Lets Get CB-03-01 DONE. We are SO close.

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  • Desmond84
    Senior Member
    • Oct 2012
    • 987

    #91
    Hey guys. I'll be posting later this weekend but thought I'll let you know now. I found the right vehicle for CB. It is super cheap (~$20/100g) and available in Australia, US and most probably Canada. I double checked it with a formulation expert and got the tick of approval

    It was all by chance. Will post details when I get back on Sunday.

    Consider this problem solved.

    Comment

    • sdsurfin
      Senior Member
      • Sep 2013
      • 702

      #92
      Originally posted by Desmond84
      Hey guys. I'll be posting later this weekend but thought I'll let you know now. I found the right vehicle for CB. It is super cheap (~$20/100g) and available in Australia, US and most probably Canada. I double checked it with a formulation expert and got the tick of approval

      It was all by chance. Will post details when I get back on Sunday.

      Consider this problem solved.
      Haha another ridiculously positive forward looking statement. Hope you're right buddy.

      Comment

      • LMS
        Senior Member
        • Dec 2012
        • 226

        #93
        Originally posted by sdsurfin
        Haha another ridiculously positive forward looking statement. Hope you're right buddy.

        Haha this, for our sake I hope you're right Desmond... I hope you're right.

        Comment

        • LMS
          Senior Member
          • Dec 2012
          • 226

          #94
          Originally posted by Desmond84
          Hey guys. I'll be posting later this weekend but thought I'll let you know now. I found the right vehicle for CB. It is super cheap (~$20/100g) and available in Australia, US and most probably Canada. I double checked it with a formulation expert and got the tick of approval

          It was all by chance. Will post details when I get back on Sunday.

          Consider this problem solved.

          triazolone based vehicle?

          Comment

          • JD59
            Junior Member
            • Aug 2014
            • 5

            #95
            Originally posted by Desmond84
            Hey guys. I'll be posting later this weekend but thought I'll let you know now. I found the right vehicle for CB. It is super cheap (~$20/100g) and available in Australia, US and most probably Canada. I double checked it with a formulation expert and got the tick of approval

            It was all by chance. Will post details when I get back on Sunday.

            Consider this problem solved.
            Are you saying that you have a vehicle and a way we could use this starting soon? Also, where would we go about even buying CB and this vehicle? Last, what evidence do you have that what you are saying will actually work? I don't doubt CB works, just curious how you know the way you are saying doing this will work.

            PS: Also, when I post this, I am not arguing against you at all. You have been an extremely helpful person on these boards. I am just curious is all.

            PPS: Would you suggest we drop the finasteride finally and start this stuff after you reveal what you have? I have never started finasteride because when I did a month ago I got side effects I think. I do minoxidil now, but am considering trying finasteride again the way you described to do it (.25mg every 3.5 days). However, if you are saying this is ready to go, I may just hold off and give this a shot instead . Or, would you just suggest someone like me just use minoxidil? I only been using it for about a month.

            Comment

            • sdsurfin
              Senior Member
              • Sep 2013
              • 702

              #96
              Originally posted by JD59
              Are you saying that you have a vehicle and a way we could use this starting soon? Also, where would we go about even buying CB and this vehicle? Last, what evidence do you have that what you are saying will actually work? I don't doubt CB works, just curious how you know the way you are saying doing this will work.

              PS: Also, when I post this, I am not arguing against you at all. You have been an extremely helpful person on these boards. I am just curious is all.

