Any news??

[It's2014ComeOnAlready]

i was losing hair 5 years ago and today i am not. maybe one day when im 45 and married ill be bald but better than being 25 and bald while single. thankful for finasteride and if there are additional things i can do to prolong hairloss on top of transplant options, then how is that dumb? i dont care if im bald when im 50.

New treatment options are coming a lot sooner than a cure. Giving a wider range of people (including women) options to deal with their hair loss is something we want as much as a pharmaceutical company wants. It would be a cash cow, because you'd have to keep buying it over and over. Thank god the patent for Propecia is up, and the medical world has realized how much of an imperfect drug it is for hair loss.

[tedwuji]

New treatment options are coming a lot sooner than a cure. Giving a wider range of people (including women) options to deal with their hair loss is something we want as much as a pharmaceutical company wants. It would be a cash cow, because you'd have to keep buying it over and over. Thank god the patent for Propecia is up, and the medical world has realized how much of an imperfect drug it is for hair loss.

i love my propecia and im eager for new options.

[Jasari]

The following study (it's not new) is why this forum is dumb, and we should all just learn to deal. After 30 months of balding, follicles become fibrotic and basically reviving them is a lost cause. Anyone who has lost hair and is expecting replicel or CB or SM or any of these things to bring their hair back is delusional. The fact that Replicel touts their product as a possible cure is ridiculous and gives false hope. there's no way DSC cells are going to be able to migrate to follicles that are fibrotic and turn things around.




Konstantinova N, Korotkii N.G, Sharova N, Barhunova E, Gaevski D. Nioxin Research Inc, AtlantaIrreversibility of hair follicle changes after 30 months of Androgenetic Alopecia.
, USA Moscow Medical University
We studied horizontal and vertical biopsy from 15 caucasian 24-41 year old males diagnosed with bitemporal recession Androgenetic Alopecia (AA) for 1.5 –18 years (average 7.4 years). All 15 biopsies were stained with H&E, Van Gieson and with other collagen specific stainings. 1. Eleven pts with AA longer than 3 years had perifollicular fibrosis - collagen fibers were compact and formed a small scar-like formation around each anagen hair follicle(HF). Two patients - 33 year old with 18 month AA and 23 year old with 20 month AA did not have these hair follicle changes. Two 26-year-old patients with 30 and 36 month AA respectively were found to have some not so severe collagen fiber changes. 2. Infundibulum of HF dilatated 124-192 mm and most of them covered with keratinazed plug lacking normal hair shaft growth. 3. Decreased number of hair follicles 1.75-2,45 per sq. mm from 3.5-5 per sq. mm in control group. 4. None of anagen HF was situated in subcutaneous fat. We showed a correlation between length of the AA and severity/ thickness of perifollicular fibrosis. The result of this study is that any treatment of AA is recommended to start earlier than 30 months from first signs of AA. This should prevent irreversible collagen changes associated with “fibrotic incapsulation” of most anagen HF in involved areas, which usually leads to loss of normal blood supply, innervation, and subsequent miniaturization and prevention of hair from normal cycling.

The only issue with current studies moving forward is that they are based on current technology. The results aren't always set in stone long term.

In any case cell based treatments appear to be the direction for the future. While estimating time schedules is virtually useless, at least the breakthrough are closer to an exponential timeline [as opposed to a linear timeline].

The other factor to keep in mind is that permanent maintenance is actually a cure [Not for us] - but for the youth moving forward. This could be here in 5 years - It could be here in 100 years. Guessing is virtually impossible.

IMO the best case scenario for norwood 4's and up moving forward is something decent for maintenance, a growth stimulant that can regain one point on the Norwood scale and a decent HT to fix the rest. [Realistically that's actually close enough to a cure for some].

[thequestion]

What is SM please? Thank you.

[burtandernie]

I think this has some potential -Setipriprant. Especially considering its based off the PGD 2 stuff.