China: "We have maintained DP hair-inductive characteristics using eCTGF in culture"

[Arashi]

I know exactly what I'm talking about. It's you who does not know what he's talking about just like when you trumpeted to the world that hair loss was cured a few months ago.

1. The study results are not just perceived regrowth.

2. There are also impressive pictures.

3. There is also another study using micro-needling and AAPE which shows hair growth

4. Histogen's established regrowth also counts because AAPE/HARG is essentially the same thing as Histogen only better because AAPE is nature's own version of the same thing plus AAPE contains more stuff than Histogen.

5. The science behind AAPE/HARG is backed up by the discovery of a top Yale researcher who obviously knows a lot more than you do.

6. The science behind AAPE is supported by Dr. Gardner and Dr. Jahoda because both will use adipose cells in their protocols so that they can make the exact same growth factors/proteins ithat are inside of AAPE/HARG become part of their treatment mix. In other words, Gardner and Jahoda will put AAPE into their protocols by way of putting the cells into their protocols that create AAPE. Gardner and Jahoda are not putting those adipiose cells into their protocols because they believe that the cell linings will promote hair growth - they are putting adipose cells into their protocols for the exact and specific purpose of getting those cells to secrete AAPE into the follicles. Open up your eyes - in a roundabout way Jahoda and Gardner are confirming that AAPE promotes hair growth.

LOL, Ok so I got it all wrong, thanks for explaining it to me. I now understand you will become millioniare with your clinic in The Bahama's. You deserve it man. And you're right, no need to test anything, before setting up the clinic, just invest your money and go ahead. Easy as that. Good luck with your clinic ! But can you please do us all a favour and stop cluttering these forums with your AAPE posts ? Thanks JarJar.

[Arashi]

Arashi can you explain in a dumbed down way what exactly Desmond's post means? Does this mean they've foubd a way to make the hairs regenerate? What exactly needs to happen if this is the case in order for the multiplication if hairs to work? I assume they'll do trials in an area with less strict standards for testing to get it out sooner...

It sounds like they've found a new method of culturing DP cells while preserving their hair inducing ability. In the summary they didnt specify though the most important thing we would want to know: how much do the cultured cells resemble their original counter part and thus, how 'natural' do the resulting hairs look ? Either way, it's again a step in the right direction at least. Hopefully Desmond has some more info on this !

[Desmond84]

so desmond, what does it say exactly in the paper?
does it mean that DP cells can be cultured now with 100% gene expression?
does that mean that jahoda and all other teams are able to multiply the cells without any problems now when they take this finding as reference for the culturing methods?
is the puzzle finally solved or just another step towards finding the optimum?

Great question. So, I read the paper in detail last night and it is definitely not on the same level as Jahoda's or Lauster's work! They were simply testing one of Dr Lindner's ideas from back in 2011 to see if it's true. I was actually surprised to find Dr Lindner's papers and patents referenced all over this paper!

They simply tested CTGF to see if it improves hair-inductivity and it did. They never conducted Dr Jahoda's full gene-expression comparison study, which is really disappointing.

However, reading this paper made me even more confident in Lindner/Atac's work now, since they were onto this 3 years ago. As I said, these teams know way more than they let on and are keeping so much of it in high secrecy. They seemed very confident we will have this puzzle solved within the next few years if not sooner!

So to answer your question: A total gene analysis comparison was NOT conducted (only gene expression of specific markers were investigated), the DP cells cultured were NOT implanted in a foreskin or other assays to see their hair-inducing potential and they were not even cultured as well as Jahoda or Lauster's team! They simply dumped it in a well (3D) and added a whole bunch of chemicals to reduce adhesiveness. Jahoda & Lausters methods are far more delicate with DP cells.

Nevertheless, it adds more weight to Berlin-Uni's work and that's exciting

[Desmond84]

Jar jar (nameless) could you please stay on topic in each thread. If you like, make a thread about this new therapy and we'll discuss it there. It just makes it so much harder to follow specific discussions when it gets mixed up with other topics.

Thanks brother.

[Desmond84]

BTW, awesome find Desmond !! Would love to learn some more about this !

