Where are the phase IIb results for Bimatoprost?
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Im worried about bim for one reason. It is a hair growth stimulant. If it works shouldnt it work to regrow hair, with or without seti? I mean i understand that these two may work better in conjunction we each other but if you are already maintaining with fin or dut, you wouldnt need seti, so why wouldnt bim alone be of some help?
Minox is sold as a growth stimulant . We use fin to help maintain that growth.
why is it bims release is dependant on seti? Sad to say but it leads me to think that bim alone is not that great afterall
Hopefully someone can set me straight on thisComment
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Im worried about bim for one reason. It is a hair growth stimulant. If it works shouldnt it work to regrow hair, with or without seti? I mean i understand that these two may work better in conjunction we each other but if you are already maintaining with fin or dut, you wouldnt need seti, so why wouldnt bim alone be of some help?
Minox is sold as a growth stimulant . We use fin to help maintain that growth.
why is it bims release is dependant on seti? Sad to say but it leads me to think that bim alone is not that great afterall
Hopefully someone can set me straight on this
This is just speculation from one article I read, so this analogy may or may not apply until they are tested.Comment
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I really hope this SCALP treatment they may have will do something. I for one tried the 0.03% for about 4 months and I cant really see any growth at all. Nothing significant at all, which sucked. Thought I would at lease get a few new hairs, id even settle for some vellus.
But alas , nothing.Comment
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You guys are going to think I'm nuts, but I'm starting to wonder if Allergan is going to announce bim August 6th at their Q2 earnings conference call.
I say this because poster, "bornthisway" says that he heard from a dermatologists office that claims to work closely with Allergan says they plan on releasing a hair loss product based on bimatoprost as early as this summer. BiqqieSmalls is a shareholder of Allergan stock, and he spoke with Investor Relations back in May, and they said, they haven't released results, even to shareholders. The then asked then when, and they responded "in a few months." When he asked what was taking so long, they said it was because of the "complexity of bimatoprost."
I think it's possible that we might either see results, or some sort of announcement. I think they've been holding back because a) people will be trying to get their hands on it before the release b) the acquisition of Kythera and setipiprant. There is a lot going on behind the scenes, and since Allergan seems very determined to dominate medical aesthetics, they are going to want to cover the entire hair loss market by having the new minoxidil and propecia, but only more effective, and without the sides.
Keep a look out. I think it's possible.Comment
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I'd mention what I believe is going on, but I don't feel like getting into a debate. Please see my other posts in this thread regarding phase 3.
If you don't think it's at all possible, I'm calling BS, because they'd be at a serious disadvantage by posting that they are in a phase 3 trial, while the drug is already in the market. There's also the issue of people wanting to get their hands on this drug before it reaches the market, and they had the same problem with latisse earlier on.Comment
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According to clinicaltrials.gov they finished the study in November 2014 and should have the final results in January 2015: https://clinicaltrials.gov/ct2/show/NCT01904721 It's May 2015 now, shouldn't they have already published the results? Or do pharma companies keep the data for themselves? Would like to know what
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I'd quite like to hear why you think it will be able to miss phase 3. Like not to argue just because it's interesting! And to be fair I've only heard of Bim from my Grandad because his eyes are messed up haha! I understand that bim is currently used in eye drops ect and for lattisse but has there ever been drugs allowed to skip phase 3 for a different use kind of thing?
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I'd quite like to hear why you think it will be able to miss phase 3. Like not to argue just because it's interesting! And to be fair I've only heard of Bim from my Grandad because his eyes are messed up haha! I understand that bim is currently used in eye drops ect and for lattisse but has there ever been drugs allowed to skip phase 3 for a different use kind of thing?
I've done a lot of digging - reading articles, watching interviews etc. It seems to me that a very likely scenario is that they've continued on with trials. However, the trial hasn't been posted to clinicaltrials.gov with very good reason.
Firstly, this drug already exists in the market, and according to former Allergan CEO David Pyott, many people were trying to get their hands on latisse before it got to market. In this case, it would be worse because other companies can make the drug, and if you wanted, you could buy pure bimatoprost powder off a website like alibaba.com and make it yourself. This would hurt their profits and their customers. The drug has not passed trials yet, and the FDA wouldn't want an outrageous situation where a popular hair loss treatment would get in the hands of the public in a unsafe and unregulated fashion, because this would undoubtedly happen if word got out.
Secondly, they set up their phase 2 trials with enough participants so that if they saw positive results, they could immediately jump into a phase 3. Therefore, posting to clinicaltrials.gov as a recruitment tool wouldn't be necessary.
So, I think they could have quietly progressed, and in accordance with the FDA, have omitted their trial to be posted on clinicaltrials.gov, for the reasons I have posted. It's unusual, complex, but I think it makes more sense then them slowing down the program by a year, if it was successful. There's no reason to do that.
I also think the acquisition of Kythera and Setipiprant is good reason to believe bimatoprost worked. With that move, it proves they want to dominate the medical aesthetics market. Not only that, but they are mutually reliant on prostaglandin science, which is why they are as positive about Setipiprant as they are. About 10% of men do something about their hair loss. With a side effect-free drug like setipiprant, and a drug that will regrow anywhere on the scalp, that number would jump to near 100%. Which means $$$$$$$$$$$$. No man wants to be bald.Comment
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