Updated Research and Knowledge - Cutting Edge

[tiktok]

The oleuropein extract would be ideal, and I wouldnt encourage anything else. You need the extract, not the leaf. Theres not a whole lot of brands out there that make oleuropein in extract form. Its a pain but it's worth it imo.

It's a standardized extract without all the filler of other pills, so less chance of precipitate - seems ideal.

[karxxx]

hi Chemical

What , medicine, please can I use ?
Oleuropein into the liquid mixture containing minoxidil ?
How oleuro mg daily pill ?
Additional additives ?finastreid,avodard,peptipe...?

[Chemical]

I just clicked the link and saw that it is standardised extract. It's perfect. And it's in frickin liquid form! Next time I'll reply when I'm sober - sorry about that.

@medium

If you can get your hands on the liquid form or a ready made tincture, you can mix it with emu oil instead of buying ethanol + propylene glycol.

[Medium]

Thanks, Chemical.
I'll definitely get this solution. I can take it emu oil works much better than castor oil for dissolving the stuff?

[potato1987]

explanation

Can someone explain in simple terms what this product might achieve?

[Chemical]

hi Chemical

What , medicine, please can I use ?
Oleuropein into the liquid mixture containing minoxidil ?
How oleuro mg daily pill ?
Additional additives ?finastreid,avodard,peptipe...?

Oleuropein mixed into the liquid minoxidil solution. Only the liquid.
No oral oleuropein. Emu oil mixed with the oleuropein + minoxidil helps the minoxidil absorb better and is easier to apply. I'd avoid finasteride and any other drugs/medication for hair loss. Unless of course you know what youre doing and want to experiment.

Thanks, Chemical.
I'll definitely get this solution. I can take it emu oil works much better than castor oil for dissolving the stuff?

Emu oil doesnt help for dissolving but does supposedly permeate the skin better and acts as a carrier/vehicle. Its also an anti-inflammatory/(mild 5ar inhibitor?) which means you can stack it with ketoconazole/mico if you're using them frequently.

Can someone explain in simple terms what this product might achieve?

This helps you regrow hair if you're lucky.
It works by reducing DKK1. DKK1 prevents your hair from growing. And it increases growth factors like IGF-1, KGF, HGF and BetaCatenin. I wouldnt recommend this stack for beginners as it does require you to mix stuff.

update:

I've officially stopped the treatment since two weeks ago because I cant be bothered to wash my hair everytime I use the mixture. It dries up into a semi hair wax consistency that is a pain to wash out. I also got my miconazole nitrate a week ago, which I've been using 3 time a day, toothpaste sized amounts, and I've noticed my left side where I've been concentrating the regimen is seeing a dozen or so stubble follicles. When I touch that area its like I'm touching my beard.

This could be a residual effect of the treatment or it could be mico, I cant tell. If it is the mico then the theory that Estrogen Receptor inhibiting hair growth is plausible and tamoxifen will definitely work. This warrants further investigation. I'm still waiting for my minox, which is taking ages to arrive. I'm going to dissolve only 2 oleuropein capsules in the minox this time around and I'll try that for a month straight just to see if there really is a biphasic effect. Last time I got carried away thinking more was better.

[InBeforeTheCure]

This may interest you.

Hair follicles have characteristic sizes corresponding to their cycle specific stage. However, how the anagen hair follicle specifies its size remains elusive. Here, we show that in response to prolonged ectopic Wnt10b-mediated β-catenin activation, regenerating anagen hair follicles grow larger in size. In particular, the hair bulb, dermal papilla and hair shaft become enlarged. While the formation of different hair types (Guard, Awl, Auchene, and Zigzag) is unaffected. Interestingly, we found the effect of exogenous WNT10b was mainly on Zigzag and less on the other kinds of hairs. We observed dramatically enhanced proliferation within the matrix, DP and hair shaft of the enlarged AdWnt10b-treated hair follicles compared with those of normal hair follicles at P98. Furthermore, expression of CD34, a specific hair stem cell marker, was increased in its number to the bulge region after AdWnt10b treatment. Ectopic expression of CD34 throughout the ORS region was also observed. Many CD34 positive hair stem cells were actively proliferating in AdWnt10b-induced hair follicles. Importantly, subsequent co-treatment with the Wnt inhibitor, DKK1, reduced hair follicle enlargement, decreased proliferation and maintained proper hair stem cell localization. Moreover, injection of DKK1 during early anagen significantly reduced the width of prospective hairs. Together, these findings strongly suggest that a balance of Wnt10b/DKK1 governs reciprocal signaling between cutaneous epithelium and mesenchyme to regulate proper hair follicle size.

Link to paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383245/

[potato1987]

Thanks for the response,
Would it do any good without minox? minox (and I know there are doubters, gave me puffy eyes and reduced collagen). I wouldn't lie about it and nor would others. I didn't know it was a symptom I just thought it was lack of sleep but the bags got darker and my skin got thinner the longer the weeks went on.

[SriHanuman]

The mice study seems great! I am going to go ahead and use

http://www.amazon.co.uk/Herb-Pharm-Extract-Liquid-29-6ml/dp/B001E0X2EG/ref=sr_1_1?ie=UTF8&qid=1449612675&sr=8-1&keywords=herb+pharm+olive+leaf+extract+liquid+29.6ml+1floz

with tretinoid as it increases absorption. If it works similar on humans I can expect great results...

[SriHanuman]

F****** double post

[potato1987]

Sorry what does this mean?

[Eire1980]

The mice study seems great! I am going to go ahead and use

http://www.amazon.co.uk/Herb-Pharm-Extract-Liquid-29-6ml/dp/B001E0X2EG/ref=sr_1_1?ie=UTF8&qid=1449612675&sr=8-1&keywords=herb+pharm+olive+leaf+extract+liquid+29.6ml+1floz

with tretinoid as it increases absorption. If it works similar on humans I can expect great results...

Can someone confirm that the liquid in the amazon link is the stuff to use..if so how much would you use daily..appreciate the feedback

[SriHanuman]

Sure it is, it is olive leaf extract, so it contains oleuropein. I will use it enough so it covers the area. This is test and trial... Will report in few months.

[Eire1980]

Sure it is, it is olive leaf extract, so it contains oleuropein. I will use it enough so it covers the area. This is test and trial... Will report in few months.

Thanks much appreciated

I see others have asked before but in simple terms how is this meant to work? ..thanks

[joshuk]

hi just posted to say thanks to chemical for an indepth look at wnt/dkk1 channels and also do you think this http://www.amazon.co.uk/gp/product/B...ilpage_o00_s00 would be suitable to use as a topical im also using CB-03-01 which would help with DKK1 if i read it properly.