effort. He is a college student so cut him some slack. Some here seem to complain if a person comments and fails to solve baldnerss....yikes, tough crowd I would say.Leave a comment:
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It is desperation more than arrogance. People have been claiming the same for thousand of years.
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The arrogance of the title of this thread never ceases to amuse me.Leave a comment:
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I'm a molecular biologist, and what FGF11 says he did is beyond the scope of what you can do on your own. Plus, he left out critical details, like the specific DNA sequence he used. Plus, there's no proof, just some text from a random stranger on a hair loss site. There's nothing to see here, except nothing going nowhere.
Thanks.
P.S. look at me username before respondingLeave a comment:
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Hey bej , this is a link from a hairloss 2020 there is a discussion started by a guy name Roman about 3a-HSD enzymes being a diamond in the ruff , you have any input, thanks
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really FGF11, your not coming back?
with all respect, if your gone because some people here are idiots then maybe you could toughen up a little and get back in the game.
If it's another reason then that's ok but we still hope you come back.Leave a comment:
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I'm a molecular biologist, and what FGF11 says he did is beyond the scope of what you can do on your own. Plus, he left out critical details, like the specific DNA sequence he used. Plus, there's no proof, just some text from a random stranger on a hair loss site. There's nothing to see here, except nothing going nowhere.Leave a comment:
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HEY guys, FGF11 has spread his knowledge to us.Now we know when it consist, what is needed for to produce , how to produce it .
And now that we know all this can we make and try it ourselves?
what do you thinkLeave a comment:
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I hope he comes back
If he doesn't it's only because it didn't workout.. His protocol is very cutting edge you knowLeave a comment:
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