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  • ghostrider
    Member
    • Mar 2015
    • 49

    Hi mates

    What's so special about this? It works with wnt?

    Valproic acid (VPA), a widely used anticonvulsant, inhibits glycogen synthase kinase 3β and activates the Wnt/β-catenin pathway, which is associated with hair growth cycle and anagen induction. To assess the efficacy of topical VPA for treating androgenetic alopecia (AGA), we performed a randomized, …


    I read valproic acid has been around for years & its very cheap.

    Can anyone comment on this ?

    Comment

    • JayM
      Senior Member
      • Apr 2015
      • 411

      Originally posted by ghostrider
      Hi mates

      What's so special about this? It works with wnt?

      Valproic acid (VPA), a widely used anticonvulsant, inhibits glycogen synthase kinase 3β and activates the Wnt/β-catenin pathway, which is associated with hair growth cycle and anagen induction. To assess the efficacy of topical VPA for treating androgenetic alopecia (AGA), we performed a randomized, …


      I read valproic acid has been around for years & its very cheap.

      Can anyone comment on this ?
      Swiss uses VPA for WNT activation.

      Comment

      • ghostrider
        Member
        • Mar 2015
        • 49

        Hi mate
        Look at this


        6-bio is mentioned on thr wkiki site. I read elsewhere its 40.000 stronger than vpa.

        Why not use Lithium en zinc Dr cots approach.

        Comment

        • JayM
          Senior Member
          • Apr 2015
          • 411

          He also uses licl but only after wounding.

          Comment

          • ShookOnes
            Senior Member
            • Jun 2014
            • 209

            anyone know if this would be 100% effective depending on the mechanisms of this product? I'm a diffuser and if I could do another steroid cycle without losing hair I'd be so happy :P

            Comment

            • champpy
              Senior Member
              • Apr 2015
              • 336

              Anyone on here have any idea where to get this VPA?

              Comment

              • cratusg
                Member
                • Aug 2015
                • 31

                When will we get to know the phase 2 results? Anyone know the predicted time?

                Comment

                • champpy
                  Senior Member
                  • Apr 2015
                  • 336

                  Originally posted by cratusg
                  When will we get to know the phase 2 results? Anyone know the predicted time?
                  Not for sure, but I think they are doing another supplemental phase 2 that will last until FEB, so maybe after then will we hear about the results. Just guessing though

                  Comment

                  • MasterRay
                    Junior Member
                    • Nov 2015
                    • 4

                    The samumed presentation at the congress should be great!

                    Comment

                    • MasterRay
                      Junior Member
                      • Nov 2015
                      • 4

                      Phase 1 results

                      The samumed presentation at the congress should be great!

                      Comment

                      • rdawg
                        Senior Member
                        • Jun 2012
                        • 996

                        At the very least it shows a solid amount of effectiveness here.

                        Far more interested in the Phase II results which should come early next year, 29 respondents is tiny and at an average age of 44 that doesnt tell you much(as hairloss at that age is most likely finished or going at an incredibly slow rate).

                        Show me results on a 25 year old balding person, then you have a bit more of my attention.

                        Either way there is nothing but positive to take from this, hopefully they are testing at the maximum safe dose and at the very least provide us with an alternative to minox within the next 2-3 years!

                        Comment

                        • nameless
                          Senior Member
                          • Feb 2013
                          • 965

                          One thing that I did NOT like is that it said there is systemic absorption so that means it might lead to sexual side effects like gynecomastia and impotence just like these other drugs that get into the body.

                          Comment

                          • unbalding
                            Senior Member
                            • Sep 2014
                            • 140

                            Hmm.. Are they trying to steal thunder from Allegan. I hope they provide phase 2 results at the congress. This trial was only 14 days, so it seems to work fast. If this wasn't an aberration this could be huge.

                            MasterRay, do you work for Samumed?

                            Comment

                            • rdawg
                              Senior Member
                              • Jun 2012
                              • 996

                              Originally posted by unbalding
                              Hmm.. Are they trying to steal thunder from Allegan. I hope they provide phase 2 results at the congress. This trial was only 14 days, so it seems to work fast. I hope this want just an aberration.

                              MasterRay, do you work for Samumed?
                              Phase II is not complete until February 2016, however they may show early phase II results as it has been about a year, I'm hopeful they do that!

                              Comment

                              • MasterRay
                                Junior Member
                                • Nov 2015
                                • 4

                                No Rdawg, i just saw that on their website.

                                Comment

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