              PPS: Would you suggest we drop the finasteride finally and start this stuff after you reveal what you have? I have never started finasteride because when I did a month ago I got side effects I think. I do minoxidil now, but am considering trying finasteride again the way you described to do it (.25mg every 3.5 days). However, if you are saying this is ready to go, I may just hold off and give this a shot instead . Or, would you just suggest someone like me just use minoxidil? I only been using it for about a month.
              You can't possibly get these answers. No one knows if CB works, not even the people developing it. it's still in trials. also if desmond hasn't tried the vehicle already with success, then he can't know if it works either. he's a great forum poster with a good attitude, but CB is still going to be way too expensive to buy on the black market all the time at the concentrations you need. I talked to cosmo a while back and they said their acne version is way too dilute for use with MPB, and they are trying higher concentrations for hair loss. In order to get those amounts you'd be spending a fortune on CB, which has not yet been proven safe or effective by anybody. will still be interesting to see people guinea pig this stuff though. might give some hope for the actual product.

              Comment

              • inbrugge
                Senior Member
                • Oct 2013
                • 244

                #97
                Guys, I haven't been able to visit here recently. Desmond's update is a great one, but I believe we should still pursue iontophoresis devices. The more alternatives we have, the better. Galvanic devices still have great potential, and here we have good momentum to start something. If we get something out of here, it could lead to advancements for all existent treatments.

                Comment

                • petewete
                  Junior Member
                  • Mar 2011
                  • 19

                  #98
                  Originally posted by sdsurfin
                  You can't possibly get these answers. No one knows if CB works, not even the people developing it. it's still in trials. also if desmond hasn't tried the vehicle already with success, then he can't know if it works either. he's a great forum poster with a good attitude, but CB is still going to be way too expensive to buy on the black market all the time at the concentrations you need. I talked to cosmo a while back and they said their acne version is way too dilute for use with MPB, and they are trying higher concentrations for hair loss. In order to get those amounts you'd be spending a fortune on CB, which has not yet been proven safe or effective by anybody. will still be interesting to see people guinea pig this stuff though. might give some hope for the actual product.

                  Everybody knows about the hurdles and difficulties. Yes it may be relatively expensive but its not IMPOSSIBLE to afford. Neither is it IMPOSSIBLE to find the right dosage if all of us try together. Lets try to keep a positive attitude.

                  Comment

                  • inbrugge
                    Senior Member
                    • Oct 2013
                    • 244

                    #99
                    Kudu, Phatalis, and all others interested.

                    I think we should still continue to look into iontophoresis. Yes, Desmond's discoveries are really amazing. If people get on this and take responsibility to track their progress with photos, by new years we could tell if it provides any positive results like it did on the Cosmo trial.

                    However, the more alternatives we have the better. I still believe iontophoresis is a strong tool for enhancing all other existing treatments. Even if we solve the vehicle problem of CB through Desmond's or some other means, it doesn't mean we can't use iontophoresis to improve minoxidil/spiro/fin/etc delivery. If CB works great to halt hair loss, we still might need to deliver growth factors and ionto could be very useful for that.

                    I will post some articles that I have found here. Hopefully, we can all look through them and find some ideas.

                    Also, I believe we should focus on the more feasible devices that are around 300$. Even if we had success with the device costing 10,000's of dollars, it wouldn't make that big of a difference for the average user. Whereas with the former option, most people could afford such a machine for their homes, and its usage is not that complicated.

                    Maybe, we should continue this discussion in a separate topic "Let's get Iontophoresis done" since CB seems to be solved for now.

                    General info on Iontophoresis.


                    Iontophoresis, applying minoxidil to scalp, direct current
                    A thin layer of a drug in a liquid form in a carrier is applied to the skin. Thereafter, 15-30 milliamps of a D.C. current is applied to the skin and drug by an iontophoresis device capable of being hand held and activated by thumb contact with a positive electrode and scalp skin contact with a negative electrode. The device has a two component housing enclosing an electrical circuit connecting the two electrodes. The circuit utilizes a 9 V battery, two load regulators, two capacitors, a momentary switch and a 2V-40V output range DC/DC converter. Alternatively, negative electrodes of varying structure can be plugged into the device to provide multi-purpose application to the scalp and the positive electrode can be separately plugged to the device to free the hand of the treating technician.