Arashi, the papers available on SAGA in the research section Enjoy the read

[joachim]

desmond, by the way, what happened to the findings you posted in that other thread, about a chinese team which claimed to have retained all the hair characteristics with their culturing method (matrigel). you said you will read the full article when you get your hands on it but never posted a final conclusion in that same thread.

i was wondering what happened to them. was it a completely different culturing method compared to jahoda and lauster?
could you find out anything about this chinese team on the hair congress? i think nobody of that team wasn't attending the congress, so what happened to them?
are they still an interesting team to follow (maybe we can even contact someone of them for some more details?) or was there any sign in the paper that the team's culturing method wasn't as good as it sounded?

and what about tsuji labs? any news there? is someone in contact with them?
currently it seems that lauster's team is our only hope for a full cure but still some years away until we see the first thick growing terminal hair, not to mention all clinical trials.

[JZA70]

and what about tsuji labs? any news there? is someone in contact with them?

Jesus. What's with you impatient annoying people always wanting to email someone every 5 minutes. The timeline for ALL runner ups ( Tsuji, Jahoda, Lauster) is AT LEAST 10 years. It's just getting annoying hearing the same crap over and over.

Who cares if anyone has been in contact with Tsuji labs. In his video, Takashi Tsuji clearly said TEN YEARS. Until ten years has passed, don't bother emailing him. Let them do their job FFS.

[hellouser]

Jesus. What's with you impatient annoying people always wanting to email someone every 5 minutes. The timeline for ALL runner ups ( Tsuji, Jahoda, Lauster) is AT LEAST 10 years. It's just getting annoying hearing the same crap over and over.

Who cares if anyone has been in contact with Tsuji labs. In his video, Takashi Tsuji clearly said TEN YEARS. Until ten years has passed, don't bother emailing him. Let them do their job FFS.

Because that '10 years' mark was pulled out of his ass. More so the fact that if they REALLY wanted to, they could get it done in months. And considering Japan's de-regulation of stem cell therapy, its totally possible for a treatment to make it to market within 3 years.

10 years? Who's got time for that?

[joachim]

Jesus. What's with you impatient annoying people always wanting to email someone every 5 minutes. The timeline for ALL runner ups ( Tsuji, Jahoda, Lauster) is AT LEAST 10 years. It's just getting annoying hearing the same crap over and over.

Who cares if anyone has been in contact with Tsuji labs. In his video, Takashi Tsuji clearly said TEN YEARS. Until ten years has passed, don't bother emailing him. Let them do their job FFS.

the 10 years is a general timeframe used if outcomes are unknown at all. it highly depends on what findings and breakthroughs they can achieve in the next months/years. (e.g. DP culturing problems).

if, let's say, TU Berlin would present a fully grown terminal hair TODAY which means proof of concept is done and can be reproduced any time with consistent results, then no way that this hair cloning technology will be 10 years way. there will be a way to get it earlier, like hellouser said it with japan.
thus, it's always interesting to get the current status of the researchers every few months.
tsuji labs has been quiet for a long time now. would be nice to see where they are today.

[Swooping]

Because that '10 years' mark was pulled out of his ass. More so the fact that if they REALLY wanted to, they could get it done in months. And considering Japan's de-regulation of stem cell therapy, its totally possible for a treatment to make it to market within 3 years.

10 years? Who's got time for that?

Let me give you a tip. Hover down from the clouds already right into your shoes. Cause 10 years minimum is a reality. They started culturing DP already in the 80's. 30+ years later, they still are still pretty far from cracking it.That is a reality. To even think of a COMMERCIAL treatment within 10 years is hilarious really. But hey miracles do happen right ? Lets hope so!

[ShookOnes]

Let me give you a tip. Hover down from the clouds already right into your shoes. Cause 10 years minimum is a reality. They started culturing DP already in the 80's. 30+ years later, they still are still pretty far from cracking it.That is a reality. To even think of a COMMERCIAL treatment within 10 years is hilarious really. But hey miracles do happen right ? Lets hope so!

hellrouser believes in illuminati and that researchers all over the world would prefer to get famous in 10 years rather than 3, and that brilliant teams with PhD's are dumb and take too long and....etc.

[hellouser]

hellrouser believes in illuminati and that researchers all over the world would prefer to get famous in 10 years rather than 3, and that brilliant teams with PhD's are dumb and take too long and....etc.

None of that makes sense.

[USMC]

I saw the word China and stopped there. They'd counterfeit a watermelon.

[ShookOnes]

None of that makes sense.

^ this kid believes the cure is potentially months ahead

[hellouser]

^ this kid believes the cure is potentially months ahead

Strange rebuttal coming from a guy who's gullible enough to believe 'researchers all over the world would prefer to get famous in 10 years rather than 3'

Oh well.