ishrs-2013: Dr Wesley and ... Jahoda !!

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  • hellouser
    Senior Member
    • May 2012
    • 4419

    #46
    Originally posted by Arashi
    Just saw the website is up, maybe it's been up for a long time but it's the first time I saw it. Not a lot info there though. http://www.pilofocus.com/
    Looks the same as it did before.

    Any more info/evidence on donor regeneration??

    Comment

    • Arashi
      Senior Member
      • Aug 2012
      • 3888

      #47
      Originally posted by hellouser
      Looks the same as it did before.

      Any more info/evidence on donor regeneration??
      Ok, I never saw the site before.

      The meeting is supposed to start in 3.5 hours, so hopefully we'll know something later today. That is, if someone who's there reports ...

      Comment

      • hellouser
        Senior Member
        • May 2012
        • 4419

        #48
        Originally posted by Arashi
        Ok, I never saw the site before.

        The meeting is supposed to start in 3.5 hours, so hopefully we'll know something later today. That is, if someone who's there reports ...
        Apparently Dr. Nigam is there.... I just want to know about donor regen! I need to fill in my damn temples and know that future thinning can be remedied... damn it, damn it, DAMN IT!

        Comment

        • Arashi
          Senior Member
          • Aug 2012
          • 3888

          #49
          Originally posted by hellouser
          Apparently Dr. Nigam is there.... I just want to know about donor regen! I need to fill in my damn temples and know that future thinning can be remedied... damn it, damn it, DAMN IT!
          Well, what I never understood regarding pilofocus: supposedly it's a techqniue aimed at minimizing graft damage. But without graft damage, how are you going to have regrowth !?!

          Comment

          • hellouser
            Senior Member
            • May 2012
            • 4419

            #50
            Originally posted by Arashi
            Well, what I never understood regarding pilofocus: supposedly it's a techqniue aimed at minimizing graft damage. But without graft damage, how are you going to have regrowth !?!
            Why would you need graft damage for regrowth though? Are you saying disrupting grafts like through dermarolling induces regrowth?

            Comment

            • Arashi
              Senior Member
              • Aug 2012
              • 3888

              #51
              Originally posted by hellouser
              Why would you need graft damage for regrowth though? Are you saying disrupting grafts like through dermarolling induces regrowth?
              Well the whole idea is that you split a graft and both pieces repair themselves into becoming 2 grafts. http://www.ncbi.nlm.nih.gov/pubmed/23289545
              I'm not sure how you could attain regrowth if you just move the whole graft.

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                #52
                Originally posted by Arashi
                Well the whole idea is that you split a graft and both pieces repair themselves into becoming 2 grafts. http://www.ncbi.nlm.nih.gov/pubmed/23289545
                I'm not sure how you could attain regrowth if you just move the whole graft.
                Well the pilofocus procedure is supposed to suck the graft from underneath.. perhaps, if there is donor regen, there are remnants of the graft leftover or the surrounding area... or cells that turn into follicles?

                Comment

                • Arashi
                  Senior Member
                  • Aug 2012
                  • 3888

                  #53
                  Originally posted by hellouser
                  Well the pilofocus procedure is supposed to suck the graft from underneath.. perhaps, if there is donor regen, there are remnants of the graft leftover or the surrounding area... or cells that turn into follicles?
                  But the Pilofocus main goal is to not damage the graft at all. So there won't be any 'graft leftover'. Anyway this is why I'm not expecting to see regrowth, but we'll soon know more.

                  Comment

                  • brunobald
                    Senior Member
                    • Jul 2013
                    • 169

                    #54
                    But the Pilofocus main goal is to not damage the graft at all. So there won't be any 'graft leftover'. Anyway this is why I'm not expecting to see regrowth, but we'll soon know more.
                    Exactly, donor regen only works when you leave part of the graft in place, a 50/50 split in theory would be the best possible outcome. Nigam has success with transecting the follicle, if pillofocus is as accurate as we think then there is no reason why the graft cannot be transected under the scalp and then implated into the recipient.

                    Anyway lets just hear what the man has to say first, everything else is just pure speculation. My gut feeling is Nigams method may render pilofocus useless as his stem cell ****tail appears to reduce scaring to nothing, plus you have regen and a clear path to administer the stem cell ****tail. Im not sure how you would and "stem cells" or whatever the hell they are with pilofocus

                    Comment

                    • Arashi
                      Senior Member
                      • Aug 2012
                      • 3888

                      #55
                      Originally posted by brunobald
                      Exactly, donor regen only works when you leave part of the graft in place, a 50/50 split in theory would be the best possible outcome. Nigam has success with transecting the follicle, if pillofocus is as accurate as we think then there is no reason why the graft cannot be transected under the scalp and then implated into the recipient.

                      Anyway lets just hear what the man has to say first, everything else is just pure speculation. My gut feeling is Nigams method may render pilofocus useless as his stem cell ****tail appears to reduce scaring to nothing, plus you have regen and a clear path to administer the stem cell ****tail. Im not sure how you would and "stem cells" or whatever the hell they are with pilofocus
                      Nigam still hasn't proved anything at all. It turned out HASCI splitting theory might not work. So who knows ...

                      Comment

                      • hellouser
                        Senior Member
                        • May 2012
                        • 4419

                        #56
                        Originally posted by Arashi
                        Nigam still hasn't proved anything at all. It turned out HASCI splitting theory might not work. So who knows ...
                        Yeah, but HASCI and Nigams are two very different methods. HASCI might not even have any regeneration at all..

                        Comment

                        • Arashi
                          Senior Member
                          • Aug 2012
                          • 3888

                          #57
                          Originally posted by hellouser
                          Yeah, but HASCI and Nigams are two very different methods. HASCI might not even have any regeneration at all..
                          Well they're both based on wound induced neogenesis (though Nigams of course added growthfactors + his denovo technique). We'll see. I'm not too optimistic ...

                          Comment

                          • hellouser
                            Senior Member
                            • May 2012
                            • 4419

                            #58
                            Originally posted by Arashi
                            Well they're both based on wound induced neogenesis (though Nigams of course added growthfactors + his denovo technique). We'll see. I'm not too optimistic ...
                            We'll know when Mwamba confirms.

                            Comment

                            • Arashi
                              Senior Member
                              • Aug 2012
                              • 3888

                              #59
                              Originally posted by hellouser
                              We'll know when Mwamba confirms.
                              Yup.

                              Comment

                              • brunobald
                                Senior Member
                                • Jul 2013
                                • 169

                                #60
                                I know man its still up in the air, its a big if as to wether it works or not. HASCI does work, just not well enough to really get excited about it. Nigams past project are enough to make anyone dubious about anything he does. Give it a few months and Mwamba will be the judge.

                                Is today the first ISHRS talk. Can't believe they dont at least have a live audio feed broadcast on the website.

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