Maybe Replicel will actually be the cure

[hellouser]

I think it makes sense. I am a girl, so I have diffuse hair loss and I wouldn't believe that one single injection in one single spot would make the cells migrate to all bald areas.

Of course not. Also, if your a chick, you need to read into this:

https://www.baldtruthtalk.com/threads/20640-Histogen-raises-9.49-million

[champpy]

Im one of the people that wants get this done as soon as its released, even if its over seas.

The one thing that worries me about the travel though is that it will take weeks for the cells to multiply.
I def cannot afford to stay in another country for weeks, waiting for the cells to multiply then be re-injected back. The cost of the procedure and the trip (hotel for over a week) will add up fast.

Then if multiple injections/sessions are needed....whoa, that could get pricey as heck.

Do you think that it might be possible for a satellite office be set up here in the US, that way they could harvest the cells here, have them transport the cells back to Asia to be multiplied and we just make the trip once the cells are ready?

Maybe the company that preforms this procedure can set up some nearby off shore medical office that can do it there, that way they can bypass all the US laws

[sagat]

Im one of the people that wants get this done as soon as its released, even if its over seas.

The one thing that worries me about the travel though is that it will take weeks for the cells to multiply.
I def cannot afford to stay in another country for weeks, waiting for the cells to multiply then be re-injected back. The cost of the procedure and the trip (hotel for over a week) will add up fast.

Then if multiple injections/sessions are needed....whoa, that could get pricey as heck.

Do you think that it might be possible for a satellite office be set up here in the US, that way they could harvest the cells here, have them transport the cells back to Asia to be multiplied and we just make the trip once the cells are ready?

Maybe the company that preforms this procedure can set up some nearby off shore medical office that can do it there, that way they can bypass all the US laws

I could imagine the insane demand for this when it becomes available. You would probably have to go on a waiting list for 3 years.. lol

Anyway too early to be discussing the hypothetical.

[veca]

I could imagine the insane demand for this when it becomes available. You would probably have to go on a waiting list for 3 years.. lol

Anyway too early to be discussing the hypothetical.

Hahaha...you are 10000% right my friend....it's crazy what people worry about.

[FooFighter]

According to their first trial they averaged 11% increase in density with only one injection in a 6 month follow up. Hopefully more injections at a higher dose yields a higher percentage increase in density. I'm cautiously optimistic.

Their first trial was designed to proove safety not efficasy. Higher doses doesnt mean better results. In much cases higher doses mean poison for body. So next trial is designed to show which dose is best for patients.
Shiseido is not stupid for investing big money in this project.

Replicel dont use iPSCs cells. They confirmed me.

[dutchguyhanging]

i think Hollywood starts would be the first on the list. They need the treatment just to keep up with their work )

I agree Foofighter, Shiseido is not stupid enough to invest big money as well as such big claims. They are literally saying we did it and will be available in Japan in 3 years. They are active online e.g. facebook twitter, correct me if im wrong but they are also going to hairloss congress in miami. It seems all legit to me

[luiza]

i think Hollywood starts would be the first on the list. They need the treatment just to keep up with their work )

I agree Foofighter, Shiseido is not stupid enough to invest big money as well as such big claims. They are literally saying we did it and will be available in Japan in 3 years. They are active online e.g. facebook twitter, correct me if im wrong but they are also going to hairloss congress in miami. It seems all legit to me

Do you think that they can get a NW7 back to a NW1? (of course that would be much more expensive and take a long time but in theory that's what they are saying). That's also what David Hall was asked and he pretty much affirmed it is only a matter of dosage and frequency.
I think it will ruin their reputation if all those claims coming from Shiseido are not true and the results from phase II are shit.

It is hard to believe that it will be here soon though. I was expecting a full cure to be here only in 10 or 15 years, so I am still skeptical but deep inside I really wanna believe it is true, I am just trying not to, so I wouldn't get disappointed if they failed haha

[JayM]

For me I always refer back to transgender people. The INSANE hair growth they get proves to me that follicles can be regenerated.

[luiza]

For me I always refer back to transgender people. The INSANE hair growth they get proves to me that follicles can be regenerated.

Yeah, hope you are right I still have quite "a lot" of hair but I've been losing it since I was 14 and now I am 22 lol I am not losing hair anymore (or maybe I still am, but really slowly), but I can't get what I lost back I wonder if my follicles are affected by the fibrosis process. That must be the challenge they are facing..
But if they are capable of forming new follicles, as they stated, it shouldn't be a problem. Let's see.

