We have a vehicle for CB-03-01: VERSAPRO

[inbrugge]

Kudu, do you have any ideas on who would be the best people to try to contact that could instruct use proper iont. use for cb, fin, etc. Spas, universities, pharmacies?

[Kudu]

Kudu, do you have any ideas on who would be the best people to try to contact that could instruct use proper iont. use for cb, fin, etc. Spas, universities, pharmacies?

There is plenty of articles, instructional videos, and forums that can help you learn how to use a device. The problem is using a device with the chems we need. No doctor or university will aid someone in using an experimental chemical with a device, and a spa wouldn't have a clue. The only way to get the proper formulas for CB would be to contact a supplier and have them create it.
If you had the cash for that then you would have to worry about stability, the proper gel, actually operating the machine correctly... It goes on and on. It would suck to invest that much money into something for it to not work. If you do have the resources for it then there would still be some trial and error before it could be done correctly to see results.

If everything went well, had the proper forms of things like bimatoprost or CB, and done right, you would probably see some serious results in a short time. Unfortunately, getting the proper form is a serious roadblock.

[Kudu]

do you think we'll be needing this device for cb when it comes out?

We shouldn't, they probably have a proper vehicle that we already know about for CB. It's just a concentration issue. I think iontophoresis is used as a sales gimmick. " Look at how phenomenal these results are with our new product! (with iontphoresis)" iontphoresis increases the efficacy of every topical. CB isn't going to be amazing other than side free, they just made it look like it with ionto.

[blondetooth]

Does anyone really think that topical CB31 is honestly more effective compared to topical .5 gel capsule Dutasteride on scalp?

[hellouser]

We shouldn't, they probably have a proper vehicle that we already know about for CB. It's just a concentration issue. I think iontophoresis is used as a sales gimmick. " Look at how phenomenal these results are with our new product! (with iontphoresis)" iontphoresis increases the efficacy of every topical. CB isn't going to be amazing other than side free, they just made it look like it with ionto.

Wouldn't they have to use topicals in trials to sell AS a topical? If they only used iontophoresis, then wouldnt that mean it'd only get approved used in the same manner?

[lilpauly]

Wouldn't they have to use topicals in trials to sell AS a topical? If they only used iontophoresis, then wouldnt that mean it'd only get approved used in the same manner?

well yes . why dont u check what they are using in the trials ! cb 5% applied 2x a day

[lilpauly]

http://clinicaltrials.gov/ct2/show/NCT02279823

[rdawg]

interesting that it's only 6 months, this trial will be done by the summer, so surely we'll know then if the solution will work!

but does this mean they will be able to go into phase III right after if they want to? or will they have to do a IIb?

[It's2014ComeOnAlready]

Hard to say, but since IIb is efficacy and safety. It seems like it might not be necessary given that they know this solution is well tolerated, and we'll know it's efficacy after the POC trial.

[It's2014ComeOnAlready]

I have a lot of hopes riding on this drug, as I'm sure many others do. I'd much rather go with something I can slap on my head than shrink my prostate.

[blondetooth]

Thats what topical fin is for... or better yet, break a DUT liquid capsule open and rub on scalp. DUT is 100x more potent than fin in some areas of science...

[blondetooth]

Also there is no suck thing as side free, sides usually occur as a law of physics. Unless the scientists get lucky.

But dont expect CB31 to be side free just because its a topical. In fact it needs to go systemic to work, just like a oral pill.

[blondetooth]

http://clinicaltrials.gov/ct2/show/NCT02279823

What a waste of time, they are using CB31..... yes...... but Minoxidil too, how stupid are they.

[hellouser]

Also there is no suck thing as side free, sides usually occur as a law of physics. Unless the scientists get lucky.

But dont expect CB31 to be side free just because its a topical. In fact it needs to go systemic to work, just like a oral pill.

FALSE.

Please respect the intelligence of the forum and don't post misinformation like that. CB-03-01 does NOT work by going system.

[joachim]

What a waste of time, they are using CB31..... yes...... but Minoxidil too, how stupid are they.

not true. minoxidil is mentioned as exclusion criteria.