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Pantheon is a company focused on developing human cell based technologies for the treatment of wound and creation of a human skin test platform. The company was formed after the dissolution of Aderans Research Institute. The company has developed the ability to generate fully functional human skin from tissue culture expanded scalp derived stem cells. The generated skin contains epidermis, dermis, hair follicles, sweat glands, sebaceous glands, nerves, arrector pili, and adipose.
In Dr. Wu Xunwei's leadership, the Biological Technology Co., Ltd. has been dedicated to the skin team for many years l we Ji'nan pan, and achieved a major breakthrough, our main goal is to develop cell techniquefor the treatment of sores, bald and the establishment of human skin testplatform model. We have developed a human hair cells from tissue cultureregeneration of all functions of human skin in mice.
This technique can be developed two kinds of products: one is the model of human skin(screening fordrug development, cosmetics and skin toxicity
, two is the clinical products.
For clinical products, we want to make our products develop into cells is better than all other products at present, mainly used for clinical productsthe following diseases: chronic skin sores, scar free wound recovery, burn,hair regeneration clinical products. Our goal is our products through clinical trials and can be approved to enter clinical to cure patients.
We have a good grasp of the characteristics of cells and cells from culturedand maintained in culture stem cell; mouse model of human skin with mature follicles can be reused. We in this mouse model with the cultured cells used for wound treatment and showed no scar healing. In this mousemodel can grow and can be accepted by people and beautiful hair. (they translated the site from chinese with google trad apparently, but the human hair they grew on the mouse are quite good, and they are cycling!)
Ji'nan Pan Sheng direction the main techniques of biological technology limited company is the organization of pluripotent stem cell isolation and culture, induced differentiation of human skin tissue organ regenerationmodel and its application, at present, in the stem cell of human skin tissue engineering has made innovative breakthroughs, the regeneration of the skin contains the epidermis and dermis, hair follicles, sweat glands,sebaceous glands, nerve, and the existing technology can only simple regeneration of epidermis and dermis. Has the international leading level of this technology.
The company based on the field of regenerative medicine, and strive to 5 years to build the company biotechnology firm with international influence.Short term goal: 2013 to complete the registration, the application for a patent for invention 1, completed the "identification of scientific and technological achievements stem cell regeneration of human skin tissue",formulate and improve marketing planning and product samples. To complete the "experimental animal use certificate" and "experimental animalproduction license.". 2014 completed the SFDA declaration and "human skin tissue model" marketing, to complete an application for a patent for invention a, MWV cooperation with the United States, representing our"human skin tissue model" in the United States for the application,application and built Municipal Engineering Technology Research Center,and actively apply for GLP, GMP certification. In 2015 the establishment of new cooperation company, declared the FDA, investment in R & D cell differentiation inducing agents and enzyme products, company diversified development. "
I found hhis company as he filed this patent in Feb 2015 : Preparation of a tissue-engineered skin with the dermal cells
and the last update of the website text is april2015
their protocol can grow cosmetically hair, though the problem are maybe still expansion and keep inductive potential, to make hundreds of these hair by replicate the protocol. We saw progress and those two problems can be solved with differents things/ways, but still really expensive i think and hard and time consuming
the all in one protocol has to become cheap and easy to be commercializable
but this taking place in china, maybe we could be not aware of promising things there. Maybe Pantheon could be already in contact with a company to build a hair regeneration treatment using a combination of Wu Xunwei protocol + a technique to keep cells inductive potential during expansion in a cheap way ( 3D scaffolds, environment culture, or whatever , etc..)
like this recent technique for exemple from chinese scientists as well:
jun 2015
Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system.
The 3D air-liquid culture system for reproducibly generating hair follicles from dissociated epithelial and dermal papilla (DP) cells combined with a collagen-chitosan scaffold is described in this study. Wnt-CM was prepared from the supernatant of Wnt1a-expressing bone marrow mesenchymal stem cells (BM-MSCs) that maintain the hair-inducing gene expression of DP cells. The collagen-chitosan scaffold cells (CCS cells) were constructed using a two-step method by inoculating the Wnt-CM-treated DP cells and epidermal (EP) cells into the CCS.
The results demonstrate that Wnt-CM can maintain the hair induction ability of DP cells in expansion cultures, and this approach can be used for large-scale preparation of CCS cells in vitro to treat hair loss
let's contact pantheon company , see if they answer something
In Dr. Wu Xunwei's leadership, the Biological Technology Co., Ltd. has been dedicated to the skin team for many years l we Ji'nan pan, and achieved a major breakthrough, our main goal is to develop cell techniquefor the treatment of sores, bald and the establishment of human skin testplatform model. We have developed a human hair cells from tissue cultureregeneration of all functions of human skin in mice.
This technique can be developed two kinds of products: one is the model of human skin(screening fordrug development, cosmetics and skin toxicity
, two is the clinical products. For clinical products, we want to make our products develop into cells is better than all other products at present, mainly used for clinical productsthe following diseases: chronic skin sores, scar free wound recovery, burn,hair regeneration clinical products. Our goal is our products through clinical trials and can be approved to enter clinical to cure patients.
We have a good grasp of the characteristics of cells and cells from culturedand maintained in culture stem cell; mouse model of human skin with mature follicles can be reused. We in this mouse model with the cultured cells used for wound treatment and showed no scar healing. In this mousemodel can grow and can be accepted by people and beautiful hair. (they translated the site from chinese with google trad apparently, but the human hair they grew on the mouse are quite good, and they are cycling!)
Ji'nan Pan Sheng direction the main techniques of biological technology limited company is the organization of pluripotent stem cell isolation and culture, induced differentiation of human skin tissue organ regenerationmodel and its application, at present, in the stem cell of human skin tissue engineering has made innovative breakthroughs, the regeneration of the skin contains the epidermis and dermis, hair follicles, sweat glands,sebaceous glands, nerve, and the existing technology can only simple regeneration of epidermis and dermis. Has the international leading level of this technology.
The company based on the field of regenerative medicine, and strive to 5 years to build the company biotechnology firm with international influence.Short term goal: 2013 to complete the registration, the application for a patent for invention 1, completed the "identification of scientific and technological achievements stem cell regeneration of human skin tissue",formulate and improve marketing planning and product samples. To complete the "experimental animal use certificate" and "experimental animalproduction license.". 2014 completed the SFDA declaration and "human skin tissue model" marketing, to complete an application for a patent for invention a, MWV cooperation with the United States, representing our"human skin tissue model" in the United States for the application,application and built Municipal Engineering Technology Research Center,and actively apply for GLP, GMP certification. In 2015 the establishment of new cooperation company, declared the FDA, investment in R & D cell differentiation inducing agents and enzyme products, company diversified development. "
I found hhis company as he filed this patent in Feb 2015 : Preparation of a tissue-engineered skin with the dermal cells
and the last update of the website text is april2015
their protocol can grow cosmetically hair, though the problem are maybe still expansion and keep inductive potential, to make hundreds of these hair by replicate the protocol. We saw progress and those two problems can be solved with differents things/ways, but still really expensive i think and hard and time consuming
the all in one protocol has to become cheap and easy to be commercializable
but this taking place in china, maybe we could be not aware of promising things there. Maybe Pantheon could be already in contact with a company to build a hair regeneration treatment using a combination of Wu Xunwei protocol + a technique to keep cells inductive potential during expansion in a cheap way ( 3D scaffolds, environment culture, or whatever , etc..)
like this recent technique for exemple from chinese scientists as well:
jun 2015
Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system.
The 3D air-liquid culture system for reproducibly generating hair follicles from dissociated epithelial and dermal papilla (DP) cells combined with a collagen-chitosan scaffold is described in this study. Wnt-CM was prepared from the supernatant of Wnt1a-expressing bone marrow mesenchymal stem cells (BM-MSCs) that maintain the hair-inducing gene expression of DP cells. The collagen-chitosan scaffold cells (CCS cells) were constructed using a two-step method by inoculating the Wnt-CM-treated DP cells and epidermal (EP) cells into the CCS.
The results demonstrate that Wnt-CM can maintain the hair induction ability of DP cells in expansion cultures, and this approach can be used for large-scale preparation of CCS cells in vitro to treat hair loss
let's contact pantheon company , see if they answer something
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