Follicum results vs Minoxidil, Great Promise

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  • sagat
    replied
    Originally posted by Renee
    If those results are on mice, I wouldn't get too excited. Everything seems to grow hair on mice!
    True. Even hot human breath seems to activate follicle neogenesis on mice.

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  • Renee
    replied
    If those results are on mice, I wouldn't get too excited. Everything seems to grow hair on mice!

    Leave a comment:


  • joachim
    replied
    Originally posted by JosephFT
    This is some exclusive data that Follicum has released about 6 potential compounds they studied. The compounds were compared with Minoxidil and the results are highly in the favor of Follicum. Enjoy

    http://www.folliclethought.com/?p=509
    thanks for the insights.
    but how did you manage do get that exclusive info? =)

    do you think they could give you some basic information about how the mechanism of their molecule works? was it just an accidental discovery or is there some science behind it? (e.g. modulating wnt pathway)

    i hope they can test their substances on humans asap, because we already know that almost everything grows hair on mice. i often have the feeling that growth of hair in mice is some kind of side effect or reaction of the immune system to different substances. in the end, a coat of a mice is not comparable to human hair, not to mention MPB affected hair, although many scientists still think that mice (or sometimes bald mice) are a good model for human hair. too many decades have been wasted with testing hair growth compounds on mice.
    i would be totally surprised if this follicum molecule really grows a single hair in humans.

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  • JayM
    replied
    It does look promising. And sounds like it could even begin December time this year if things go to plan.

    I never understand however with products that contain growth factors, why in the trial do they not use people on finasteride as well? I know because it can mess up the controls and would be hard to tell if someone is telling the truth how long they'd been on fin ect but atleast you will be creating the optimal conditions to treat androgenic alopecia I.e not DHT in the scalp.

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  • lacazette
    replied
    Thanks Joseph for posting!

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  • JosephFT
    replied
    The writeup states "Today Follicum is carrying out preclinical studies, in animal models and on isolated live human tissue and even at low doses FOL-S-005 showed significant stimulation of hair growth on mice." I'm not certain if these results are from mice or human tissue. My guess would be mice. I'm just presenting the information as I receive it.

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  • Swooping
    replied
    Thanks for the article.

    What is the mechanism of action though?

    Also are these results obtained from actual human subjects or mice?

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  • JosephFT
    replied
    Re Sogeking: All of that information is in the articles. Looking to start human trials early next year, compounds are based on proteins naturally found in the human body.

    allgood: Lol They are from Sweden, so I give them a break on that one.

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  • allTheGoodNamesAreTaken
    replied
    With a name like that I just hope its not a white, gooey liquid...

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  • Sogeking
    replied
    Okay I'll bite. How far are they from starting human clinical trials?
    Any possibility for pics?
    What is their next step?
    I guess they won't divulge on what the compounds are based.

    Leave a comment:


  • JosephFT
    started a topic Follicum results vs Minoxidil, Great Promise

    Follicum results vs Minoxidil, Great Promise

    This is some exclusive data that Follicum has released about 6 potential compounds they studied. The compounds were compared with Minoxidil and the results are highly in the favor of Follicum. Enjoy

    Follicle Thought is proud to present this exclusive preclinical research data courtesy of Dr. Jan Alenfall of Follicum. Jan has provided me with a personal write-up on Follicum’s lead candidate drug, FOL-S-005, as well as two research data graphs. I have added the write-up to the original Follicum post. Below are two graphs demonstrating the…
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