New Article: Lin28a.

[TheSwingingGate]

http://www.sciencedaily.com/releases/2013/11/131107123144.htm

Thought Desmond would like this.

[NeedHairASAP]

This is all over the news, even being toutued as a baldness cure.

Is it the real deal breakthrough or media hype?

Desmond?

[Ted]

Exciting!

http://www.dailytech.com/Mice+Regrow+Fingertips+Hair+With+Help+of+MitochondriaBoosting+Protein/article33725c.htm

[rdawg]

So many damn mice cures.

But the positive is we have another idea/product/potential cure!

Ive been on this forum for maybe 3 years on and off, end- of 2012-2013 has been filled with discoveries and companies moving forward(albeit slowly). I find there's a new announcement almost every month now.

I dont recall there being nearly this much news prior to 2012.

[burtandernie]

It should be illegal to report medical research on mice to the media. Who cares about mice how is it even news worthy? When its done and in people start reporting it as news. This stuff has a history of 100 articles and we still have nothing in humans which is all that actually counts. This belongs in a lab for more research not in the news

[walrus]

It should be illegal to report medical research on mice to the media. Who cares about mice how is it even news worthy? When its done and in people start reporting it as news. This stuff has a history of 100 articles and we still have nothing in humans which is all that actually counts. This belongs in a lab for more research not in the news

You have extremely unrealistic views of how science works.

[NeedHairASAP]

Wish an informed poster would vlarify what this means for bald bros

[crafter]

it's interesting but any treatment coming from this is a generation away.

[DepressedByHairLoss]

What pisses me off (and has pissed me off ever since I've been posting on this forum) is that these scientists will spend their entire careers tinkering around with these mouse discoveries, and not do a damn thing to benefit humans.

[hellouser]

What pisses me off (and has pissed me off ever since I've been posting on this forum) is that these scientists will spend their entire careers tinkering around with these mouse discoveries, and not do a damn thing to benefit humans.

Just like cancer research doctors... they've been gifted billions of dollars from donations without a damn thing to show for it. Its almost like theyre just bullshitting around and keeping themselves employed. All talk, ZERO results.

[TheSwingingGate]

^This.

While I don't doubt the cures for MPB and many diseases are complex, I do feel there is an element of 'politicians staying in power' when it comes to some of these researchers and their funding to keep a job.

[greatjob!]

What pisses me off (and has pissed me off ever since I've been posting on this forum) is that these scientists will spend their entire careers tinkering around with these mouse discoveries, and not do a damn thing to benefit humans.

Do you not understand the ethical, regulatory, and cost associated with human trials? There's a reason most things are tested on lower vertebrates.

[hellouser]

Do you not understand the ethical, regulatory, and cost associated with human trials? There's a reason most things are tested on lower vertebrates.

Sure... but... with all the findings theyve been able to make on mice, theyve done jack shit on humans.

[PaddyBateman]

Sure... but... with all the findings theyve been able to make on mice, theyve done jack shit on humans.

....for hairloss.

Which , to be fair, wasn't at the top of humanity's concerns for some time. Even if we wish it were.

You don't need to have had cancer, or AIDs, or heart disease to know how important it is for scientists to concentrate on them.

But..you do need to have had hairloss to understand how destructive it can be to someone's life, male or female.

[greatjob!]

Sure... but... with all the findings theyve been able to make on mice, theyve done jack shit on humans.

I understand the frustration, but it is extremely hard to get approval to trial things on humans and for good reason. For example gene therapy trials were underway in the U.S. for about a decade until in 1999 an 18 year old named Jesse Gelsinger who suffered from ornithine transcarbamylase, but was otherwise healthy was treated using an experimental gene therapy method and died four days later from massive organ failure. Another person died in Europe around the same time and since then nearly all gene therapy trials have stopped until recently.

So it's real easy to blame regulations for no treatments, which is fair to a degree since the process is pretty ridiculous, but there are reasons human trials are difficult to perform. I mean everyone who complains about regulations and the FDA, are also the people who scream the loudest about fin being poison and fin only messes with your junk. What do you think people would do if the FDA fast tracked a treatment for hairloss and it started causing cancer? Do you think all the people begging for fast track wouldn't then blame the FDA for fast tracking it?

Also in almost every mice study the end point is to kill the mice and dissect them to observe toxicity and effects on organs, that would be kind of difficult to do with humans.