World Hair Congress 2015

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  • It's2014ComeOnAlready
    Senior Member
    • Sep 2014
    • 584

    #61
    Originally posted by Pentarou
    Anything else going? Seriously, are we in a worse situation than 2014?

    The mega-treatments like Histogen were always going to be game-changing or stillborn, IMO.
    Bim is up in the air, CB is in phase 2, Replicel will be in Japan and asian markets by 2018 (they are claiming it's a full cure), Setipiprant (PGD2 blocker backed by Cotsarelis) will be entering phase 2 in Dec/Jan. SM04554 will be finishing phase 2 in September. I'm really excited for SM because of all the "breakthrough discoveries" regarding the WNT pathway and hair loss. All research seems to point to activating the WNT pathway as the best chance for regrowth. They recruited 300 participants (the max for phase 2), and only norwood 4-6. Samumed is also backed by Pfizer, and are the leading company developing drugs for activating or inhibiting the WNT pathway.

    We won't have anything this yr, but 2016 an 2017 should be very good indeed.

    Comment

    • KO1
      Senior Member
      • Jan 2012
      • 805

      #62
      Originally posted by Pentarou
      Anything else going? Seriously, are we in a worse situation than 2014?

      The mega-treatments like Histogen were always going to be game-changing or stillborn, IMO.
      I think the only interesting things are Seti, which may not be greater than fin, but it can only help. And SM04554, which is a Wnt agonist, which is implicated in HF morphogenesis and growth. But I have my doubts on the company involved with SM.

      Comment

      • It's2014ComeOnAlready
        Senior Member
        • Sep 2014
        • 584

        #63
        Originally posted by KO1
        I think the only interesting things are Seti, which may not be greater than fin, but it can only help. And SM04554, which is a Wnt agonist, which is implicated in HF morphogenesis and growth. But I have my doubts on the company involved with SM.
        Samumed has backing from pfizer, and they've been able to pay for a massive phase 2. If they claim to be the leading WNT research drug company, and pfizer backs them, then they're probably legit.

        Comment

        • Tenma
          Senior Member
          • Nov 2013
          • 172

          #64
          But I have my doubts on the company involved with SM.
          Do you think they are not legit?

          Comment

          • KO1
            Senior Member
            • Jan 2012
            • 805

            #65
            Originally posted by Tenma
            Do you think they are not legit?
            So here's the thing. This company was formed primarily to work with Wnt inhibitors in order to treat cancer, and they found their drug candidates via a screen on Pfizer's chemical library. Their whole website, plus the experience of the people involved with the company points to a firm focused on cancer. But for some bizarre reason, a company formed to use Wnt inhibitors to treat cancer is now using Wnt promoters to treat MPB despite none of the scientists having a research interest in MPB?

            Strikes me as odd.

            Comment

            • It's2014ComeOnAlready
              Senior Member
              • Sep 2014
              • 584

              #66
              Originally posted by KO1
              So here's the thing. This company was formed primarily to work with Wnt inhibitors in order to treat cancer, and they found their drug candidates via a screen on Pfizer's chemical library. Their whole website, plus the experience of the people involved with the company points to a firm focused on cancer. But for some bizarre reason, a company formed to use Wnt inhibitors to treat cancer is now using Wnt promoters to treat MPB despite none of the scientists having a research interest in MPB?

              Strikes me as odd.
              dble post. deleted

              Comment

              • It's2014ComeOnAlready
                Senior Member
                • Sep 2014
                • 584

                #67
                Originally posted by KO1
                So here's the thing. This company was formed primarily to work with Wnt inhibitors in order to treat cancer, and they found their drug candidates via a screen on Pfizer's chemical library. Their whole website, plus the experience of the people involved with the company points to a firm focused on cancer. But for some bizarre reason, a company formed to use Wnt inhibitors to treat cancer is now using Wnt promoters to treat MPB despite none of the scientists having a research interest in MPB?