                    Method for stimulating hair growth with cationic derivative of minoxidil using therapeutic iontophoresis
                    This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair growth. Each of the cationic derivatives of Minoxidil are synthesized by reacting the Minoxidil parent compound with an organic or an inorganic acid to form the cationic derivative.

                    This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair growth. Each of the cationic derivatives of Minoxidil are synthesized by reacting the Minoxidil parent compound with an organic or an inorganic acid to form the cationic derivative.


                    Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia.
                    Although minoxidil (MX) is a drug known to stimulate hair growth, the treatment of androgenic alopecia could be improved by delivery strategies that would favor drug accumulation into the hair follicles. This work investigated in vitro the potential of iontophoresis to achieve this objective using M …


                    Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers


                    Development of a portable iontophoretic drug delivery device with in-vitro experiments for androgeneticalopecia treatment


                    Topical delivery of active principles: The field of dermatological research


                    Design and Implementation of Iontophoresis Multiple Flexible Sensors for Treatment of Hair Loss

                    THE USE OF ACETIC ACID IONTOPHORESIS IN THE MANAGEMENT OF A SOFT TISSUE INJURY


                    Iontophoresis: Applications in Transdermal Medication Delivery


                    Transdermal Administration of Anti-Inflammatory Medications in Sports Injuries: Use of Iontophoresis and Phonophoresis to Enhance Delivery


                    Enhanced transfollicular delivery of adriamycin with a liposome and iontophoresis.
                    To find a better way to deliver drugs into hair follicles, we tried two approaches: single topical application using various liposomes; and iontophoresis combined with topical application of ionic liposome. After delivery of adriamycin (ADR) to wax-depilated rat skin, the transport of the drug was e …


                    Cosmo reports exciting results in P.O.C. alopecia study


                    VITAMIN C IONTOPHORESIS

                    Comment

                    • Pelopeleon
                      Junior Member
                      • May 2014
                      • 29

                      I have looked in some spanish websites, and you cand find some second hand-used machines for iontophoresis. Some of them cost between 60-200 euros (77-381 dolars, but probably cheaper). Maybe in USA, Uk, France, Germany and other countries you can get a used machine too... So, what do you need more, I mean, if you have the machine and some CB purchased on internet?

                      Comment

                      • lilpauly
                        Senior Member
                        • Feb 2012
                        • 1084

                        cosmo is using 5% appl;ied 2x a day.

                        Comment

                        • pagedo
                          Junior Member
                          • Oct 2014
                          • 21

                          Originally posted by lilpauly
                          cosmo is using 5% appl;ied 2x a day.
                          Can you source where they stated that they would be applying CB twice a day? and where they said that it was going to tested as a "gel"?

                          Thanks

                          Comment

                          • cichlidfort
                            Senior Member
                            • Jan 2013
                            • 262

                            Originally posted by Pelopeleon
                            I have looked in some spanish websites, and you cand find some second hand-used machines for iontophoresis. Some of them cost between 60-200 euros (77-381 dolars, but probably cheaper). Maybe in USA, Uk, France, Germany and other countries you can get a used machine too... So, what do you need more, I mean, if you have the machine and some CB purchased on internet?
                            Lol this sounds ridiculous and a disaster waiting to happen. 99% of the people on here won't know what the hell they are doing with this and who knows the short and long term risks.

                            Comment

                            • cichlidfort
                              Senior Member
                              • Jan 2013
                              • 262

                              Originally posted by lilpauly
                              cosmo is using 5% appl;ied 2x a day.
                              We need pictures to prove results are real. I see so much talk about CB but nothing to show for.

                              Comment

                              • lilpauly
                                Senior Member
                                • Feb 2012
                                • 1084

                                Originally posted by pagedo
                                Can you source where they stated that they would be applying CB twice a day? and where they said that it was going to tested as a "gel"?

                                Thanks
                                yes man i will have to find the post , i emailed them way back,

                                Comment

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