Kythera Acquires Rights to PGD2 Blocking Setipriprant for New Hair Loss Treatment

[Hairismylife]

You've been on here 5 years. wow. that is nothing. Your logic is flawed. Just because nothing has happened in those 5 years doesn't mean it won't. People were saint the same thing as you in the 90s, and then boom, propecia came out. it is effective, but not perfect. the next drug will also be effective, and maybe a bit more perfect. They have learned a lot about mpb in the last 5, and are now applying that knowledge. There are about 6 new treatments for AGA in the pipeline, as opposed to basically none 5 years ago. Intercytex and aderans failed because the science was not there yet, and their failure is a step along the way to a really huge stem cell fix that is still a bit off. I think you're quite wrong about not having anything else in five years though. Things do happen, just not according to our personal plans. They cured hepatitis C out of nowhere, as well as alopecia areata. You never know when something will work, and some things in trials now have a lot of promise. Your speculation that nothing is coming is no more accurate than saying "5 years". There is pretty much zero chance that nothing else will come in the next 20 years, that is just nonsense. I'm already using Adenogen from shiseido and it has equal efficacy to minox with no sides, so you're already wrong that there is nothing new. I would say that as soon as 3 years we could have a new maintenance treatment, and within 20 there will definitely be cell based therapies. If you educated yourself on the science, that becomes very clear.

How much regrowth from Adenogen?

[sdsurfin]

You've been on here 5 years. wow. that is nothing. Your logic is flawed. Just because nothing has happened in those 5 years doesn't mean it won't. People were saint the same thing as you in the 90s, and then boom, propecia came out. it is effective, but not perfect. the next drug will also be effective, and maybe a bit more perfect. They have learned a lot about mpb in the last 5, and are now applying that knowledge. There are about 6 new treatments for AGA in the pipeline, as opposed to basically none 5 years ago. Intercytex and aderans failed because the science was not there yet, and their failure is a step along the way to a really huge stem cell fix that is still a bit off. I think you're quite wrong about not having anything else in five years though. Things do happen, just not according to our personal plans. They cured hepatitis C out of nowhere, as well as alopecia areata. You never know when something will work, and some things in trials now have a lot of promise. Your speculation that nothing is coming is no more accurate than saying "5 years". There is pretty much zero chance that nothing else will come in the next 20 years, that is just nonsense. I'm already using Adenogen from shiseido and it has equal efficacy to minox with no sides, so you're already wrong that there is nothing new. I would say that as soon as 3 years we could have a new maintenance treatment, and within 20 there will definitely be cell based therapies. If you educated yourself on the science, that becomes very clear.

[LongWayHome]

It's true, nothing ever comes out. Everything is always 5 years away.

I will graduate college, get a master's degree, get a PhD, have a wife, kids, and the kids will grow up and have kids. And still, i'll come back to TBT 2-3 times a year and read about the next big treatment that is finally coming after Propecia/Rogaine. Which will be a drug that works like finasteride with no side effects...lol. Meanwhile, all the mice in the world are growing hair by just mixing water with Kool-aid powder and adding some chopped up onions in it. Because you know, everything grows hair on mice.

OMG man that was good! I actually laughed.
"...All the mice in the world are growing hair by just mixing water with Kool-aid powder..."
That's gold jerry! Gold!

Sad, but true.

[PatientlyWaiting]

lol... Most treatments with scientififc background is five-forever treatments... so i guess its another bullshit..

i have been following this forum since 2009 - MORE THAN FIVE YEARS.. and no five-years treatment has ever came to market.
only Propecia and Minoxidil getting new designs.. lol

It's true, nothing ever comes out. Everything is always 5 years away.

I will graduate college, get a master's degree, get a PhD, have a wife, kids, and the kids will grow up and have kids. And still, i'll come back to TBT 2-3 times a year and read about the next big treatment that is finally coming after Propecia/Rogaine. Which will be a drug that works like finasteride with no side effects...lol. Meanwhile, all the mice in the world are growing hair by just mixing water with Kool-aid powder and adding some chopped up onions in it. Because you know, everything grows hair on mice.

[Scientalk56]

Do you think science is bullshit then? ... lol

No, its just 20 years far..in best case scenario.. those are great news for my grandchildren.

We need "finally a treatment got a fda apporval for treating baldness" news.. which we wont see..

Back to minixidil and propecia..

[walrus]

lol... Most treatments with scientififc background is five-forever treatments... so i guess its another bullshit..

i have been following this forum since 2009 - MORE THAN FIVE YEARS.. and no five-years treatment has ever came to market.
only Propecia and Minoxidil getting new designs.. lol

Do you think science is bullshit then? ... lol

[Scientalk56]

lol... Most treatments with scientififc background is five-forever treatments... so i guess its another bullshit..

i have been following this forum since 2009 - MORE THAN FIVE YEARS.. and no five-years treatment has ever came to market.
only Propecia and Minoxidil getting new designs.. lol

[NeedHairASAP]

whats so special about " Kythera"? is that another five-forever years treatment?

The company is worth $1B company-- so they have money and a good track record

[walrus]

whats so special about " Kythera"? is that another five-forever years treatment?

Perhaps, but the difference is that this actually has a sound scientific background in support.

[Scientalk56]

whats so special about " Kythera"? is that another five-forever years treatment?

[HairlossAt15]

I'm sure once everything settles down they will release some more info, maybe they will give a timeline this week.

[It's2014ComeOnAlready]

I've read another article that speaks about drug repurposing. It says: The amount of time saved will depend on the amount of data publicly available on the compound, the stage of its development, and the length of trials required for the specific therapeutic target selected, as well as the amount of formulation required, particularly if this involves a change in route of administration. “At a minimum, a strong phase 2 proof-of-concept study can lead directly to phase 3 trials and commercialization in a few years, though in practice there is almost always additional information required, particularly if there is a change in the dosing and administration or if the MOA [mechanism of action] for the new indication is not well characterized,” says Flostrand.

Data publicly available: 7 studies, 8 clinical trials
Stage of Development: Has gotten through phase 3
Length of trial required for specific therapeutic target: hair cycling takes a while, but within the bounds of the length of a clinical trial
Dosing: already complete
Mechanism of action: has been established in earlier trials and studies
Administration: the only real issue. May be administered topically, but if it is successful in POC, there should be no issue.

[It's2014ComeOnAlready]

How do you not have an electronic filing system or database in this age? I hope the FDA doesnt move at turtle pace for anything having to do with this.

The red tape of bureaucracy.

[burtandernie]

I read an article recently in nature medicine that states by having an electronic filing system or database, clinical trials can be moved along a lot faster. Email, in this case would be helpful.

How do you not have an electronic filing system or database in this age? I hope the FDA doesnt move at turtle pace for anything having to do with this.

[It's2014ComeOnAlready]

I'm not sure clinical trials move any faster now than they used to. Pretty sure they don't. The science does for sure.

I read an article recently in nature medicine that states by having an electronic filing system or database, clinical trials can be moved along a lot faster. Email, in this case would be helpful.