                Strikes me as odd.
                Well, they have drugs in trials for osteoarthritis, hair loss, and different forms of cancer. Their main focus is the WNT pathway, and in terms of regenerative medicine, all of these issues fall under this umbrella. Kythera, for instance, is interested mostly in medical aesthetics, and their only other drug is one that reduces double-chin fat.

                I'd rather there be a company whose expertise was WNT regarding hair loss, rather than a company whose expertise was hair loss, trying to tinker with the WNT pathway.

                Comment

                • Desmond84
                  Senior Member
                  • Oct 2012
                  • 987

                  #68
                  Whoaaaa guys! They've just released the first draft of abstracts being presented at the congress. Dr Takashi Tsuji is presenting a talk called: "Hair Regeneration as a Future Organ Replacement Regenerative Therapy" on Friday November 20th.

                  Another interesting piece of information I found was that Dr Takashi Tsuji also works for RIKEN Centre for Developmental Biology in the Department of Organ Regeneration! Here's the link:



                  This centre is actively working to regenerate hair follicles. Let's see if he has anything new to present at this congress <fingers crossed>

                  Comment

                  • Arieux
                    Member
                    • Jun 2015
                    • 81

                    #69
                    @Desmond - that's a good news! Tsuji about 2011 expected about the hair regeneration:
                    that it will take five to 10 years to bring the technology to market.
                    (http://www.tus.ac.jp/en/initatives/vol02/). We have 2016 soon, so it's high time to present something concrete!

                    Comment

                    • lacazette
                      Senior Member
                      • May 2015
                      • 394

                      #70
                      Great new Desmond. And with the japan timeline approval, it could go more quickly than we thought!!

                      Comment

                      • ar50
                        Senior Member
                        • May 2013
                        • 115

                        #71
                        Originally posted by Desmond84
                        Whoaaaa guys! They've just released the first draft of abstracts being presented at the congress. Dr Takashi Tsuji is presenting a talk called: "Hair Regeneration as a Future Organ Replacement Regenerative Therapy" on Friday November 20th.

                        Another interesting piece of information I found was that Dr Takashi Tsuji also works for RIKEN Centre for Developmental Biology in the Department of Organ Regeneration! Here's the link:



                        This centre is actively working to regenerate hair follicles. Let's see if he has anything new to present at this congress <fingers crossed>
                        Whoah thats indeed good news and today I just made an appointment for FUE. Is this method going to make hair transplants obsolete?

                        Comment

                        • nameless
                          Senior Member
                          • Feb 2013
                          • 965

                          #72
                          Originally posted by Desmond84
                          Whoaaaa guys! They've just released the first draft of abstracts being presented at the congress. Dr Takashi Tsuji is presenting a talk called: "Hair Regeneration as a Future Organ Replacement Regenerative Therapy" on Friday November 20th.

                          Another interesting piece of information I found was that Dr Takashi Tsuji also works for RIKEN Centre for Developmental Biology in the Department of Organ Regeneration! Here's the link:



                          This centre is actively working to regenerate hair follicles. Let's see if he has anything new to present at this congress <fingers crossed>

                          "......as a Future Organ Replacement Regenerative Therapy"

                          this is down the road. Probably (you guessed it) 5 years.

                          Comment

                          • macbeth81
                            Senior Member
                            • Sep 2014
                            • 101

                            #73
                            The Science ZERO Japan video @ 4:10 states Dr. Tsuji is aiming for practical use within 10 years. We can not even get five years anymore, now we have transitioned into decades away.

                            Comment

                            • HairlossAt15
                              Member
                              • May 2013
                              • 91

                              #74
                              Good to see that Kythera is a sponsor of the event

                              Comment

                              • FooFighter
                                Member
                                • Feb 2015
                                • 90

                                #75
                                Originally posted by macbeth81
                                The Science ZERO Japan video @ 4:10 states Dr. Tsuji is aiming for practical use within 10 years. We can not even get five years anymore, now we have transitioned into decades away.

                                https://www.youtube.com/watch?v=-p0Hvrx093I
                                I think nobody can creat hair follicle from stem cells still. They can create only body hair which is different.

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