Dr Claire Higgins video ( new from three weeks ago)

[Seuxin]

I Need this DERMAROLLER !

Maybe we could buy it already?

[mikes23]

@ swooping I thought the chinese solved the DP inductivity problem by adding an extra protein or something like that. I think Desmond posted it a while back.

[nameless]

@ swooping I thought the chinese solved the DP inductivity problem by adding an extra protein or something like that. I think Desmond posted it a while back.

I don't think so.

They can work around the DP cell problem by using iPS cells, but as far as I know nobody has found a way to culture a lot of scalp DP cells without losing hair inductivity.

[Renee]

Most of her work has been done with dr. christiano & dr. jahoda. It's been more than 2 years since their ground breaking discovery. They have been absolutely radio silent since then on this topic, I would hope in two years time they have solved the dp issue.

[hellouser]

Most of her work has been done with dr. christiano & dr. jahoda. It's been more than 2 years since their ground breaking discovery. They have been absolutely radio silent since then on this topic, I would hope in two years time they have solved the dp issue.

It was 'in two years time' two years ago...

[JayM]

Hellouser, haven't you been in contact with these guys before? I think if anyone is going to get a reply via email it will be you. I try but I don't think I come across as knowledgeable enough.

[mikes23]

https://www.baldtruthtalk.com/threads/17026-China-We-have-maintained-DP-hair-inductive-characteristics-using-eCTGF-in-culture

This is the thread I'm talking about.

[englishman]

are Dr.Heggins results positive? Do they mean anything? No offense i dont understand any of this scientific talk:/

[Swooping]

https://www.baldtruthtalk.com/thread...TGF-in-culture

This is the thread I'm talking about.

I didn't read the paper yet but watch what desmond says in that topic

Great question. So, I read the paper in detail last night and it is definitely not on the same level as Jahoda's or Lauster's work! They were simply testing one of Dr Lindner's ideas from back in 2011 to see if it's true. I was actually surprised to find Dr Lindner's papers and patents referenced all over this paper!

They simply tested CTGF to see if it improves hair-inductivity and it did. They never conducted Dr Jahoda's full gene-expression comparison study, which is really disappointing.

So to answer your question: A total gene analysis comparison was NOT conducted (only gene expression of specific markers were investigated), the DP cells cultured were NOT implanted in a foreskin or other assays to see their hair-inducing potential and they were not even cultured as well as Jahoda or Lauster's team! They simply dumped it in a well (3D) and added a whole bunch of chemicals to reduce adhesiveness. Jahoda & Lausters methods are far more delicate with DP cells.

[Swooping]

I have read the full paper and they havenīt fixed the problem at all. Desmond is right. Would be interesting to know how close some are now though. A logical consequence of an altered DP niche is the lack of CD34 and CD200 progenitors. Someone who will fix the DP problem will be a legend!

The hair follicle bulb: The dermal papilla (green cells at the center of the hair bulb) serves as both a physical and chemical niche that regulates the activity of adjacent epithelial progenitor cells (unlabelled except for a red nuclear stain) that produce the hair shaft and its surrounding inner root sheath.

[baldybald]

I have read the full paper and they havenīt fixed the problem at all. Desmond is right. Would be interesting to know how close some are now though. A logical consequence of an altered DP niche is the lack of CD34 and CD200 progenitors. Someone who will fix the DP problem will be a legend!

Cotsaralis may do it. I trust this guy a lot because he knows about hair loss mechanism a lot

[mikes23]

@ swooping my bad I remember seeing him post it last year and I thought he was saying we have solved the issue.

[nameless]

They will probably figure out how to protect hair inductivity while culturing scalp dp cells soon but I think research is going to do an end-around the problem by focusing on iPS cells instead.

[joachim]

Cotsaralis may do it. I trust this guy a lot because he knows about hair loss mechanism a lot

cotsarelis is not even trying to multiply DP cells.

[baldybald]

cotsarelis is not even trying to multiply DP cells.

Yes my bad. Hope he gets the cure with whatever technique.