Did you do that? I thinks its worth a shot or maybe somebody could call in the next show and just ask.
This thread becomes so disturbing to read. It would be a shame if this stuff would not work, but even a bigger shame if we keep talking about it if it does not.
Where are the phase IIb results for Bimatoprost?
Collapse
X
-
https://clinicaltrials.gov/ct2/show/NCT01904721
This study has been completed.
What's your next move?
I wonder why are always the same people in every thread...Leave a comment:
-
https://clinicaltrials.gov/ct2/show/NCT01904721
This study has been completed.
What's your next move?
My next move... is this thread about you? I'm not up against anyone, maybe you think you're my opponent or something haha. I've shown in the thread many times that this drug works very well. My enthusiasm comes from that. They could be in phase 3 right now for all we know. They don't have to post anything to clinicaltrials.gov yet because their patients were already enough patients enrolled from previous studies. We don't know what the status is! I hope they are continuing, we'll just have to wait and see.Leave a comment:
-
Even more positive, it seems the higher the dose the better response, and they've found the best % with the lowest amount of sides.
What would hold them back from pushing this forward, the only thing I can think of is that the results were good, but not amazing(lets say, 5-10% better than minoxidil) and they just aren't willing to put out a product unless it's a significant improvement. Hopefully that's not the case.Leave a comment:
-
Like I've stated earlier, phase 2b success has the implication of a phase 3 and a launch. It would pretty much be letting the cat out of the bag. Being quiet, while continuing the study (it says "this study is ongoing but not recruiting participants" on clinicaltrials.gov) ensures that when it is time to announce success, you actually HAVE a product to market. It makes no sense to announce results now, the stock is doing fine on its own. Yes, normally good news is released at the time it occurs, but given what's happened with this company recently, it actually makes sense to hold back.
As the saying goes: "no news is good news."
This study has been completed.
What's your next move?Leave a comment:
-
Yeah, here's a quote from their patent, filed in feb 14, published in Oct 14: "The preferred bimatoprost concentration range is about 2-4% w/w, more preferably about 2.5-3.5% w/w. These preferred bimatoprost concentration ranges allow a surprisingly good balance to be achieved between the wanted pharmacologic effects of the composition and any unwanted side-effects. It had previously been thought that bimatoprost compositions for stimulating growth of hair should have a much lower bimatoprost concentration; this has now surprisingly been found not to be the case."
What would hold them back from pushing this forward, the only thing I can think of is that the results were good, but not amazing(lets say, 5-10% better than minoxidil) and they just aren't willing to put out a product unless it's a significant improvement. Hopefully that's not the case.Leave a comment:
-
Yeah, here's a quote from their patent, filed in feb 14, published in Oct 14: "The preferred bimatoprost concentration range is about 2-4% w/w, more preferably about 2.5-3.5% w/w. These preferred bimatoprost concentration ranges allow a surprisingly good balance to be achieved between the wanted pharmacologic effects of the composition and any unwanted side-effects. It had previously been thought that bimatoprost compositions for stimulating growth of hair should have a much lower bimatoprost concentration; this has now surprisingly been found not to be the case."Leave a comment:
-
double-blind, placebo-controlled pilot study of
16 men with androgenetic alopecia, applying
topical latanoprost 0.1% daily on the right or left
frontotemporal mini-zones. After 24 weeks of treatment,
the latanoprost-treated site demonstrated a
significant increase in hair density compared with
baseline (P \ .001) and placebo site (P = .0004). Besides a localized erythematous reaction, no
adverse events were reported. Despite these
findings, in a case report of a woman with female
pattern hair loss treated with injected bimatoprost, a
similar response was not seen.24"
i'd say that's pretty encouraging. positive response and no adverse affects at 0.1% solution, Isn't bim using a 1-3% solution?Leave a comment:
-
-
Leave a comment:
-
Well I just read this the other day: http://www.nytimes.com/2015/04/16/fa...for-women.html
"Dr. Piliang said she expects Latisse’s results to be less striking on the head than on the lashes because the drug works by shifting more hair from the resting phase to the growing phase. For lashes, only about 30 percent of the hair is in the growing phase at any given time, she said, but on the scalp, that figure is 80 or 90 percent."
The 2a results aren't impressive and they tested 3 different doses (all very small, but they don't list the exact ones), so we'll have to wait and see how much the dose actually matters when increased greatly.Leave a comment:
-
haha I'm not sure you know what the phrase "blindly optimistic" means. I've based my enthusiasm solely on facts. By those facts, I have a right to be optimistic. Please provide valid arguments, and correct usage of phrasing.Leave a comment:
-
I'm not gonna keep going about this, but they selected 300 men and 300 women for phase 2 so that if results were positive, they could immediately jump into phase 3. The number of recruited people is there, and they've already designed the trial (why would phase 3 protocol be any different from phase 2?). Data collection took from Nov to Jan.
Please tell me, since you believe timeline isn't the issue here, what are the reasons to doubt? I find it hard to doubt at all, given everything I've read.
You're blindly optimistic.Leave a comment:
-
Well I just read this the other day: http://www.nytimes.com/2015/04/16/fa...for-women.html
"Dr. Piliang said she expects Latisse’s results to be less striking on the head than on the lashes because the drug works by shifting more hair from the resting phase to the growing phase. For lashes, only about 30 percent of the hair is in the growing phase at any given time, she said, but on the scalp, that figure is 80 or 90 percent."
The 2a results aren't impressive and they tested 3 different doses (all very small, but they don't list the exact ones), so we'll have to wait and see how much the dose actually matters when increased greatly.Leave a comment:
Leave a comment: