Where are the phase IIb results for Bimatoprost?

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  • BiqqieSmalls
    Senior Member
    • Feb 2015
    • 135

    They're definitely trying to capture the whole MPB market share and they will succeed. I am super stoked.

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    • burtandernie
      Senior Member
      • Nov 2012
      • 1563

      I think everyone is curious what using those 2 drugs in combination would do. What kind of results are we talking? Could be minor or huge really impossible to guess. It would be kind of funny to see MPB nearly cured with a combo like this that no one would ever predicted or expected. For all the talk everyone does about millions of things about diet, air pollution, and so on causing MPB it would be odd for something like this to grow back a lot of hair. I guess lots of people turning out to be wrong is not a new thing either.

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      • FearTheLoss
        Senior Member
        • Dec 2012
        • 1581

        Originally posted by burtandernie
        I think everyone is curious what using those 2 drugs in combination would do. What kind of results are we talking? Could be minor or huge really impossible to guess. It would be kind of funny to see MPB nearly cured with a combo like this that no one would ever predicted or expected. For all the talk everyone does about millions of things about diet, air pollution, and so on causing MPB it would be odd for something like this to grow back a lot of hair. I guess lots of people turning out to be wrong is not a new thing either.
        That's not true at all, numerous hair loss researchers have stated a combo like this should give great results. PGE2 up and PGD2 down = hair

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        • Justinian
          Senior Member
          • Sep 2014
          • 148

          Originally posted by It's2014ComeOnAlready
          " The true Holy Grail may come from combining a drug like Latisse with a certain type of medication commonly used to treat allergies and asthma. The medication blocks a hormone-like substance that prevents hair from growing. A treatment like this might help with hair growth. Using these drugs in combination is like taking your foot off-break and stepping on gas at the same time."
          Very good find. It's very interesting how he mentioned this way back in early 2014.

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          • BiqqieSmalls
            Senior Member
            • Feb 2015
            • 135

            So I guess the Investor Relations woman was right. Why else would Allergan buy $KYTH if they didn't want to use Seti in conjunction with Bim? To whomever said Bim's Phase II had negative results... what now?!

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            • rdawg
              Senior Member
              • Jun 2012
              • 996

              Originally posted by It's2014ComeOnAlready
              Allergan is buying Kythera for $2.1 billion. I find this very interesting, given that Kythera's Chief Medical Officer worked at Allergan for over a decade. Also, they announced trials for Setipiprant soon after the phase IIb studies for bimatoprost were complete for Allergan. I'm sure they knew the results, given the company ties. This is very interesting given the mutual reliance on prostaglandin science.

              It looks like Allergan may be trying to corner the hair loss market. Look at this quote in April 2014 from Bosley Medical Director, Ken Washenik:

              " The true Holy Grail may come from combining a drug like Latisse with a certain type of medication commonly used to treat allergies and asthma. The medication blocks a hormone-like substance that prevents hair from growing. A treatment like this might help with hair growth. Using these drugs in combination is like taking your foot off-break and stepping on gas at the same time."

              Looks like Allergan is trying to corner the hair loss market. Sure, nobody wants a double chin either, but if Setipiprant is successful, it would shatter any earnings made by that injectable fat-burning drug. I really hope this means bim was successful, it may mean just that.
              This could come down to the patent thing as well, multiple companies can make the bimatoprost solution can't they?

              but they can't make a combination of these two.

              something big may be brewing behind the scenes here, and neither of these products are too far in the distance.

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              • throwaway184
                Junior Member
                • Jun 2015
                • 5

                close enough that I can get by w/o trying Fin?

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                • 79BirdofPrey
                  Member
                  • Jul 2010
                  • 67

                  New to this topic - what is the working principle behind Bimatoprost? Is it another DHT blocker?

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                  • Ziggyz123
                    Senior Member
                    • Feb 2015
                    • 367

                    Originally posted by throwaway184
                    close enough that I can get by w/o trying Fin?
                    It is still years away.

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                    • GSD
                      Member
                      • Apr 2015
                      • 75

                      Originally posted by 79BirdofPrey
                      New to this topic - what is the working principle behind Bimatoprost? Is it another DHT blocker?


                      NO, its a better minoxidil

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                      • lacazette
                        Senior Member
                        • May 2015
                        • 394

                        Do the "21 century cure" bill could speed up allergan clinical trials? Speed the timeline for commercial use?

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                        • Hemo
                          Senior Member
                          • Apr 2015
                          • 138

                          Originally posted by BiqqieSmalls
                          So I guess the Investor Relations woman was right. Why else would Allergan buy $KYTH if they didn't want to use Seti in conjunction with Bim? To whomever said Bim's Phase II had negative results... what now?!
                          Or they really wanted the double chin treatment...
                          Not saying Allergan isn't interested in Seti, but it's not Kythera's only product.

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                          • It's2014ComeOnAlready
                            Senior Member
                            • Sep 2014
                            • 584

                            Originally posted by lacazette
                            Do the "21 century cure" bill could speed up allergan clinical trials? Speed the timeline for commercial use?
                            Hopefully, and likely. There is a provision in the bill that speeds up development for repurposed drugs. AND guess what? The majority of Congress (of both dems and repubs) just cosponsored the bill, meaning it will surely make it through Congress.

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                            • lacazette
                              Senior Member
                              • May 2015
                              • 394

                              Originally posted by It's2014ComeOnAlready
                              Hopefully, and likely. There is a provision in the bill that speeds up development for repurposed drugs. AND guess what? The majority of Congress (of both dems and repubs) just cosponsored the bill, meaning it will surely make it through Congress.

                              http://energycommerce.house.gov/pres...igns-cures2015
                              Omg that's great! New generation treatments are really not far away from us. Everything goes in the good way ( 21st century cure, competition between companies,etc..). Even the more pessimists guys begin to change their mind I'm sure . Nothing compared like a few years ago with all these 'breaktrough mice studies' haha

                              Comment

                              • Hemo
                                Senior Member
                                • Apr 2015
                                • 138

                                Originally posted by lacazette
                                Omg that's great! New generation treatments are really not far away from us. Everything goes in the good way ( 21st century cure, competition between companies,etc..). Even the more pessimists guys begin to change their mind I'm sure . Nothing compared like a few years ago with all these 'breaktrough mice studies' haha
                                What makes you say they're not far away? Something has to actually work before the legislation makes any difference. There's very little proof that any of the treatments people are excited for actually do anything.

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