Reason why there is still no cure in 2013 and the solution

[youngin]

https://www.youtube.com/watch?v=mfLLkmY_t9k So you're saying they lied in this video? Cause that's exactly what she said. They expanded dp cells in a 3d spheroid culture and they were inductive. Did you read Jahodas study? This is what NIGAM is doing right now.

[garethbale]

Hey Desmond

Thanks for the info.

Have you communicated your thoughts to any of the people looking in to cellular treatments for hair loss (Replicel, Tsuji etc)? I would have thought all thier scientists and researchers are aware of what you had suggested but I was just wondering if you's queried this with them and what their response to you was, if any.

I like your optimism about crowdfunding a project and would definitely get involved if it happened. I know Aderans parent company invested $100 million or so in, but I don't think this specifically went into Aderans Research and consequentially to Ji Gami funding. Companies such as Replicel, Histogen etc really don't have that much available cash.

[Desmond84]

This involves more of us (specially those in their early 20's) taking up degrees in Bachelor of Biotechnology, Developmental studies, and Biomedical Sciences.

We need to experiment with state of the art 3D scaffolds, growth factors, etc!

The "first dermal signal" believed to be responsible for development of DP cells in the embryo is still unknown! Finding out what molecules make up this signal may hold the key to expansion of DP cells in culture! There are some indications that Beta-catenin may be one of these first signals! Maybe we should incorporate this signal when we culture DP cells.

We need crowdfunding ideas to support Jahoda, Christiano and Cotsarelis.

If we want to see a cure in our lifetime, we need to work for it...period.

We should think of it as an investment for our future.

We need to make this thread sticky! Everyday we have more ppl realising they suffer from MPB and join this community. We need everyone to understand why there is still no cure and how can we solve it with one simple breakthrough.

[Desmond84]

OK guys, so after reading over 300 research papers on hair follicle and embryo development for 12 months, I've come to realise the only reason why we are still in this mess is only for one reason and that is:

"WE CAN NOT EXPAND DP CELLS IN CULTURE"

That is what's holding Tsuji team back, making Lauster lose interest, forcing Aderans & Intercytex to call it quits and keeping us bald!

We need the entire community and the research field to put all their focus on this problem!

In the Tsuji study for example, they had fully functional DP cells and epithelial stem cell. They simply placed them on top of each other and voila, hairs started forming immediately. We can expand epithelial stem cells in culture, but NOT DP cells...

We hear time and time again, conspiracy theories about Big Pharma holding out on the cure or the society wanting us to stay bald...BUT that is not true. The fact of the matter is, we are stuck on one final step (a crucial step)...Once we figure it out, the rest of the way has been paved for us by groups like Tsuji team and Lauster!

So, here's a small request to our great community. Read research papers. Discuss ideas of how we can go about this problem. Brain storm. And one day, either us or the scientists will figure it out.

You guys might not believe it...but the cure is that simple. Multiply fully functional DP cells and MPB will be a fashion statement.