baicalin, active ingredient against AGA
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I put powder directly in Voltaren Gel (diclofenac) some claim it can be a growth factor, I dont really believe it, but I give it a try ... I dont know if it's the best mix against AGA but it's easy to make. Gel becomes yellow/orange -
I have the same question , it looks very promising , Is there any more study and is anybody here and know what vehicle would be the best to use?Leave a comment:
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I bought some baicalin powder, but it doesn't seem to dissolve well in either ethanol or water. Can anyone advise?Leave a comment:
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Can anyone advise how to make a topical solution? Is it water or fat soluble?Leave a comment:
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I'm curious about this as well. Is anyone testing it?
What could the powder be dissolved in?Leave a comment:
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Too bad, I'm just not fond of smearing anything on my hair every day since I use fibres and I'm in constant contact with people etc...
I'll closely monitor your progress guys, I wish oral intake has an effect, dosage is really not an issue since this is cheap.Leave a comment:
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Came across this one today might be interesting for you OP.
Baicalin, a flavonoid isolated from Scutellaria baicalensis, is known to have multiple biological functions. Recent studies have demonstrated that baicalin treatment increases alkaline phosphatase activity (ALP) and osteoprotegerin secretion by osteoblasts. Furthermore, baicalin induces the differen …
Baicalin, a flavonoid, affects the activity of human dermal papilla cells and promotes anagen induction in mice
Abstract
Baicalin, a flavonoid isolated from Scutellaria baicalensis, is known to have multiple biological functions. Recent studies have demonstrated that baicalin treatment increases alkaline phosphatase activity (ALP) and osteoprotegerin secretion by osteoblasts. Furthermore, baicalin induces the differentiation of cultured osteoblasts via the activation of the Wnt/β-catenin signaling pathway. In this study, we evaluated the hair growth-promoting effects of baicalin in human follicular dermal papilla (DP) cells. A reporter assay and Western blotting were used to assess the effect of baicalin on β-catenin signaling in DP cells. ALP activity and messenger RNA (mRNA) expression were examined by ALP staining and real-time polymerase chain reaction (PCR), respectively. Growth factor expression levels were also evaluated using real-time PCR. Finally, the effect of baicalin on hair growth in vivo was examined by topical application of baicalin on the shaved dorsal skin of C57BL/6 mice. Our results indicate that baicalin activates Wnt/β-catenin signaling in a dose-dependent manner in human DP cells. ALP mRNA expression and activity were significantly induced in the presence of baicalin. In addition, treatment with baicalin induced the mRNA expression of growth factors, such as insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF). Moreover, compared to vehicle treatment, baicalin treatment induced an earlier conversion from telogen to anagen. Our results strongly suggest that baicalin promotes hair growth by regulating the activity of DP cells.Leave a comment:
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