[brocktherock]

Could you have the biopsy done in your country and have it sent to japan or would that be violating some stupid law?

[balding1983]

Yes so far Replicel ,unofficially, through emails to curious parties relayed that their RCH-01 treatment would mostly serve as immunizing solution, meaning halting hair loss. Now they are claiming the cure. I have to warn you though. Various other news sites and sources and at some time even REplicel were hyping the effectiveness of RCH-01 during the times prior to them releasing RCH Phase 1 trials. And then once the results came it was kind of a big disappointment. However even if this only immunizes and halts progression of AGA it will still be valuable as hair loss treatment. We need to wait and see. Thankfully the fast tracked trials for this in Japan should give us some answers soon enough.

As for the iPCs... Well have no idea what that is about. However the sceptic in me thinks that it is too early for making DP cells out of iPSC cells. Guess we'll see.

I am really glad someone here has a good enough memory to remember how Replicel was hyped up before those phase 1 results were released.

All of the recent articles published online including the ones quoted by Replicel on their social network portals are all from obscure blogs and online publications. If there is going to be a genuine cure for baldness it will be on the broadsheets and have decent coverage on the 24 hour news channels. In fact, I heard about the Ramotraban break through on the news not the internet (I visit BTT at least once a day lol).

Secondly, my faith in Replicel actually lessened when they made that announcement about immunising DHT sensitive follicles with their process so that they will be DHT resistant. Think about it. How will they objectively prove that the immunised follicles as being DHT resistant? Patients will have to be followed up for decades to see if their hairloss progresses over time. Have replicel done this or made plans for a longterm follow up study?

Furthermore, the study design will be complicated by the fact that there is no clear way to predict how a man's hair loss will progress with time so you can never tell whether any stopping of hair loss is due to their treatment or innate physiological/genetic factors.

[Paul73]

Yeah, hope you are right I still have quite "a lot" of hair but I've been losing it since I was 14 and now I am 22 lol I am not losing hair anymore (or maybe I still am, but really slowly), but I can't get what I lost back I wonder if my follicles are affected by the fibrosis process. That must be the challenge they are facing..
But if they are capable of forming new follicles, as they stated, it shouldn't be a problem. Let's see.

Hi Luiza!

I agree that if new follicles can me formed, then fibrosis wouldnīt be a problem. But where did you see the info that Replicel will create new follicles?

I thought they were going to inject cells only.

I donīt know if Replicel will be able to regrow hairs on areas that are bald for more than 5 -10 years.

[Renee]

I believe the more viable treatment would come from dr lauster. The key is to grow hair follicles in the lab and implant directly into scalp. His team said after their discovery in 2010 this would be a reality in 2015. I wonder what happen.

[mlamber5]

I am really glad someone here has a good enough memory to remember how Replicel was hyped up before those phase 1 results were released.

All of the recent articles published online including the ones quoted by Replicel on their social network portals are all from obscure blogs and online publications. If there is going to be a genuine cure for baldness it will be on the broadsheets and have decent coverage on the 24 hour news channels. In fact, I heard about the Ramotraban break through on the news not the internet (I visit BTT at least once a day lol).

Secondly, my faith in Replicel actually lessened when they made that announcement about immunising DHT sensitive follicles with their process so that they will be DHT resistant. Think about it. How will they objectively prove that the immunised follicles as being DHT resistant? Patients will have to be followed up for decades to see if their hairloss progresses over time. Have replicel done this or made plans for a longterm follow up study?

Furthermore, the study design will be complicated by the fact that there is no clear way to predict how a man's hair loss will progress with time so you can never tell whether any stopping of hair loss is due to their treatment or innate physiological/genetic factors.

I think Replicel was basically trying to say that by replacing the balding area dermal cup cells which are bad, with DHT resistant dermal cup cells which are located on the back/side of head, it will work to essentially kickstart the existing follicles back into working because they have the healthy "first initiator" of signals in the healthy dermal cup cells. I think the main problem with this is going to be, after the punch biopsy and multiplication, how to effectively get them to migrate to where the should be upon injecting into bald areas.

[FooFighter]

The main problem about stem cells therapies is that we dont have infrastracture, machines, enough educated people to offer this treatments to big population. Second problem is that we still dont know enough about stem cells. Just look this video

https://www.youtube.com/watch?t=164&v=hw_uOLuTiZI